The Healthy Worm Database

 

This site displays the results of a literature search for compounds tested for their effects on aging related phenotypes in the nematode Caenorhabditis elegans (C. elegans). It extends the work on the terminology of aging (Fuellen et al., 2019) and on the search for aging pathways (Möller et al., 2018). For abbreviations see abbreviations.html

The collected data is expected to cover all compounds with reports on effects on healthspan that surfaced in the Pubmed search for:

(healthspan OR "healthy aging" OR fitness OR "stress resistance" OR homeostasis OR locomotion OR pumping OR "sensory perception" OR memory)
AND
(natural OR compound OR "small molecule" OR pharmaceutical OR substance OR extract OR fraction OR fruit OR vegetable OR herb OR chemical OR plant OR "secondary metabolite")
AND
("C. elegans" OR "Caenorhabditis elegans") AND (aging OR ageing) NOT (Review[ptyp])

We cordially invite you all to inform us about further compounds that should be included and other missing or incorrect details (contact: Nadine.Saul@HU-Berlin.de or Nadine.Saul@gmx.de). All data and source code is available at https://bitbucket.org/ibima/healthspancompoundswebsite.

This work was performed for the EU Horizon 2020 project 'Aging with elegans' (633589), by Nadine Saul <Nadine.Saul@HU-Berlin.de> at the Humboldt University of Berlin, Germany, and Steffen Möller <steffen.moeller@uni-rostock.de> with Georg Fuellen, IBIMA, Rostock University Medical Center, Rostock, Germany.

To cite this work, please consider our recent publication: Saul N, Möller S, Cirulli F, Berry A, Luyten W, Fuellen G. (2021) Health and longevity studies in C. elegans: the 'healthy worm database' reveals strengths, weaknesses and gaps of test compound-based studies. Biogerontology. 22(2):215-236. doi: 10.1007/s10522-021-09913-2.

References:
Fuellen G., Jansen L., Cohen A.A., Luyten W., Gogol M., Simm A., Saul N., Cirulli F., Berry A., Antal P., Köhling R., Wouters B., Möller S. (2019) Health and Aging: Unifying Concepts, Scores, Biomarkers and Pathways. Aging and Disease, 10(4), 2. doi: 10.14336/AD.2018.1030.
Möller S., Saul N., Cohen A., Köhling R., Sender S., Murua Escobar H., Junghanß C., Cirulli F., Berry A., Antal P., Adler P., Vilo J., Boiani M., Jansen L., Struckmann S., Barrantes I., Hamed M., Luyten W., Fuellen G. (2020) Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids Aging, 12(13):12534-12581. doi: 10.18632/aging.103514.

The web interface at the bottom of this page supports an interacive browsing of the data. To download all entries in a flat file that can be imported into R or Excel, also try:

Search for compounds in the input field: (Please click on compounds listed below or select checkboxes before pressing enter)

- takes some 30 seconds.

IDName (PubChem)#Cond / #PhenStrains

(hide)
oxidative stress resistance
heat stress resistance
pathogen stress resistance
UV stress resistance
osmotic stress resistance
arsenite stress resistance
metal stress resistance
salt stress resistance
mean lifespan
maximum lifespan
minimum lifespan
median lifespan
survival at a given time point
ROS level
HSPs
DAF-16 to nucleus
SODs
N(6)-Carboxymethyllysine (CML)
α-synuclein
carbonylated proteins
β-Amyloid
CTLs
proteasomal activity
SKN-1 to nucleus
triglyceride / fat / lipid content
autofluorescence
GSTs
UGTs
oxygen consumption rate (OCR)
GSH level
ATP level
germline stem cells
polyQ aggregates
thiol level
GCS-1
GPDHs
GSH-PX
level of 4-HNE
AMP:ATP ratio
phosphofructokinase activity
lipase activity
hexokinase activity
pyruvate kinase activity
level of autophagy
antioxidative capacity
mitochondrial content/quality
intestinal bacteria colonization
phosphorylation level of PMK-1
MDA level
muscle integrity
activity of acetylcholinesterase
mitochondrial DNA copy number
mitochondrial ROS production
axonal HTT aggregates
axonal dystrophy
apoptotic cells
lactate level
pyruvate level
mitochondrial membrane potential
F3-isoprostane level
mitochondrial DNA (mtDNA) integrity
CYPs
acetylcholine level
SKN-1
chemotaxis
mechanical sensory / touch response
neuronal survival / integrity
aldicarb resistance
memory
D-type GABAergic motorneurons
pharyngeal pumping
locomotion in liquid media
locomotion on solid media
duration of defecation cycles
body length / growth rate
fast body movement span
fast pharyngeal pumping span
pharyngeal total span
body wave number
food consumption
number of offspring
speed of larval development
dauer formation
embryonic lethality
vertex (progeny per day)
early reproduction
onset of egg laying
late reproduction
reproductive total span
reproductive growth span
internal hatch
0 (±)-Octoclothepin maleate (11957654) 1 / 2 N2 (wild type)
1 (Iso)lappaol A (323894) 12 / 5 N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, GR1307 [daf-16(mgDf50)], TK22 [mev-1(kn1)]
2 (R,R)-cis-Diethyl tetrahydro-2,8-chrysenediol (446849) 1 / 2 N2 (wild type)
3 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG) from Curcuma longa L (65238) 2 / 5 N2 (wild type)
4 2-Ethylthio-8-methoxy-5-oxo-1-phenyl-1,5-dihydrobenzo[b][1,2,4]triazolo[1,5-g][1,6]naphthyridine-12-carbonitrile (compound 12a) 3 / 5 N2 (wild type)
5 7-Isobutylamino-2-ethylthio-6-formyl-5-oxo-1-phenyl-1,5-dihydro-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile (compound 4c) 3 / 2 N2 (wild type)
6 7-Benzylamino-2-ethylthio-6-formyl-5-oxo-1-phenyl-1,5-dihydro-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile (compound 4f) 4 / 5 N2 (wild type)
7 Xyloketal B (10980896) 2 / 1 N2 (wild type)
8 10-O-trans-p-Coumaroylcatalpol 9 / 9 N2 (wild type), TK22 [mev-1(kn1)], GR1307 [daf-16(mgDf50)], VC199 [sir-2.1(ok434)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, NL5901 {pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]}
9 Xyloketal, derivate 10 1 / 1 N2 (wild type)
10 Xyloketal, derivate 11 1 / 1 N2 (wild type)
11 Xyloketal, derivate 12 1 / 1 N2 (wild type)
12 Xyloketal, derivate 13 1 / 1 N2 (wild type)
13 Xyloketal, derivate 14 1 / 1 N2 (wild type)
14 Xyloketal, derivate 15 4 / 6 N2 (wild type), PS3551 [hsf-1(sy441)], CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}
15 Xyloketal, derivate 16 1 / 1 N2 (wild type)
16 Xyloketal, derivate 17 1 / 1 N2 (wild type)
17 Xyloketal, derivate 18 2 / 1 N2 (wild type)
18 18α-Glycyrrhetinic acid (73398) 23 / 14 N2 (wild type), EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], heterozygous, EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], heterozygous, EU40 [skn-1(zu129)/nT1[unc-?(n754) let-?]], EU40 [skn-1(zu129)/nT1[unc-?(n754) let-?]], heterozygous, CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}, LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}, unknown strain; genotype: [{[Pvha-6::UIM2-ZsProSensor]}, DR26 [daf-16(m26)], CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CL2331 {dvIs37 [myo-3p::GFP::A-Beta (3-42) + rol-6(su1006)]}
19 Xyloketal, derivate 19 1 / 1 N2 (wild type)
20 2,3-Dehydrosilybin A 1 / 1 N2 (wild type)
21 2,3-Dehydrosilybin A/B 9 / 14 N2 (wild type), DR26 [daf-16(m26)], CL2331 {dvIs37 [myo-3p::GFP::A-Beta (3-42) + rol-6(su1006)]}, GMC101 {dvIs100 [unc-54p::A-beta-1-42::unc-54 3'-UTR + mtl-2p::GFP]}
22 2,3-Dehydrosilybin B 1 / 1 N2 (wild type)
23 Xyloketal, derivate 2 2 / 1 N2 (wild type)
24 20-Galloyl-2,3-dehydrosilybin A/B 1 / 1 N2 (wild type)
25 Xyloketal, derivate 20 (102203087) 1 / 1 N2 (wild type)
26 Xyloketal, derivate 21 1 / 1 N2 (wild type)
27 Xyloketal, derivate 22 1 / 1 N2 (wild type)
28 Xyloketal, derivate 23 1 / 1 N2 (wild type)
29 Xyloketal, derivate 24 1 / 1 N2 (wild type)
30 Xyloketal, derivate 25 1 / 1 N2 (wild type)
31 Xyloketal, derivate 26 1 / 1 N2 (wild type)
32 Xyloketal, derivate 27 1 / 1 N2 (wild type)
33 Xyloketal, derivate 28 1 / 1 N2 (wild type)
34 Xyloketal, derivate 29 1 / 1 N2 (wild type)
35 3,4-Dichloroisocoumarin (1609) 1 / 2 N2 (wild type)
36 3,7-Dimethyl-2,3-dehydrosilybin A/B 1 / 1 N2 (wild type)
37 Xyloketal, derivate 3 1 / 1 N2 (wild type)
38 Xyloketal, derivate 30 1 / 1 N2 (wild type)
39 Xyloketal, derivate 31 1 / 1 N2 (wild type)
40 Xyloketal, derivate 32 1 / 1 N2 (wild type)
41 Xyloketal, derivate 33 1 / 1 N2 (wild type)
42 Xyloketal, derivate 34 1 / 1 N2 (wild type)
43 Xyloketal, derivate 35 1 / 1 N2 (wild type)
44 Xyloketal, derivate 36 1 / 1 N2 (wild type)
45 Xyloketal, derivate 37 1 / 1 N2 (wild type)
46 4-Caffeoylquinic acid (9798666) 1 / 1 N2 (wild type)
47 4-Phenyl-3-furoxancarbonitrile (1756) 1 / 2 N2 (wild type)
48 4-Hydroxy-E-globularinin 12 / 11 N2 (wild type), TK22 [mev-1(kn1)], GR1307 [daf-16(mgDf50)], VC199 [sir-2.1(ok434)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}
49 Xyloketal, derivate 4 1 / 1 N2 (wild type)
50 5-Caffeoylquinic acid (1794427) 1 / 1 N2 (wild type)
51 Xyloketal, derivate 5 2 / 1 N2 (wild type)
52 Xyloketal, derivate 6 2 / 1 N2 (wild type)
53 7-Cyclopentyl-5-(4-phenoxy)phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine (6603792) 1 / 2 N2 (wild type)
54 7-Methyl-2,3-dehydrosilybin A/B 1 / 1 N2 (wild type)
55 Xyloketal, derivate 7 2 / 1 N2 (wild type)
56 Xyloketal, derivate 8 1 / 1 N2 (wild type)
57 Xyloketal, derivate 9 1 / 1 N2 (wild type)
58 AMN082 (11698390) 1 / 2 N2 (wild type)
59 Acacetin 7-O-α-l-rhamnopyranosyl (1–2) β-D-xylopyranoside (ARX) from Premna integrifolia 16 / 13 N2 (wild type), TK22 [mev-1(kn1)], DA1116 [eat-2(ad1116)], GR1307 [daf-16(mgDf50)], VC199 [sir-2.1(ok434)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], PS3551 [hsf-1(sy441)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
60 Acacetin (5280442) 10 / 13 N2 (wild type), TK22 [mev-1(kn1)], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, NL5901 {pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]}
61 Ag nanoparticles (particle size of 8 nm) 11 / 3 N2 (wild type)
62 Agrimonia procera, ethanol extract 30 / 6 N2 (wild type), CF1038 [daf-16(mu86)], CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
63 Alanine (5950) 1 / 2 N2 (wild type)
64 Alanine/tyrosine mixture 1 / 2 N2 (wild type)
65 Alaskan blueberry extract 7 / 6 N2 (wild type)
66 Alaskan chaga extract 6 / 6 N2 (wild type)
67 Alaskan cranberry extract 7 / 6 N2 (wild type)
68 Alaskan crowberry extract 3 / 1 N2 (wild type)
69 Allantoin (204) 5 / 3 N2 (wild type), DA465[eat-2(ad465)], GR1307 [daf-16(mgDf50)]
70 Alloaromadendrene (Essential oil from Cinnamomum osmophloeum Leaves) (91354) 8 / 4 N2 (wild type), GR1307 [daf-16(mgDf50)]
71 Allyl isothiocyanate (5971) 33 / 7 N2 (wild type), MJCU049 {kIs48 [gst-4p::gfp]}, MJCU050 {kIs22 [ugt-13p::gfp]}
72 Alpinia zerumbet Leaf (Hot water extract) 3 / 2 N2 (wild type)
73 Alpinia zerumbet Leaf (Phenol-rich fraction) 8 / 5 N2 (wild type), CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
74 Amoxapine (2170) 1 / 2 N2 (wild type)
75 Amperozide hydrochloride (73334) 1 / 2 N2 (wild type)
76 Anacardium occidentale, hexane extract 30 / 12 N2 (wild type), CF1038 [daf-16(mu86)], TJ375 {gpIs1 [hsp-16.2p::GFP]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}, BA17 [fem-1(hc17)], TK22 [mev-1(kn1)]
77 Anacardium occidentale, methanol extract 33 / 12 N2 (wild type), CF1038 [daf-16(mu86)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], TJ375 {gpIs1 [hsp-16.2p::GFP]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}, BA17 [fem-1(hc17)], TK22 [mev-1(kn1)]
78 Whole apple extract (135316389) 3 / 9 N2 (wild type)
79 Green tea (Camellia sinensis), aqueous extract 7 / 5 N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}
80 Arctigenin (64981) 12 / 5 N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, GR1307 [daf-16(mgDf50)], TK22 [mev-1(kn1)]
81 Arctiin (100528) 12 / 5 N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, GR1307 [daf-16(mgDf50)], TK22 [mev-1(kn1)]
82 Arsenite (443495) 12 / 10 N2 (wild type), EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], unknown strain [daf-16(mgDf47)], VC2268 [tin-9.1(ok2194)], VC128 [mtl-2(gk125)]
83 Ascarosides ascr#2 51 / 3 N2 (wild type), VC199 [sir-2.1(ok434)], NL3909 {unc-119(ed3); pkIs1642[unc-119(+) + R11A8.5(+) + sir-2.1(+)]}, NL3908 {unc-119(ed3); pkIs1641[unc-119(+)]}, unknown strain {daf-16(mgDf50); unc-119(ed3); pkIs1642[unc-119(+) + R11A8.5(+) + sir-2.1(+)]}, CF1038 [daf-16(mu86)], AA86 [daf-12(rh61rh411)], DR1572 [daf-2(e1368)], unknown strain; genotype: [daf-7(e1372); daf-3(e1376)], PS6025 {qrIs2 [sra-9::mCasp1]}, unknown strain; genotype: {daf-37; unc-119; mEx187[gpa-4p::daf-37, unc-119(+)]}, unknown strain; genotype: [daf-37(DR2585)], unknown strain; genotype: {daf-37; unc-119; mEx188[srbc-64p::daf-37,unc-119(+)]}, unknown strain; genotype: {daf-37; mIs41[daf-37p::daf-37,rol-6(su1006)]}, DR62 [daf-7(m62)], CB1372 [daf-7(e1372)], CB1376 [daf-3(e1376)]
84 Ascarosides ascr#3 35 / 3 N2 (wild type), VC199 [sir-2.1(ok434)], unknown strain {daf-16(mgDf50); unc-119(ed3); pkIs1642[unc-119(+) + R11A8.5(+) + sir-2.1(+)]}, CF1038 [daf-16(mu86)], AA86 [daf-12(rh61rh411)], DR1572 [daf-2(e1368)], unknown strain; genotype: [daf-7(e1372); daf-3(e1376)], DR62 [daf-7(m62)], CB1372 [daf-7(e1372)], CB1376 [daf-3(e1376)]
85 Aspalathin (16752601) 13 / 4 N2 (wild type), TK22 [mev-1(kn1)], TJ375 {gpIs1 [hsp-16.2p::GFP]}
86 Aspirin (2244) 21 / 10 N2 (wild type), CF1038 [daf-16(mu86)], CB1370 [daf-2(e1370)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, DA1116 [eat-2(ad1116)], VC199 [sir-2.1(ok434)], MQ887 [isp-1(qm150)], CB4876 [clk-1(e2519)], RB754 [aak-2(ok524)], KK184 [par-4(it47)], CF1903 [glp-1(e2144)], AA86 [daf-12(rh61rh411)], AA89 [daf-12(rh274)], CF1880 [glp-1(e2141); daf-16(mu86)], CF2248 {glp-1(e2141); daf-12(rh61rh411); daf-16(mu86); muEx158 [daf-16AM::GFP + sur-5p::GFP]}, unknown strain; genotype: [glp-1(e2141); daf-12(rh61rh411)]
87 Astragalan (Astragalus membranaceus polysaccharide) (103026223) 23 / 3 AM141 {rmIs133 [unc-54p::Q40::YFP]}, HA759 {rtIs11 [osm-10p::GFP + osm-10p::HtnQ150 + dpy-20(+)]}, N2 (wild type), CB1370 [daf-2(e1370)], TJ1052 [age-1(hx546)], DR26 [daf-16(m26)]
88 Ayurvedic polyherbal extract (includes 6 herbs: B. aristata roots, C.rotundus rhizome, C. deodara stem bark, E. officinalisfruits, T. chebula fruits and T. bellirica fruits) 19 / 14 N2 (wild type), TK22 [mev-1(kn1)], DA1116 [eat-2(ad1116)], PS3551 [hsf-1(sy441)], GR1307 [daf-16(mgDf50)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], CB1370 [daf-2(e1370)], CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}
89 Açaí extract (Euterpe oleracea Mart.) 43 / 19 BA17 [fem-1(hc17)], N2 (wild type), LD1171 {ldIs3 [gcs-1p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CF1038 [daf-16(mu86)], VC8 [jnk-1(gk7)], AU3 [nsy-1(ag3)], KU4 [sek-1(km4)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], MT2605 [unc-43(n498n1186)], AM1 [osr-1(rm1)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, VP198 {kbIs5 [gpdh-1p::GFP + rol-6(su1006)]}, unknown strain [vha-6::Q44::YFP], TK22 [mev-1(kn1)], TJ375 {gpIs1 [hsp-16.2p::GFP]}, GR1307 [daf-16(mgDf50)]
90 BMS-754807 (24785538) 4 / 1 CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
91 BRL 15572 (3654103) 1 / 2 N2 (wild type)
92 BRL 50481 (2921148) 1 / 2 N2 (wild type)
93 BTCP hydrochloride (11957484) 1 / 2 N2 (wild type)
94 Bacopa monnieri, hexane extract 19 / 3 N2 (wild type)
95 Bacopa monnieri aqueous extract 9 / 9 N2 (wild type), TK22 [mev-1(kn1)], CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
96 Baicalein (5281605) 10 / 6 N2 (wild type), CF1038 [daf-16(mu86)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
97 Balm leaves extract (Melissa officinalis) 1 / 1 N2 (wild type)
98 ß-Estradiol (5757) 1 / 2 N2 (wild type)
99 Bilobalide (73581) 1 / 2 N2 (wild type)
100 Black tea extract (Camellia sinensis) 9 / 9 N2 (wild type), TK22 [mev-1(kn1)], VC199 [sir-2.1(ok434)]
101 Black tea leaves extract (Camellia sinensis) 1 / 1 N2 (wild type)
102 Blackberry leaves extract (Rubus fruticosus) 1 / 1 N2 (wild type)
103 Bletilla striata polysaccharide 4 / 6 N2 (wild type), unknown strain [daf-16 deletion mutant]
104 Blueberry (Vaccinium angustifolium) anthocyanin fraction (135310604) 2 / 2 BA17 [fem-1(hc17)]
105 Blueberry (Vaccinium angustifolium) crude extract (135310604) 1 / 1 BA17 [fem-1(hc17)]
106 Blueberry (Vaccinium angustifolium) polyphenol fraction (135310604) 14 / 8 BA17 [fem-1(hc17)], GR1307 [daf-16(mgDf50)], TK22 [mev-1(kn1)], VC199 [sir-2.1(ok434)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], AM1 [osr-1(rm1)], AU1 [sek-1(ag1)], MT2605 [unc-43(n498n1186)]
107 Blueberry (Vaccinium angustifolium) proanthocyanidin fraction (135310604) 2 / 2 BA17 [fem-1(hc17)]
108 Brazilin (from Caesalpinia sappan) (73384) 6 / 12 N2 (wild type), CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
109 Buckwheat trypsin inhibitor (recombinant) 8 / 17 N2 (wild type), CF1038 [daf-16(mu86)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, DA2123 {adls2122 [lgg-1p::GFP::lgg-1 + rol-6(su1006)]}, DR1572 [daf-2(e1368)]
110 Caesalpinia sappan L. (ethyl acetate fraction) 1 / 1 N2 (wild type)
111 Caesalpinia sappan L. (methanol extract) 1 / 1 N2 (wild type)
112 Caesalpinia sappan L. (methylene chloride fraction) 1 / 1 N2 (wild type)
113 Caesalpinia sappan L. (n-butanol fraction) 1 / 1 N2 (wild type)
114 Caffeic acid phenethylester (5281787) 9 / 7 N2 (wild type), LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CF1038 [daf-16(mu86)]
115 Calycophyllum spruceanum, water extract 22 / 9 N2 (wild type), CF1038 [daf-16(mu86)], GR1307 [daf-16(mgDf50)], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, TJ375 {gpIs1 [hsp-16.2p::GFP]}, BA17 [fem-1(hc17)]
116 Calycosin (5280448) 12 / 6 N2 (wild type), GR1307 [daf-16(mgDf50)], CB1370 [daf-2(e1370)], TJ1052 [age-1(hx546)], DA1116 [eat-2(ad1116)], MT2605 [unc-43(n498n1186)], EU35 [skn-1(zu169)/nT1 [unc-?(n754) let-?]], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, unknown strain [SKN-1::GFP]
117 Camellia tenuifolia seed oil 4 / 3 N2 (wild type), GR1307 [daf-16(mgDf50)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
118 Camomile flowers extract (Matricaria chamomilla) 1 / 1 N2 (wild type)
119 Carqueja hydroalcoholic extract 31 / 16 N2 (wild type), BA17 [fem-1(hc17)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], CF1038 [daf-16(mu86)], AU3 [nsy-1(ag3)], KU4 [sek-1(km4)], VC8 [jnk-1(gk7)], AM1 [osr-1(rm1)], KU25 [pmk-1(km25)], MH37 [mpk-1(ku1); unc-32(e189)], MT2605 [unc-43(n498n1186)], LD1171 {ldIs3 [gcs-1p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, SJ4005 {zcIs4 [hsp-4::GFP]}, CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}
120 Caryophyllene oxide (from Cinnamomum osmophloeum Leaves) (1742210) 1 / 1 N2 (wild type)
121 Catalpol (91520) 14 / 15 N2 (wild type), CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], VC199 [sir-2.1(ok434)], GR1307 [daf-16(mgDf50)], DR1572 [daf-2(e1368)], TJ1052 [age-1(hx546)], FK171 [mek-1(ks54)]
122 (±) Catechin (9064) 27 / 12 N2 (wild type), TJ1052 [age-1(hx546)], VC204 [akt-2(ok393)], DR20 [daf-12(m20)], GR1307 [daf-16(mgDf50)], VC8 [jnk-1(gk7)], TK22 [mev-1(kn1)], AE501 [nhr-8(ok186)], AM1 [osr-1(rm1)], VC199 [sir-2.1(ok434)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], MT2605 [unc-43(n498n1186)], DR1567 [daf-2(m577)], AU1 [sek-1(ag1)], DA465 [eat-2(ad465)]
123 Catechinic acid 21 / 10 N2 (wild type), SJ4103 {zcIs14 [myo-3::GFP(mit)]}, SJ4143 {zcIs17 [ges-1::GFP(mit)]}, SJ4100 {zcls13 [hsp-6::GFP]}
124 Cerium oxide nanoparticles (73963) 9 / 7 N2 (wild type), CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, SJ4005 {zcIs4 [hsp-4::GFP]}
125 Chlorogenic acid (1794427) 27 / 8 BA17 [fem-1(hc17)], N2 (wild type), DA1116 [eat-2(ad1116)], VC199 [sir-2.1(ok434)], MQ887 [isp-1(qm150)], CB4876 [clk-1(e2519)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], PS3551 [hsf-1(sy441)], CB1370 [daf-2(e1370)], CF1038 [daf-16(mu86)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, JT9609 [pdk-1(sa680)], RB759 [akt-1(ok525)], VC204 [akt-2(ok393)], VC345 [sgk-1(ok538)], CF1903 [glp-1(e2144)], ZG31 [hif-1(ia4)]
126 Chlorprothixene hydrochloride (5282478) 1 / 2 N2 (wild type)
127 Cinnamomum osmophloeum leaves extract (essential oils) 4 / 1 N2 (wild type)
128 Cinnamon bark extract 1 / 2 N2 (wild type)
129 Cinnarizine (1547484) 1 / 2 N2 (wild type)
130 Citalopram (2771) 5 / 2 CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
131 Coffee seeds extract (1794427) 1 / 1 N2 (wild type)
132 Cola seeds extract 1 / 1 N2 (wild type)
133 Cortexolone maleate (6604000) 1 / 2 N2 (wild type)
134 Cranberry extract (Vaccinium macrocarpon) (135331993) 26 / 13 N2 (wild type), GR1307 [daf-16(mgDf50)], VC199 [sir-2.1(ok434)], AM1 [osr-1(rm1)], AU1 [sek-1(ag1)], MT2605 [unc-43(n498n1186)], CB1370 [daf-2(e1370)], VC8 [jnk-1(gk7)], TJ1052 [age-1(hx546)], GR1352 {daf-16(mgDf47); xrIs87 [daf-16(alpha)::GFP::daf-16B + rol-6(su1006)]}, CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}
135 Cranberry extract standardized to 4.0% proanthocyanidins 17 / 5 N2 (wild type), AU1 [sek-1(ag1)], KU25 [pmk-1(km25)], CB1370 [daf-2(e1370)], TJ1052 [age-1(hx546)], GR1307 [daf-16(mgDf50)], PS3551 [hsf-1(sy441)], VC1668 [fmo-2(ok2147)], RB1573 [dod-22(ok1918)], CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
136 Curcumin (969516) 25 / 10 N2 (wild type), TK22 [mev-1(kn1)], CB1370 [daf-2(e1370)], TJ1052 [age-1(hx546)], GR1310 [akt-1(mg144)], GR1318 [pdk-1(mg142)], GR1307 [daf-16(mgDf50)], AM1 [osr-1(rm1)], MT2605 [unc-43(n498n1186)], AU1 [sek-1(ag1)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], VC199 [sir-2.1(ok434)], FK171 [mek-1(ks54)], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}, CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CL2122 {dvIs15 [(pPD30.38) unc-54(vector) + (pCL26) mtl-2::GFP]}, CL2355{smg-1(cc546); dvIs50 [pCL45 (snb-1::Abeta 1-42::3' UTR(long) + mtl-2::GFP]}, NL5901 {pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]}
137 Cyanidin-3-sambubiosid (6602304) 3 / 1 N2 (wild type)
138 Cyclosporin A (5284373) 1 / 2 N2 (wild type)
139 Cyproterone acetate (9880) 1 / 2 N2 (wild type)
140 Cysteine (5862) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
141 DAPH (1697) 1 / 2 N2 (wild type)
142 3-(3,4-Dichlorophenyl)-1,1-dimethylurea (DCMU) (3120) 8 / 3 N2 (wild type)
143 3,3-Diethyl-2-pyrrolidinon (DEABL) (9793807) 1 / 2 N2 (wild type)
144 DETA NONOate (NO donor) (135402056) 1 / 1 N2 (wild type)
145 DMF (Dimethyl formamide) (6228) 17 / 12 N2 (wild type), DR1572 [daf-2(e1368)], TJ1052 [age-1(hx546)], DR26 [daf-16(m26)], CF1139[daf-16(mu86); muIs61 [(pKL78) daf16::GFP + rol-6(su1006)]], CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, CL4176 (dvIs27[myo-3::Ab3–42 let 39UTR(pAF29);pRF4 (rol-6(su1006))])
146 DMSO (Dimethyl sulfoxide) (679) 18 / 12 N2 (wild type), DR1572 [daf-2(e1368)], TJ1052 [age-1(hx546)], DR26 [daf-16(m26)], CF1139[daf-16(mu86); muIs61 [(pKL78) daf16::GFP + rol-6(su1006)]], CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, CL4176 (dvIs27[myo-3::Ab3–42 let 39UTR(pAF29);pRF4 (rol-6(su1006))])
147 Danazol (28417) 1 / 2 N2 (wild type)
148 Delphinidin-3-sambubiosid (10196837) 3 / 1 N2 (wild type)
149 Demeclocycline hydrochloride (54686764) 1 / 2 N2 (wild type)
150 Diallyldisulfide (16590) 2 / 3 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, N2 (wild type)
151 Diallylsulfide (11617) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
152 Diallyltrisulfide (16315) 2 / 3 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, N2 (wild type)
153 Diamide (5353800) 4 / 3 N2 (wild type), TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
154 Dibromoacetic acid (12433) 6 / 10 N2 (wild type)
155 Dichloroacetate (DCA) (25975) 2 / 11 N2 (wild type)
156 Diethyl maleate (5271566) 16 / 6 N2 (wild type), EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], CF1038 [daf-16(mu86)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
157 Dihydroergocristine methanesulfonate (444034) 1 / 2 N2 (wild type)
158 Dihydroergotamine methanesulfonate (71171) 1 / 2 N2 (wild type)
159 Diplocyclos palmatus, methanolic leaf extract 5 / 5 N2 (wild type)
160 Doxazosin mesylate (62978) 1 / 2 N2 (wild type)
161 Doxycycline hydrochloride (54685920) 1 / 2 N2 (wild type)
162 Epigallocatechin gallate (EGCG) (65064) 45 / 17 N2 (wild type), GR1307 [daf-16(mgDf50)], CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, TJ375 {gpIs1 [hsp-16.2p::GFP]}, BA17 [fem-1(hc17)], TK22 [mev-1(kn1)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}, EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1038 [daf-16(mu86)], LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}
163 EPs7630 (Pelargonium sidoides root extract) 6 / 2 TJ375 {gpIs1 [hsp-16.2p::GFP]}, N2 (wild type)
164 Elderberry juice (Sambucus nigra) 1 / 2 N2 (wild type)
165 Eleutherococcus senticosus root extract 15 / 8 N2 (wild type), TK22 [mev-1(kn1)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
166 Eliprodil (60703) 1 / 2 N2 (wild type)
167 Ellagic acid (5281855) 9 / 11 N2 (wild type), TK22 [mev-1(kn1)], DA465 [eat-2(ad465)]
168 Endopleura uchi, water extract 22 / 8 N2 (wild type), BA17 [fem-1(hc17)], CF1038 [daf-16(mu86)], GR1307 [daf-16(mgDf50)], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, TJ375 {gpIs1 [hsp-16.2p::GFP]}, AM141 {rmIs133 [unc-54p::Q40::YFP]}
169 Erchen wan (TCM formula) 6 / 5 TK22 [mev-1(kn1)], N2 (wild type)
170 Ethosuximide (3291) 60 / 14 N2 (wild type), DR26 [daf-16(m26)], CF1038 [daf-16(mu86)], CB1370 [daf-2(e1370)], unknown strain [unc-31(e928)], CB246 [unc-64(e246)], unknown strain [aex-3(ad418)], PR802 [osm-3(p802)], PR801 [che-3(p801)], unknown strain [che-3(am165)]
171 FUdR (5-fluoro 2-deoxyuridine) (3363) 23 / 6 HE250 [unc-52(e669su250)], CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, AM141 {rmIs133 [unc-54p::Q40::YFP]}, N2 (wild type), CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, CB4037 [glp-1(e2141)], AA86 [daf-12(rh61rh411)], CF1038 [daf-16(mu86)], BX165 [nhr-80(tm1011)], PS3551 [hsf-1(sy441)], BA17 [fem-1(hc17)], CB3844 [fem-3(e2006)], CB3844 [fem-3(e2006)]; mated, BA24 [fer-1(hc24)], BA6 [fer-6(hc6)], BA671 [spe-9(hc88)]
172 Fermented Rooibos leaves extract (Aspalathus linearis) 1 / 2 N2 (wild type)
173 Flavonoid fraction of EGb 761 (64927) 1 / 2 CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
174 Fluoxetine (3386) 10 / 5 CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, N2 (wild type), unknown strain [daf-16 deletion mutant]
175 Folic acid (135398658) 16 / 13 N2 (wild type), TK22 [mev-1(kn1)], DA1116 [eat-2(ad1116)], GR1307 [daf-16(mgDf50)], VC199 [sir-2.1(ok434)], EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}
176 Gallic acid (370) 8 / 11 N2 (wild type), TK22 [mev-1(kn1)], DA465 [eat-2(ad465)]
177 Geldanamycin (5288382) 2 / 3 N2 (wild type), DA465[eat-2(ad465)]
178 Genistein (5280961) 6 / 11 N2 (wild type), CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
179 Ginkgo biloba leaf extract EGb 761 (64927) 12 / 11 N2 (wild type), TK22 [mev-1(kn1)], CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, PD4251 {dpy-20(e1282); ccIs4251 [(pSAK2) myo-3p::GFP::LacZ::NLS + (pSAK4) myo-3p::mitochondrial GFP + dpy-20(+)]}, CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CL2355 {smg-1(cc546); dvIs50 [pCL45 (snb-1::Abeta 1-42::3' UTR(long) + mtl-2::GFP]}
180 Ginkgolide B (65243) 1 / 2 N2 (wild type)
181 Ginseng roots extract (Panax ginseng) 1 / 1 N2 (wild type)
182 Glochidion zeylanicum, hexane extract 21 / 10 N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], BA17 [fem-1(hc17)]
183 Glochidion zeylanicum, methanol extract 21 / 10 N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], BA17 [fem-1(hc17)]
184 Glycerol (753) 2 / 3 N2 (wild type)
185 Glycyrrhiza glabra (licorice) roots, ethanolic extract 8 / 3 N2 (wild type), SS104 [glp-4(bn2)]
186 Glycyrrhizae radix extract (643903) 7 / 12 N2 (wild type), CF1038 [daf-16(mu86)], genotype: oxIs12[Ex(Punc-47:GFP)]
187 Gracilaria lemaneiformis polysaccharide 9 / 9 N2 (wild type), AM141 {rmIs133 [unc-54p::Q40::YFP]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
188 Green Paraguay tea leaves extract (Ilex paraguariensis) 1 / 1 N2 (wild type)
189 Green rooibus extract (Aspalathus linearis) 4 / 4 N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}
190 Guanabenz acetate (5702062) 1 / 2 N2 (wild type)
191 Guanfacine hydrochloride (71401) 1 / 2 N2 (wild type)
192 Hedyotis diffusa, N-butanol extract 18 / 14 N2 (wild type), CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}, CL2355 {smg-1(cc546); dvIs50 [pCL45 (snb-1::Abeta 1-42::3' UTR(long) + mtl-2::GFP]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
193 Hexahydro-sila-difenidol hydrochloride (4155031) 1 / 2 N2 (wild type)
194 Hibiscus calyces extract (Hibiscus sabdariffa) 1 / 2 N2 (wild type)
195 Hidrox® 5 / 9 N2 (wild type), OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}, UA44 {baIn11 [dat-1p::α-synuclein, dat-1p::GFP]}
196 Holothuria leucospilota, aqueous extract 8 / 2 N2 (wild type)
197 Holothuria leucospilota, ethanol extract 10 / 8 N2 (wild type)
198 Holothuria leucospilota, n-butanol extract 20 / 4 N2 (wild type), TJ1052 [age-1(hx546)], CF1038 [daf-16(mu86)], VC199 [sir-2.1(ok434)], VC8 [jnk-1(gk7)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
199 Huanshao dan (TCM formula) 6 / 5 TK22 [mev-1(kn1)], N2 (wild type)
200 Icariin (5318997) 6 / 3 N2 (wild type), AM140 {rmIs132 [unc-54p::Q35::YFP]}, CB1370 [daf-2(e1370)], CF1038 [daf-16(mu86)]
201 Icariside I (5745470) 1 / 1 N2 (wild type)
202 Icariside II (5488822) 14 / 8 N2 (wild type), PD4251 {dpy-20(e1282); ccIs4251 [(pSAK2) myo-3p::GFP::LacZ::NLS + (pSAK4) myo-3p::mitochondrial GFP + dpy-20(+)]}, AM140 {rmIs132 [unc-54p::Q35::YFP]}, CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CB1370 [daf-2(e1370)], CF1038 [daf-16(mu86)], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, DA1116 [eat-2(ad1116)], PS3551 [hsf-1(sy441)], XA8223 [rsks-1(ok1255)]
203 Icaritin (5318980) 1 / 1 N2 (wild type)
204 Ilex paraguariensis, hydroalcoholic extract 14 / 6 N2 (wild type), CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}
205 Isomitraphylline 3 / 2 N2 (wild type)
206 Isosilybin A (11059920) 1 / 1 N2 (wild type)
207 Isoxanthohumol (513197) 14 / 5 N2 (wild type), CF1038 [daf-16(mu86)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
208 Jiaogulan leaves extract (Gynostemma pentaphyllum) 1 / 1 N2 (wild type)
209 Kaempferol (5280863) 1 / 2 N2 (wild type)
210 Kenpaullone (3820) 1 / 2 N2 (wild type)
211 Ketanserin tartrate (135348) 1 / 2 N2 (wild type)
212 Knotgrass herb extract (Polygonum aviculare) 1 / 1 N2 (wild type)
213 Korean mistletoe (Viscum album coloratum) water extract 4 / 4 N2 (wild type)
214 L-Ascorbic acid (Vitamin C) (54670067) 2 / 3 CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, N2 (wild type)
215 L-Bornyl acetate (from Cinnamomum osmophloeum Leaves) (131752808) 1 / 1 N2 (wild type)
216 L-Dopa (6047) 1 / 1 NL5901 {pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]}
217 LFM-A13 (54676905) 1 / 2 N2 (wild type)
218 LY-367,265 (4605800) 1 / 2 N2 (wild type)
219 LY294002 (3973) 9 / 5 N2 (wild type), TJ1052 [age-1(hx546)], DA465[eat-2(ad465)]
220 Lappaol C (323896) 12 / 5 N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, GR1307 [daf-16(mgDf50)], TK22 [mev-1(kn1)]
221 Lappaol F (73425459) 12 / 5 N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, GR1307 [daf-16(mgDf50)], TK22 [mev-1(kn1)]
222 Liangyi Gao (TCM) 3 / 11 N2 (wild type), CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
223 Lime blossom flowers extract (Tilia spp.) 1 / 1 N2 (wild type)
224 Lithium chloride (433294) 2 / 7 JK1107 [glp-1(q224)], DA2123 {adls2122 [lgg-1p::GFP::lgg-1 + rol-6(su1006)]}
225 Liuwei dihuang wan (ethanol extract) 8 / 8 CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}, N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}
226 Liuwei dihuang wan (TCM formula; water extract) 5 / 2 CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, TJ375 {gpIs1 [hsp-16.2p::GFP]}
227 Liuwei dihuang wan (TCM formula) 6 / 5 TK22 [mev-1(kn1)], N2 (wild type)
228 Lonidamine (39562) 3 / 5 N2 (wild type), KU25 [pmk-1(km25)]
229 Loratadine (3957) 1 / 2 N2 (wild type)
230 Loxapine succinate (71399) 1 / 2 N2 (wild type)
231 M084 (n-butyl-[1H]-benzimidazol-2-amine) (284016) 14 / 6 N2 (wild type), DA1116 [eat-2(ad1116)], VC199 [sir-2.1(ok434)], MQ887 [isp-1(qm150)], CB4876 [clk-1(e2519)], CB1370 [daf-2(e1370)], CF1038 [daf-16(mu86)], JT9609 [pdk-1(sa680)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], RB754 [aak-2(ok524)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
232 MAHMA NONOate (NO donor) (135487863) 16 / 3 N2 (wild type), PS3551 [hsf-1(sy441)], CF1038 [daf-16(mu86)], MQ130 [clk-1(qm30)], TJ375 {gpIs1 [hsp-16.2p::GFP]}, AM446 {rmIs223 [C12C8.1::GFP]}, OH8 [ttx-3(mg158)], IK597 [gcy-23(nj37); gcy-8(oy44); gcy-18(nj38)]
233 3ß-Methoxy-pregnenolone (MAP4343) (134159554) 43 / 3 ID1 {igIs1 [mec-3p::htt57-128Q::CFP; lin-15(+); mec-7p::YFP]}, ID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}, ID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}, unnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}, DR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}, EW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}, RB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}
234 Matairesinol (119205) 12 / 5 N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, GR1307 [daf-16(mgDf50)], TK22 [mev-1(kn1)]
235 Menadione (4055) 4 / 3 N2 (wild type), TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
236 Metergoline (28693) 1 / 2 N2 (wild type)
237 Methyl 7-Oxo-7H-pyrido[1, 2, 3-cd]perimidine-9-caboxylate 4 / 4 N2 (wild type)
238 Methylergonovine maleate (5281072) 1 / 2 N2 (wild type)
239 Mianserin hydrochloride (68551) 1 / 2 N2 (wild type)
240 Minocycline hydrochloride (54685925) 1 / 2 N2 (wild type)
241 Mitraphylline 3 / 2 N2 (wild type)
242 Manganese sulfate (MnSO4) (24580) 16 / 5 N2 (wild type), TK22 [mev-1(kn1)]
243 Momordica saponin extract 7 / 13 N2 (wild type), TK22 [mev-1(kn1)], GR1307 [daf-16(mgDf50)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], PS3551 [hsf-1(sy441)], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
244 Monascin (from red mold dioscorea) (12118082) 9 / 7 N2 (wild type), GR1307 [daf-16(mgDf50)], CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
245 Mulberry leaf polyphenols 16 / 5 N2 (wild type), CF1038 [daf-16(mu86)], AA86 [daf-12(rh61rh411)], BX165 [nhr-80(tm1011)], SM190 [smg-1(cc546); pha-4(zu225)], VC199 [sir-2.1(ok434)], CF1903 [glp-1(e2144)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], TK22 [mev-1(kn1)]
246 Mytilus edulis, protein hydrolyzate (5282253) 3 / 8 N2 (wild type)
247 N-(2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl)-3-methoxybenzamide (3626837) 1 / 2 N2 (wild type)
248 N-Nitrosodimethylamine (6124) 6 / 10 N2 (wild type)
249 N6-Benzyladenine (62389) 3 / 3 BA17 [fem-1(hc17)]
250 N6-Isopentenyladenine (92180) 3 / 3 BA17 [fem-1(hc17)]
251 NG-094 15 / 8 AM134 {rmIs126 [unc-54p::Q0::YFP]}, AM140 {rmIs132 [unc-54p::Q35::YFP]}, BC10060 {dpy-5(e907); sEx884 [rCesC12C8.1::GFP + pCeh361]}
252 NT219 15 / 8 N2 (wild type), CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, BC10061 {sEx888 [hsp-70p (c12c8.1)::GFP]}, CF512 [fer-15(b26); fem-1(hc17)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}, unknown strain; genotype: [polyQ40::YFP], unknown strain {polyQ35::YFP}
253 Naftopidil dihydrochloride (11957660) 1 / 2 N2 (wild type)
254 Nicardipine hydrochloride (41114) 1 / 2 N2 (wild type)
255 Nitrendipine (4507) 1 / 2 N2 (wild type)
256 Nortriptyline hydrochloride (441358) 1 / 2 N2 (wild type)
257 Nymphaea hybrid (total flavones) 1 / 3 N2 (wild type)
258 Nymphaea hybrid root extract 5 / 6 N2 (wild type), CF1038 [daf-16(mu86)]
259 O-acetyl glucomannan 3 / 11 N2 (wild type)
260 O-allylserine (54195890) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
261 Oat 24 / 2 N2 (wild type), GR1307 [daf-16(mgDf50)], VC199 [sir-2.1(ok434)], GA158 [daf-16(mgDf50); daf-2(m65)]
262 Ocimum sanctum crude extract 8 / 4 N2 (wild type)
263 Oleanolic acid (10494) 8 / 6 N2 (wild type), GR1307 [daf-16(mgDf50)], VC199 [sir-2.1(ok434)], DA1116 [eat-2(ad1116)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
264 Oleic acid (445639) 2 / 3 N2 (wild type), TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
265 Oligonol 3 / 1 CF512 [fer-15(b26); fem-1(hc17)]
266 Orange extract 6 / 12 N2 (wild type)
267 Otophylloside B (10079485) 17 / 8 N2 (wild type), DA1116 [eat-2(ad1116)], VC199 [sir-2.1(ok434)], CB4876 [clk-1(e2519)], CB1370 [daf-2(e1370)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CF1038 [daf-16(mu86)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}, CL2122 {dvIs15 [(pPD30.38) unc-54(vector) + (pCL26) mtl-2::GFP]}, CL2355{smg-1(cc546); dvIs50 [pCL45 (snb-1::Abeta 1-42::3' UTR(long) + mtl-2::GFP]}
268 Oxatomide (4615) 1 / 2 N2 (wild type)
269 PAPP/LY-165,163 (121930) 1 / 2 N2 (wild type)
270 PBT2 (10016012) 1 / 1 AM140 {rmIs132 [unc-54p::Q35::YFP]}
271 Panax notoginseng branch roots polysaccharides 5 / 7 N2 (wild type)
272 Panax notoginseng fibrous roots polysaccharides 5 / 7 N2 (wild type)
273 Panax notoginseng main roots polysaccharides 5 / 7 N2 (wild type)
274 paroxetine (43815) 5 / 2 CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}
275 pentagalloyl glucose from Eucalyptus leaves (65238) 11 / 10 N2 (wild type), GR1307 [daf-16(mgDf50)], TJ1052 [age-1(hx546)], DA1116 [eat-2(ad1116)], VC199 [sir-2.1(ok434)], MQ887 [isp-1(qm150)], TK22 [mev-1(kn1)], MQ130 [clk-1(qm30)]
276 Pergolide methanesulfonate (47812) 1 / 2 N2 (wild type)
277 Piceatannol (667639) 20 / 9 N2 (wild type), GR1307 [daf-16(mgDf50)], CB1370 [daf-2(e1370)], TJ1052 [age-1(hx546)], VC199 [sir-2.1(ok434)], MQ130 [clk-1(qm30)], DA1116 [eat-2(ad1116)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
278 Pinoresinol (73399) 7 / 5 N2 (wild type), TK22 [mev-1(kn1)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
279 Platycladus orientalis extract (n-butanol extract from seed) 5 / 7 N2 (wild type), CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
280 Polydatin (5281718) 10 / 6 N2 (wild type), CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}
281 Polygonum multiflorum extract (135281013) 31 / 11 N2 (wild type), CF1038 [daf-16(mu86)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, VC199 [sir-2.1(ok434)], LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}
282 Proanthocyanidin (108065) 1 / 5 N2 (wild type)
283 Promethazine hydrochloride (6014) 1 / 2 N2 (wild type)
284 Propionylpromazine hydrochloride (24351) 1 / 2 N2 (wild type)
285 protocatechuic acid (72) 6 / 18 N2 (wild type)
286 Psammaplysene A (11434210) 5 / 2 ZB1102 {glt-3(bz34); nuIs5 [glr-1::GFP + glr-1::G(alpha)s(Q227L) + lin-15(+)]}, KP742 {nuIs5 [glr-1::gfp; glr-1::Gs(Q227L); lin-15 (+)]}, ZB2283 {Pmyo-3:daf-16::gfp}
287 Psora-4 (6603977) 1 / 2 N2 (wild type)
288 Qibao meiran dan (TCM formula) 5 / 5 TK22 [mev-1(kn1)], N2 (wild type)
289 Qinjiao wan (TCM formula) 5 / 5 TK22 [mev-1(kn1)], N2 (wild type)
290 Quercetin (5280343) 15 / 12 N2 (wild type), CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1038 [daf-16(mu86)], CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}
291 Quinidine sulfate (441326) 1 / 2 N2 (wild type)
292 Rapamycin (5284616) 5 / 4 N2 (wild type), VC199 [sir-2.1(ok434)], DA465[eat-2(ad465)], GR1307 [daf-16(mgDf50)]
293 Rechtsregulat® 4 / 7 N2 (wild type)
294 Red mold dioscorea (ethanol extract) 8 / 4 N2 (wild type), GR1307 [daf-16(mgDf50)], CF1038 [daf-16(mu86)], TK22 [mev-1(kn1)], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
295 Red rooibus extract (Aspalathus linearis) 4 / 4 N2 (wild type), TJ375 {gpIs1 [hsp-16.2p::GFP]}
296 Resveratrol (445154) 42 / 21 N2 (wild type), VC199 [sir-2.1(ok434)], RB754 [aak-2(ok524)], CF1038 [daf-16(mu86)], TJ375 {gpIs1 [hsp-16.2p::GFP]}, TK22 [mev-1(kn1)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
297 Rhodiola root extract (Rhodiola rosea) 1 / 1 N2 (wild type)
298 Rhodiola rosea L root extract 15 / 8 N2 (wild type), TK22 [mev-1(kn1)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
299 Ribes fasciculatum (ethylacetate fraction) 12 / 10 N2 (wild type), CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, GR1307 [daf-16(mgDf50)], VC199 [sir-2.1(ok434)], AM1 [osr-1(rm1)], DR1572 [daf-2(e1368)], TJ1052 [age-1(hx546)], FK171 [mek-1(ks54)]
300 Rosmarinus officinalis L. (ethanolic extract) (65126) 12 / 6 N2 (wild type), TK22 [mev-1(kn1)], CB1370 [daf-2(e1370)], CF1038 [daf-16(mu86)], PS3551 [hsf-1(sy441)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
301 S-1-propenylcysteine (67153752) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
302 S-allylcysteine (9793905) 19 / 17 N2 (wild type), CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, unknown strain [daf-16(mgDf47)], LD1482 {daf-16(mu86); Is[DAF-16A::GFP]}, CL691 {dvIs19 [(pAF15) gst-4p::GFP::NLS]; skn-1(zu67) IV/nT1 [unc-?(n754) let-?]}, EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}, KU4 [sek-1(km4)]
303 S-allylcysteine sulfoxide (Alliin) (121922) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
304 S-allylhomocysteine (9793905) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
305 S-allylmercaptocysteine (9794159) 19 / 17 N2 (wild type), CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, unknown strain [daf-16(mgDf47)], LD1482 {daf-16(mu86); Is[DAF-16A::GFP]}, CL691 {dvIs19 [(pAF15) gst-4p::GFP::NLS]; skn-1(zu67) IV/nT1 [unc-?(n754) let-?]}, EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}, KU4 [sek-1(km4)]
306 S-allylmercaptohomocysteine (9794159) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
307 S-ethylcysteine (92185) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
308 S-ethylcysteine sulfoxide (Ethiin) (146416) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
309 S-methylcysteine (24417) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
310 S-methylcysteine sulfoxide (Methiin) (82142) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
311 S-methylmercaptocysteine 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
312 S-n-butenylcysteine (90773413) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
313 S-n-butylcysteine (9574102) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
314 S-n-propylcysteine (101975) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
315 S-n-propylmercaptocysteine (192762) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
316 SU 4312 (6450842) 1 / 2 N2 (wild type)
317 Salicylamine (70267) 9 / 6 N2 (wild type), VC199 [sir-2.1(ok434)], RB981 [ets-7(ok888)]
318 Sesame cake peptides 8 / 11 N2 (wild type), TK22 [mev-1(kn1)], DA465 [eat-2(ad465)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], PS3551 [hsf-1(sy441)], CF1038 [daf-16(mu86)]
319 Shengmai yin (TCM formula) 5 / 5 TK22 [mev-1(kn1)], N2 (wild type)
320 Shiquan dabu wan (TCM formula) 5 / 5 TK22 [mev-1(kn1)], N2 (wild type)
321 Silybin A/B (3086637) 1 / 1 N2 (wild type)
322 Silychristin A/B (441764) 1 / 1 N2 (wild type)
323 Silydianin A/B (11982272) 1 / 1 N2 (wild type)
324 Silymarin (31553) 7 / 4 N2 (wild type), CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}
325 Sophora moorcroftiana, extract decoction 1 / 8 N2 (wild type)
326 Sophora moorcroftiana, polysaccharides 3 / 8 N2 (wild type)
327 Soybean trypsin inhibitor (49777573) 3 / 2 N2 (wild type)
328 Succinimide (11439) 7 / 3 N2 (wild type)
329 T-cadinol (from Cinnamomum osmophloeum Leaves) (160799) 1 / 1 N2 (wild type)
330 TSG (2,3,5,4󸀠-Tetrahydroxystilbene-2-O-𝛽-D-glucoside) from Polygonum multiflorum (5321884) 6 / 7 N2 (wild type), CF1038 [daf-16(mu86)], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
331 Tamarixetin (5281699) 1 / 2 N2 (wild type)
332 Tannic acid (16129878) 35 / 12 N2 (wild type), TJ1052 [age-1(hx546)], VC204 [akt-2(ok393)], DR20 [daf-12(m20)], GR1307 [daf-16(mgDf50)], VC8 [jnk-1(gk7)], TK22 [mev-1(kn1)], AE501 [nhr-8(ok186)], AM1 [osr-1(rm1)], VC199 [sir-2.1(ok434)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], MT2605 [unc-43(n498n1186)], DR1567 [daf-2(m577)], AU1 [sek-1(ag1)], DA465 [eat-2(ad465)]
333 Taxifolin (439533) 9 / 7 N2 (wild type), CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, unknown strain [cyp-35::GFP]
334 Thioridazine hydrochloride (66062) 1 / 2 N2 (wild type)
335 Tianma wan (TCM formula) 5 / 5 TK22 [mev-1(kn1)], N2 (wild type)
336 Tomatidine (65576) 8 / 9 N2 (wild type), EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]]
337 Trequinsin hydrochloride (3060974) 1 / 2 N2 (wild type)
338 Trichostatin A (444732) 5 / 3 N2 (wild type), DA465[eat-2(ad465)], GR1307 [daf-16(mgDf50)]
339 Trimethadione (5576) 20 / 9 N2 (wild type), DR26 [daf-16(m26)], CF1038 [daf-16(mu86)], CB1370 [daf-2(e1370)], unknown strain [unc-31(e928)], CB246 [unc-64(e246)], unknown strain [aex-3(ad418)], PR678 [tax-4(p678)], PR802 [osm-3(p802)], DA465 [eat-2(ad465)]
340 Trolox (40634) 11 / 7 N2 (wild type), CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, unknown strain [cyp-35::GFP]
341 Tunicamycin (11104835) 2 / 1 N2 (wild type), VC199 [sir-2.1(ok434)]
342 Tyrosine (6057) 1 / 2 N2 (wild type)
343 Tyrosol (10393) 19 / 16 DH26 [fer-15(b26)], N2 (wild type), TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, TK22 [mev-1(kn1)], VC199 [sir-2.1(ok434)], GM11 [daf-16(m26); fer-15(b26)], GM6 [fer-15(b26); daf-2(e1370)], PS3551 [hsf-1(sy441)], NL5901 {pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]}, UA44 {baIn11 [dat-1p::α-synuclein, dat-1p::GFP]}
344 Tyrphostin AG 1478 (2051) 1 / 2 N2 (wild type)
345 Uncaria tomentosa, aqueous leaf extract 20 / 6 N2 (wild type), EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1038 [daf-16(mu86)], TJ375 {gpIs1 [hsp-16.2p::GFP]}
346 Urolithin A (5488186) 37 / 14 N2 (wild type), CF1038 [daf-16(mu86)], DA465 [eat-2(ad465)], RB754 [aak-2(ok524)], TK22 [mev-1(kn1)], CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, SJ4005 {zcIs4 [hsp-4::GFP]}, SJ4100 {zcIs13 [hsp-6::GFP]}, SJ4143 {zcIs17 [ges-1::GFP(mit)]}, SJ4103 {zcIs14 [myo-3::GFP(mit)]}, VC1024 [pdr-1 (gk448)], DA2123 {adls2122 [lgg-1p::GFP::lgg-1 + rol-6(su1006)]}
347 Urolithin B (5380406) 1 / 3 N2 (wild type)
348 Urolithin C (5482042) 1 / 3 N2 (wild type)
349 Urolithin D (5482042) 1 / 3 N2 (wild type)
350 Ursolic acid (3β-Hydroxy-urs-12-en-28-oic acid) (64945) 24 / 16 N2 (wild type), GR1307 [daf-16(mgDf50)], VC8 [jnk-1(gk7)], KU2 [jkk-1(km2)], FK171 [mek-1(ks54)], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CB1370 [daf-2(e1370)], PS3551 [hsf-1(sy441)], DA1116 [eat-2(ad1116)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], JK1521 [fog-2(q71); pha-4(q490)/stu-3 (q265); rol-9 (sc148)], VC199 [sir-2.1(ok434)], TK22 [mev-1(kn1)], AM141 {rmIs133 [unc-54p::Q40::YFP]}, NL5901 {pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]}
351 Vaccinum uliginosum, Alaskan bog blueberry anthocyanin fraction 1 / 1 OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}
352 Vaccinum uliginosum, Alaskan bog blueberry proanthocyanidin fraction 1 / 1 OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}
353 Vaccinum uliginosum, Alaskan bog blueberry crude extract 10 / 6 OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}
354 Verminoside (12000883) 11 / 7 N2 (wild type), TK22 [mev-1(kn1)], GR1307 [daf-16(mgDf50)], CB1370 [daf-2(e1370)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}
355 Vincristine sulfate (249332) 1 / 2 N2 (wild type)
356 Vinpocetine (443955) 1 / 2 N2 (wild type)
357 Vitexin (from Vigna angularis) (5280441) 6 / 12 N2 (wild type), CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
358 Wheat gluten hydrolysate (135305709) 3 / 8 N2 (wild type)
359 Wisconsin Ginseng extract from Panax quinquefolius 4 / 5 PD4251 {dpy-20(e1282); ccIs4251 [(pSAK2) myo-3p::GFP::LacZ::NLS + (pSAK4) myo-3p::mitochondrial GFP + dpy-20(+)]}, N2 (wild type)
360 Withanolide A (11294368) 21 / 20 N2 (wild type), TK22 [mev-1(kn1)], DA1116 [eat-2(ad1116)], VC345 [sgk-1(ok538)], PS3551 [hsf-1(sy441)], GR1307 [daf-16(mgDf50)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, NL5901 {pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]}, JG337 {let-23(sy1); jgls[let-23N::hEGFR-C; rol-6d]}, JG324 {sqt-1(jg52); jgls6 [let-23::hEGFR-TK(L858R); rol-6d]}, JG388 {sqt-1(jg52); jgls25 [let-23::hEGFR-TK(T790M-L858R); rol-6d; myo2::mCherry]}
361 metformin + phenformin 1 / 1 N2 (wild type)
362 α,α-Trehalose (7427) 22 / 9 N2 (wild type), unknown strain; genotype: [polyQ40::YFP], CB1370 [daf-2(e1370)], DR1572 [daf-2(e1368)], GR1309 [daf-16(mgDf47); daf-2(e1370)], unknown strain [daf-16(mgDf47)], CB1372 [daf-7(e1372)]
363 α,β-Trehalose (10871590) 1 / 2 N2 (wild type)
364 α-Tocopherol (14985) 3 / 3 N2 (wild type)
365 α-lipoic acid (864) 17 / 13 N2 (wild type), CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, unknown strain [cyp-35::GFP], GR1307 [daf-16(mgDf50)], CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}
366 Ascarosides ascr#3 ascr#2 mixture 9 / 3 N2 (wild type)
367 Beta-carotene 1 / 2 N2 (wild type)
368 ß-Caryophyllene (5281515) 15 / 12 N2 (wild type), TK22 [mev-1(kn1)], DA1116 [eat-2(ad1116)], GR1307 [daf-16(mgDf50)], VC199 [sir-2.1(ok434)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, LD1 {ldIs7 [skn-1b/c::GFP + rol-6(su1006)]}
369 Beta-cryptoxanthin 9 / 2 N2 (wild type)
370 Beta-cryptoxanthin in non-saponified carotenoid extract from mandarin juice 1 / 1 N2 (wild type)
371 Beta-cryptoxanthin in saponified carotenoid extract from mandarin juice 1 / 1 N2 (wild type)
372 Blueberry extract (347910769) 9 / 12 N2 (wild type)
373 Boeravinone B (14018348) 17 / 15 N2 (wild type), TK22 [mev-1(kn1)], CW152 [gas-1(fc21)], CB1370 [daf-2(e1370)], TJ1052 [age-1(hx546)], GR1307 [daf-16(mgDf50)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], KU4 [sek-1(km4)], RB754 [aak-2(ok524)], DA1116 [eat-2(ad1116)], CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
374 caffeine 14 / 6 N2 (wild type), CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}
375 Carnosol 11 / 16 N2 (wild type), GR1307 [daf-16(mgDf50)], PS3551 [hsf-1(sy441)], CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, AM140 {rmIs132 [unc-54p::Q35::YFP]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
376 catalpol-ginsenoside Rg1 mixture (1:1) 1 / 8 N2 (wild type)
377 Chicoric acid 18 / 10 N2 (wild type), RB754 [aak-2(ok524)], CB1370 [daf-2(e1370)], DA1116 [eat-2(ad1116)], GR1307 [daf-16(mgDf50)], EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], TJ1052 [age-1(hx546)], LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}
378 cis-(Z)-Flupenthixol dihydrochloride (10140115) 1 / 2 N2 (wild type)
379 Cis-zeatin (688597) 3 / 3 BA17 [fem-1(hc17)]
380 d-Allulose (441036) 15 / 4 N2 (wild type), DA1116 [eat-2(ad1116)], GR1307 [daf-16(mgDf50)], VC199 [sir-2.1(ok434)], RB754 [aak-2(ok524)], unknown strain; genotype: [skn-1(tm4241)]
381 Dextrin 4 / 3 N2 (wild type), GR1307 [daf-16(mgDf50)]
382 Dihydrozeatin (32021) 3 / 3 BA17 [fem-1(hc17)]
383 Dipeptide Tyr-Ala (4078684) 4 / 10 N2 (wild type), CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}
384 Echinacoside 7 / 6 N2 (wild type), GR1307 [daf-16(mgDf50)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
385 Enoxacin (3229) 21 / 10 N2 (wild type), DR26 [daf-16(m26)], EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], CB4876 [clk-1(e2519)], RB754 [aak-2(ok524)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, SJ4005 {zcIs4 [hsp-4::GFP]}, SJ4100 {zcls13 [hsp-6::GFP]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, PD8753 {dcr-1(ok247); hT2 [bli-4(e937) let-?(q782) qIs48]}, VC446 [alg-1(gk214)], WM49 [rde-4(ne301)], VC347 [mir-57(gk175)], MT16848 [mir-249(n4983)], VC328 [mir-47(gk167)], VC1051 [mir-34(gk437)], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, BB4 [adr-1(gv6); adr-2(gv42)]
386 Fermented rice with Lactobacillus kefiranofaciens; dextrin included 4 / 3 N2 (wild type), GR1307 [daf-16(mgDf50)]
387 Fermented rice with Lactobacillus kefiranofaciens; without dextrin 6 / 3 N2 (wild type), GR1307 [daf-16(mgDf50)]
388 Ginkgolide A 1 / 1 CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}
389 Ginsenoside Rg1 1 / 8 N2 (wild type)
390 Glutaredoxin from recombinant buckwheat (9501) 8 / 11 N2 (wild type), PS3551 [hsf-1(sy441)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], CF1038 [daf-16(mu86)], CB1370 [daf-2(e1370)], TJ1052 [age-1(hx546)]
391 Hydroxytyrosol 6 / 10 N2 (wild type), OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}, UA44 {baIn11 [dat-1p::α-synuclein, dat-1p::GFP]}
392 Isoquercitrin (5280804) 1 / 2 ID1 {igIs1 [mec-3p::htt57-128Q::CFP; lin-15(+); mec-7p::YFP]}
393 Kinetin (3830) 7 / 5 N2 (wild type), BA17 [fem-1(hc17)], CF1038 [daf-16(mu86)]
394 Laricitrin (5282154) 6 / 10 N2 (wild type), CF1038 [daf-16(mu86)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
395 Lycopene 1 / 2 N2 (wild type)
396 Maltose (6255) 1 / 2 N2 (wild type)
397 Meta-topolin (11557770) 2 / 3 BA17 [fem-1(hc17)]
398 metformin 72 / 11 N2 (wild type), RB755 [metr-1(ok521)], RB2240 [sams-1(ok3033)], GA1001 [aak-2(ok524)], EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], GR1307 [daf-16(mgDf50)], TJ1052 [age-1(hx546)], CB1370 [daf-2(e1370)], DA1116 [eat-2(ad1116)], RB754 [aak-2(ok524)], MR507 [aak-2(rr48)], KK184 [par-4(it47)], KK300 [par-4(it57)], LD1 {ldIs7 [skn-1b/c::GFP + rol-6(su1006)]}, LG348 {skn-1(zu135)/nT1[qIs51];geIs9[gpa-4p::skn-1b::gfp; rol-6(su1006)]}, LG357 {skn-1(zu135)/nT1[qIs51];geIs10[ges-1p::skn-1c::gfp; rol-6(su1006)]}, CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
399 Methacycline (54675785) 4 / 3 N2 (wild type), CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}, unknown strain; genotype: [lin-15(n765ts), unc119p::ATX3Q17::GFP], unknown strain; genotype: [lin-15(n765ts), unc119p::ATX3Q130::GFP]
400 Myricetin (5281672) 4 / 2 N2 (wild type), CF2732 [sir-2.1(ok434)], CF1038 [daf-16(mu86)], CF2725 [aak-2(ok524)]
401 Myricetintrimethylether (5481248) 6 / 10 N2 (wild type), CF1038 [daf-16(mu86)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
402 Naringenin 5 / 3 N2 (wild type)
403 Naringin 5 / 3 N2 (wild type)
404 Nobiletin 6 / 14 N2 (wild type)
405 17ß-Oestradiol (5991) 43 / 3 ID1 {igIs1 [mec-3p::htt57-128Q::CFP; lin-15(+); mec-7p::YFP]}, ID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}, ID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}, unnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}, DR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}, EW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}, RB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}
406 Oleuropein aglycone 6 / 10 N2 (wild type), OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}, UA44 {baIn11 [dat-1p::α-synuclein, dat-1p::GFP]}
407 Orlistat 1 / 1 N2 (wild type)
408 Ortho-topolin (13506406) 2 / 3 BA17 [fem-1(hc17)]
409 p-Coumaric acid (637542) 14 / 11 N2 (wild type), GR1307 [daf-16(mgDf50)], EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
410 Para-topolin (101234914) 2 / 3 BA17 [fem-1(hc17)]
411 Peony (Paeonia suffruticosa) petal extract 3 / 1 N2 (wild type)
412 phenformin 10 / 5 N2 (wild type), GA1001 [aak-2(ok524)], EU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]], CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, GA1112 {aak-2(ok524); dvIs19 [pAF15 (gst-4::GFP::NLS)]}
413 Phycoerythrin (SID: 53788505) 2 / 2 N2 (wild type), CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}
414 Phytol 1 / 2 N2 (wild type)
415 propyl gallate (4947) 9 / 7 N2 (wild type), CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, unknown strain [cyp-35::GFP]
416 Raspberry, acetone extract 12 / 8 N2 (wild type), CB1370 [daf-2(e1370)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
417 Rosmarinic acid 10 / 18 N2 (wild type), CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, AM140 {rmIs132 [unc-54p::Q35::YFP]}, GR1307 [daf-16(mgDf50)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
418 Selegiline (26757) 1 / 1 NL5901 {pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]}
419 Sesamin (72307) 5 / 5 N2 (wild type), CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CL2355 {smg-1(cc546); dvIs50 [pCL45 (snb-1::Abeta 1-42::3' UTR(long) + mtl-2::GFP]}
420 Sesamol (68289) 5 / 5 N2 (wild type), CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CL2355 {smg-1(cc546); dvIs50 [pCL45 (snb-1::Abeta 1-42::3' UTR(long) + mtl-2::GFP]}
421 Sesamolin (101746) 5 / 5 N2 (wild type), CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}, CL2355 {smg-1(cc546); dvIs50 [pCL45 (snb-1::Abeta 1-42::3' UTR(long) + mtl-2::GFP]}
422 spermidine 19 / 6 N2 (wild type), VC174 [wrn-1(gk99)], NL5901 {pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]}, UM0001 {smg-1(cc546); dvIs50 [pCL45 (snb-1::Abeta 1-42::3' UTR(long) + mtl-2::GFP]; byIs161 [rab-3p::F3(delta)K280 + myo-2p::mCherry]
423 Sucrose (5988) 1 / 2 N2 (wild type)
424 Syringetin (5281953) 6 / 10 N2 (wild type), CF1038 [daf-16(mu86)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
425 Tambulin 14 / 13 N2 (wild type), unknown strain [daf-16 deletion mutant], NL5901 {pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]}, CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}, TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}
426 Tanespimycin 12 / 3 N2 (wild type), TJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]}
427 Tart cherry extract 11 / 2 N2 (wild type), unknown strain [daf-16 deletion mutant], unknown strain [aak-2 deletion mutant]
428 Tetracycline (4675776) 3 / 1 N2 (wild type), CL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}, unknown strain; genotype: [lin-15(n765ts), unc119p::ATX3Q130::GFP]
429 Trans-2,4,5-trihydroxystilbene 7 / 7 N2 (wild type), CF1038 [daf-16(mu86)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], VC199 [sir-2.1(ok434)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}
430 Trans-2,5-dimethoxy-4-hydroxystilbene 1 / 1 N2 (wild type)
431 Trans-3,5-dimethoxy-4-fluoro-4-hydroxystilbene 7 / 7 N2 (wild type), CF1038 [daf-16(mu86)], EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]], VC199 [sir-2.1(ok434)], TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}, LD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}
432 Trans-3,5-dimethoxy-4-hydroxystilbene 1 / 1 N2 (wild type)
433 Trans-4-hydroxy-3,4,5-trifluorostilbene 1 / 1 N2 (wild type)
434 Trans-zeatin (449093) 3 / 3 BA17 [fem-1(hc17)]
435 Trans‐communic acid 8 / 4 N2 (wild type), VC199 [sir-2.1(ok434)], DR26 [daf-16(m26)]
436 trimethoprim 6 / 1 N2 (wild type), GA1001 [aak-2(ok524)]
437 trimethoprim + metformin 4 / 1 N2 (wild type)
438 Zymolytic grain extract 5 / 8 N2 (wild type)
439 α-Cadinol (from Cinnamomum osmophloeum Leaves) (10398656) 1 / 1 N2 (wild type)
440 β-Sitosterol (222284) 1 / 1 N2 (wild type)
441 β-Amyrin (73145) 8 / 5 N2 (wild type), NL5901 {pkIs2386 [unc-54p::alphasynuclein::YFP + unc-119(+)]}, BZ555 {egIs1 [dat-1p::GFP]}, DA2123 {adls2122 [lgg-1p::GFP::lgg-1 + rol-6(su1006)]}
442 γ -Glutamyl-S-allylcysteine (11346811) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
443 γ -Glutamyl-S-allylmercaptocysteine (101630431) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}
444 γ -Glutamyl-S-methylcysteine (13894650) 1 / 1 CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}

See details of selected compounds

End of Table