Compound ID 122   (prev - next)

Name: (±) Catechin (9064) (edit)

30 entries:
Treatment(±) Catechinphysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)9064ChEMBLCHEMBL206452pharyngeal pumpingbody length / growth ratenumber of offspringvertex (progeny per day)quantity of early reproductiononset of egg layingheat stress resistanceoxidative stress resistancetriglyceride / fat / lipid contentantioxidative capacitymedian lifespanmean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
100 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°Cup11.24n.d.up8.39yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CupyesA3, A6 & A9down-6,35yesA6up3.6nononenoup8.6yesA6; Stressor: 35°C for 8 h; endpoint: survivalup17.33yesA6; Stressor: 0.8 mM H2O2 for 8 h; endpoint: survivalup13.27n.d.up8.87yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
300 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°Cup9.56n.d.up5.86yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMstart: parental generation; stop: A6OP50NGM agarN2 (wild type)20°Cup2.81n.d.up1.13noSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)15°Cup14.19n.d.up14.68yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)23°Cup8.95n.d.up10.92yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50 until A6; from A6: OP50, heat-inactivatedNGM agarAmpicillinN2 (wild type)20°Cup5.88n.d.up7.81yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarTJ1052 [age-1(hx546)]23°Cup6.19n.d.up11.05yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarVC204 [akt-2(ok393)]20°Cup4.15n.d.up2.79noSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarDR20 [daf-12(m20)]20°Cup6.05n.d.up9.49yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarGR1307 [daf-16(mgDf50)]20°Cup6.12n.d.up6.21yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarVC8 [jnk-1(gk7)]20°Cup5.20n.d.up5.59yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarTK22 [mev-1(kn1)]20°Cup1.30n.d.up0.7noSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarAE501 [nhr-8(ok186)]20°Cup4.20n.d.up1.98noSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarAM1 [osr-1(rm1)]20°Cup17.64n.d.up13.7yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarVC199 [sir-2.1(ok434)]20°Cup4.50n.d.up5.88yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarEU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]]20°Cup2.48n.d.up11.73yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarMT2605 [unc-43(n498n1186)]20°Cup3.60n.d.up3.99yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarDR1567 [daf-2(m577)]23°Cup3.95n.d.up0.21noSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
200 µMwhole life; start: parental generationOP50NGM agarAU1 [sek-1(ag1)]15°Cup10.84n.d.up11.16yesSaul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CEW (2009): Catechin induced longevity in C. elegans: From key regulator genes to disposable soma. Mech Ageing Dev. 130, 477-486no
100 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CnonenoA6; Stressor: 35°C for 8 h; endpoint: survivalupnoA6; Stressor: 0.8 mM H2O2 for 8 h; endpoint: survivalupyesSaul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720. no
200 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CupA3, A6, and A9downyesA6nonenononenononeyesupyesA6; Stressor: 35°C for 8 h; endpoint: survivalupyesA6; Stressor: 0.8 mM H2O2 for 8 h; endpoint: survivaldownnoA1nonenoA1upyesSaul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720. no
300 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CupnoA6; Stressor: 35°C for 8 h; endpoint: survivalupyesA6; Stressor: 0.8 mM H2O2 for 8 h; endpoint: survivalupyesSaul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720. no
400 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CupnoA6; Stressor: 35°C for 8 h; endpoint: survivalupyesA6; Stressor: 0.8 mM H2O2 for 8 h; endpoint: survivalupyesSaul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720. no
800 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CupnoA6; Stressor: 35°C for 8 h; endpoint: survivalupyesA6; Stressor: 0.8 mM H2O2 for 8 h; endpoint: survivalupyesSaul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720. no
200 µMwhole life; start: parental generationOP50NGM agarTK22 [mev-1(kn1)]20°CnonenoSaul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720. no
200 µMwhole life; start: parental generationOP50NGM agarDA465 [eat-2(ad465)]20°CnonenoSaul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720. no