Compound ID 124   (prev - next)

Name: Cerium oxide nanoparticles (73963) (edit)

12 entries:
TreatmentCerium oxide nanoparticlesphysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)73963ChEMBLbody length / growth ratenumber of offspringvertex (progeny per day)heat stress resistanceactivity / quantity / expression of HSPsactivity / quantity / expression of GSTsmean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
0.172 μg/mLwhole life; start: L4OP50-1NGM agarN2 (wild type)20°CnonenoRogers S, Rice KM, Manne ND, Shokuhfar T, He K, Selvaraj V, Blough ER (2015) Cerium oxide nanoparticle aggregates affect stress response and function in Caenorhabditis elegans. SAGE Open Med 3, 2050312115575387.
1.72 μg/mLwhole life; start: L4OP50-1NGM agarN2 (wild type)20°CnonenoGST-4 and HSP-4Rogers S, Rice KM, Manne ND, Shokuhfar T, He K, Selvaraj V, Blough ER (2015) Cerium oxide nanoparticle aggregates affect stress response and function in Caenorhabditis elegans. SAGE Open Med 3, 2050312115575387.
17.21 μg/mLwhole life; start: L4OP50-1NGM agarN2 (wild type)20°CnonenoRogers S, Rice KM, Manne ND, Shokuhfar T, He K, Selvaraj V, Blough ER (2015) Cerium oxide nanoparticle aggregates affect stress response and function in Caenorhabditis elegans. SAGE Open Med 3, 2050312115575387.
0.172 μg/mLwhole life; start: L4OP50-1NGM agarCL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}20°CnonenoA2, A4, and A6downyesdownyesdownnoA3; stressor: 35°C for 8 h; endpoint: survivalupyesA6; no significant change at A2 and A4Rogers S, Rice KM, Manne ND, Shokuhfar T, He K, Selvaraj V, Blough ER (2015) Cerium oxide nanoparticle aggregates affect stress response and function in Caenorhabditis elegans. SAGE Open Med 3, 2050312115575387.
1.72 μg/mLwhole life; start: L4OP50-1NGM agarCL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}20°CdownyesA2; no significant change at A6 and A4downyesdownyesdownnoA3; stressor: 35°C for 8 h; endpoint: survivalupyesA2 and A6; no significant change at A4Rogers S, Rice KM, Manne ND, Shokuhfar T, He K, Selvaraj V, Blough ER (2015) Cerium oxide nanoparticle aggregates affect stress response and function in Caenorhabditis elegans. SAGE Open Med 3, 2050312115575387.
17.21 μg/mLwhole life; start: L4OP50-1NGM agarCL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}20°CdownyesA2; no significant change at A6 and A4downyesdownyesnonenoA3; stressor: 35°C for 8 h; endpoint: survivalupyesA2 and A6; no significant change at A4Rogers S, Rice KM, Manne ND, Shokuhfar T, He K, Selvaraj V, Blough ER (2015) Cerium oxide nanoparticle aggregates affect stress response and function in Caenorhabditis elegans. SAGE Open Med 3, 2050312115575387.
0.172 μg/mLwhole life; start: L4OP50-1NGM agarSJ4005 {zcIs4 [hsp-4::GFP]}20°CnonenoA2, A4, and A6downnodownnodownyesA3; stressor: 35°C for 8 h; endpoint: survivalupyesA2; no significant change at A4 and A6Rogers S, Rice KM, Manne ND, Shokuhfar T, He K, Selvaraj V, Blough ER (2015) Cerium oxide nanoparticle aggregates affect stress response and function in Caenorhabditis elegans. SAGE Open Med 3, 2050312115575387.
1.72 μg/mLwhole life; start: L4OP50-1NGM agarSJ4005 {zcIs4 [hsp-4::GFP]}20°CdownyesA6; no significant change at A2 and A4downnodownnodownyesA3; stressor: 35°C for 8 h; endpoint: survivalupyesA2 and A6; no significant change at A4Rogers S, Rice KM, Manne ND, Shokuhfar T, He K, Selvaraj V, Blough ER (2015) Cerium oxide nanoparticle aggregates affect stress response and function in Caenorhabditis elegans. SAGE Open Med 3, 2050312115575387.
17.21 μg/mLwhole life; start: L4OP50-1NGM agarSJ4005 {zcIs4 [hsp-4::GFP]}20°CdownyesA6; no significant change at A2 and A4downnodownnodownyesA3; stressor: 35°C for 8 h; endpoint: survivalupyesA2, A4, and A6Rogers S, Rice KM, Manne ND, Shokuhfar T, He K, Selvaraj V, Blough ER (2015) Cerium oxide nanoparticle aggregates affect stress response and function in Caenorhabditis elegans. SAGE Open Med 3, 2050312115575387.