Compound ID 145   (prev - next)

Name: DMF (Dimethyl formamide) (6228) (edit)

20 entries:
TreatmentDMF (Dimethyl formamide)cognitive functionphysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)6228ChEMBLchemotaxispharyngeal pumpinglocomotion on solid medianumber of offspringreproductive total spanonset of egg layingheat stress resistanceoxidative stress resistanceoxidative stress resistanceactivity / quantity / expression of HSPstranslocation of DAF-16 to nucleusmedian lifespanmaximum lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
0.5 %whole life; start: egg stageOP50liquid S-mediumN2 (wild type)20°Cup37.50yesup56.25n.d.Frankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.75 %whole life; start: egg stageOP50liquid S-mediumN2 (wild type)20°CupyesA2nonenodaily measuremets; monitoring of intake of fluorescent beedsdown-35.09yesupn.d.delayedn.d.downyesA3; Stressor: 35°C for 19 hdownnoA2; Stressor: 1 mM H2O2 for 12 h; endpoint: median lifespandownyesA2; Stressor: 40 mM paraquat for 44 h; endpoint: median lifespanup32.25yesup54.68n.d.Frankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
1 %whole life; start: egg stageOP50liquid S-mediumN2 (wild type)20°Cup33.33yesup33.33n.d.Frankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
1.5 %whole life; start: egg stageOP50liquid S-mediumN2 (wild type)20°Cdownn.d.downn.d.Frankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.75 %whole life; start: end of egg-laying periodOP50liquid S-mediumN2 (wild type)20°Cnonenoup25.71n.d.Frankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.75 %whole life; start: egg stageOP50liquid S-mediumDR1572 [daf-2(e1368)]20°Cdownn.d.up45.00yesup57.00n.d.Frankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.75 %whole life; start: egg stageOP50liquid S-mediumTJ1052 [age-1(hx546)]20°Cdownn.d.up59.00yesup75.00n.d.Frankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.75 %whole life; start: egg stageOP50liquid S-mediumDR26 [daf-16(m26)]20°Cup40.00yesup43.00n.d.Frankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.75 %whole life; start: egg stageOP50liquid S-mediumCF1139[daf-16(mu86); muIs61 [(pKL78) daf16::GFP + rol-6(su1006)]]20°Cnonen.d.measurements at several timepointsFrankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.75 %whole life; start: egg stagelow-concentrated OP50 (DR conditions)liquid S-mediumN2 (wild type)20°Cdownn.d.delayedn.d.up53.00yesup54.00n.d.Frankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.75 %2 h; start: A2OP50liquid S-mediumN2 (wild type)20°CupyesA2; Stressor: 1 mM H2O2 for 12 h; endpoint: median lifespannonenoA2; Stressor: 40 mM paraquat for 44 h; endpoint: median lifespanFrankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.75 %whole life; start: egg stageOP50liquid S-mediumCL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}20°Cnonen.d.A3; measured via fluorescenceFrankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.05 %whole life; start: L3OP50NGM agarCL4176 (dvIs27[myo-3::Ab3–42 let 39UTR(pAF29);pRF4 (rol-6(su1006))])25°CupnoFrankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.1 %whole life; start: L3OP50NGM agarCL4176 (dvIs27[myo-3::Ab3–42 let 39UTR(pAF29);pRF4 (rol-6(su1006))])25°CupnoFrankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.25 %whole life; start: L3OP50NGM agarCL4176 (dvIs27[myo-3::Ab3–42 let 39UTR(pAF29);pRF4 (rol-6(su1006))])25°CupyesFrankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
0.5 %whole life; start: L3OP50NGM agarCL4176 (dvIs27[myo-3::Ab3–42 let 39UTR(pAF29);pRF4 (rol-6(su1006))])25°CupyesFrankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.
1 %whole life; start: L3OP50NGM agarCL4176 (dvIs27[myo-3::Ab3–42 let 39UTR(pAF29);pRF4 (rol-6(su1006))])25°CupyesFrankowski H, Alavez S, Spilman P, Mark KA, Nelson JD, Mollahan P, Rao RV, Chen SF, Lithgow GJ, Ellerby HM (2013) Dimethyl sulfoxide and dimethyl formamide increase lifespan of C. elegans in liquid. Mech Ageing Dev 134, 69-78.