Compound ID 154   (prev - next)

Name: Dibromoacetic acid (12433) (edit)

9 entries:
TreatmentDibromoacetic acidphysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)12433ChEMBLCHEMBL449362pharyngeal pumpingbody length / growth ratenumber of offspringvertex (progeny per day)heat stress resistanceMDA levelmedian lifespanmean lifespanmaximum lifespanminimum lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
50 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CupnoA6upyesA6nonenononenononenoA1; stressor: 35°C; endpoint: survivaldownnoA1up6.57n.d.up7.65yesup6.59n.d.up12.57n.d.down-regulation of cep-1, rad-51, hsp-16.1, hsp-70, gst-4, gst-38, gstk-1, cyp-35A2, and sod-1Baberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no
100 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CupnoA6upyesA6up15.82n.d.up14.57yesup0.76n.d.up38.21n.d.Baberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no
0.1 mMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CnonenononenononenoA1; stressor: 35°C; endpoint: survivaldown-regulation of cep-1, egl-1, rad-51, hsp-16.1, hsp-70, gst-38, gstk-1, cyp-35A2, sod-5, and sod-1Baberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no
0.5 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CnonenononenononenoA1; stressor: 35°C; endpoint: survivalBaberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no
2 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CnonenononenononenoA1; stressor: 35°C; endpoint: survivalBaberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no
10 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CnonenononenononenoA1; stressor: 35°C; endpoint: survivalBaberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no