Compound ID 163 (prev - next)

Name: EPs7630 (Pelargonium sidoides root extract) (edit)

9 entries:

Treatment	EPs7630 (Pelargonium sidoides root extract)						physiological function				healthspan biomarkers				Target	Reference
CID (PubChem)		ChEMBL					oxidative stress resistance				activity / quantity / expression of HSPs
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
40 µg/ml	whole life; start: L1	OP50	liquid S-medium		TJ375 {gpIs1 [hsp-16.2p::GFP]}	20°C					down	-32.30	yes	A1; pre-exposed to 20 µM juglone for 24 h; measured via fluorescence		Rezaizadehnajafi L, Wink M (2014) EPs7630(®) from Pelargonium sidoides increases stress resistance in Caenorhabditis elegans probably via the DAF-16/FOXO pathway. Phytomedicine 21, 547-550.
50 µg/ml	whole life; start: L1	OP50	liquid S-medium		TJ375 {gpIs1 [hsp-16.2p::GFP]}	20°C					down		yes	A1; pre-exposed to 20 µM juglone for 24 h; measured via fluorescence	insulin/IGF-1signaling pathway	Rezaizadehnajafi L, Wink M (2014) EPs7630(®) from Pelargonium sidoides increases stress resistance in Caenorhabditis elegans probably via the DAF-16/FOXO pathway. Phytomedicine 21, 547-550.
100 µg/ml	whole life; start: L1	OP50	liquid S-medium		TJ375 {gpIs1 [hsp-16.2p::GFP]}	20°C					down	58.50	yes	A1; pre-exposed to 20 µM juglone for 24 h; measured via fluorescence		Rezaizadehnajafi L, Wink M (2014) EPs7630(®) from Pelargonium sidoides increases stress resistance in Caenorhabditis elegans probably via the DAF-16/FOXO pathway. Phytomedicine 21, 547-550.
40 µg/ml	whole life; start: L1	OP50	liquid S-medium		N2 (wild type)	20°C	up	22.30	yes	A1; Stressor: 300 µM juglone for 24 h; endpoint: survival						Rezaizadehnajafi L, Wink M (2014) EPs7630(®) from Pelargonium sidoides increases stress resistance in Caenorhabditis elegans probably via the DAF-16/FOXO pathway. Phytomedicine 21, 547-550.
50 µg/ml	whole life; start: L1	OP50	liquid S-medium		N2 (wild type)	20°C	up	24.00	yes	A1; Stressor: 300 µM juglone for 24 h; endpoint: survival						Rezaizadehnajafi L, Wink M (2014) EPs7630(®) from Pelargonium sidoides increases stress resistance in Caenorhabditis elegans probably via the DAF-16/FOXO pathway. Phytomedicine 21, 547-550.
100 µg/ml	whole life; start: L1	OP50	liquid S-medium		N2 (wild type)	20°C	up		yes	A1; Stressor: 300 µM juglone for 24 h; endpoint: survival						Rezaizadehnajafi L, Wink M (2014) EPs7630(®) from Pelargonium sidoides increases stress resistance in Caenorhabditis elegans probably via the DAF-16/FOXO pathway. Phytomedicine 21, 547-550.