Compound ID 170 (prev - next)

Name: Ethosuximide (3291) (edit)

63 entries:

Treatment	Ethosuximide						physical function																reproductive function																								lifespan																Reference
CID (PubChem)	3291	ChEMBL					fast pharyngeal pumping span				pharyngeal total span				locomotion on solid media				fast body movement span				number of offspring				reproductive total span				vertex (progeny per day)				reproductive growth span				quantity of late reproduction				speed of larval development				median lifespan				mean lifespan				survival at a given time point				maximum lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
2 mg/ml	whole life; start: L4	OP50	NGM agar		N2 (wild type)	20°C																	up	2.30	no	ferilized by males	up	12.20	yes	ferilized by males	down	-5.22	no	ferilized by males	up	33.33	no	ferilized by males	up	600.00	yes	Progeny after day 9; mated on days 1 & 2 or on day 10																					Hughes SE, Evason K, Xiong C, Kornfeld K (2007) Genetic and pharmacological factors that influence reproductive aging in nematodes. PLoS Genet. 3, e25
2 mg/ml	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C	up	3.70	no		up	27.12	yes		up		yes	measured as body bends per minute	up	34.15	yes						down	-3.45	no	self-fertile													down	-67.42	n.d.						up	13.00	yes						up	24.00	yes		Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
4 mg/ml	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																																													up	17.00	yes						up	22.00	yes		Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
4 mg/ml	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	15°C																																													up	35.00	yes						up	37.00	yes		Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
4 mg/ml	whole life; start: parental generation	OP50, UV-inactivated	NGM agar		N2 (wild type)	20°C																																													up	14.00	yes						down	-2.00	no		Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
2 mg/ml	whole life; start: parental generation	OP50	NGM agar		DR26 [daf-16(m26)]	20°C																																													up	16.00	yes						up	7.00	yes		Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
0.5 mg/ml	whole life; start: parental generation	OP50	NGM agar		CF1038 [daf-16(mu86)]	20°C																																													up	11.00	yes						up	8.00	yes		Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
4 mg/ml	whole life; start: parental generation	OP50	NGM agar		CB1370 [daf-2(e1370)]	20°C																																													up	14.00	yes						up	8.00	yes		Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
2 mg/ml	whole life; start: parental generation	OP50	NGM agar		unknown strain [unc-31(e928)]	20°C																																													up	20.00	yes						up	23.00	yes		Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
2 mg/ml	whole life; start: parental generation	OP50	NGM agar		CB246 [unc-64(e246)]	20°C																																													up	8.00	yes						up	2.00	yes		Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
4 mg/ml	whole life; start: parental generation	OP50	NGM agar		unknown strain [aex-3(ad418)]	20°C																																													up	13.00	yes						up	18.00	yes		Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
2 mg/ml	whole life; start: parental generation	OP50	NGM agar		PR802 [osm-3(p802)]	20°C																																													up	9.00	no						up	6.00	no		Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
10 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	15°C																																									up	24.00	no														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	15°C																																									up	29.00	yes														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	15°C																																									down	-57.00	yes														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	15°C																																									down	-57.00	yes														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																									up	11.00	no						none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																					down		n.d.		up	11.00	yes						none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
5 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																																	none		n.d.	A7					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																									down	-58.00	yes	Toxicity is proportional to duration of UV-treatment of ethosuximide					down		n.d.	A7 and 5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
50 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																																	down		n.d.	A7					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
5 mM (heat-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																																	none		n.d.	A7					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM (heat-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																																	none		n.d.	A7					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
50 mM (heat-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																																	none		n.d.	A7					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
5 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																																	none		n.d.	A7					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																																	none		n.d.	A7					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
50 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																																	none		n.d.	A7					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																					down		n.d.		down	-58.00	yes						down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	25°C																																									down	-12.00	no														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	25°C																																									down	-24.00	yes														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	25°C																																									down	-71.00	yes														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	25°C																																									down	-88.00	yes														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM	whole life; start: L4	OP50, heat-inactivated until L4; from A1: no food	NGM agar	FUDR; ampicillin	N2 (wild type)	15°C																																									up	6.67	yes														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM	whole life; start: L4	OP50, heat-inactivated until L4; from A1: no food	NGM agar	FUDR; ampicillin	N2 (wild type)	15°C																																									up	6.67	yes														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, heat-inactivated until L4; from A1: no food	NGM agar	FUDR; ampicillin	N2 (wild type)	15°C																																									down	-86.67	yes														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, heat-inactivated until L4; from A1: no food	NGM agar	FUDR; ampicillin	N2 (wild type)	15°C																																									down	-86.67	yes														Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
70 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																																	none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
80 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
85 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	N2 (wild type)	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR802 [osm-3(p802)]	20°C																																																	none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR802 [osm-3(p802)]	20°C																																																	none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
70 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR802 [osm-3(p802)]	20°C																																																	none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
80 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR802 [osm-3(p802)]	20°C																																																	none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
85 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR802 [osm-3(p802)]	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR801 [che-3(p801)]	20°C																																																	none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR801 [che-3(p801)]	20°C																																																	none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
70 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR801 [che-3(p801)]	20°C																																																	none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
80 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR801 [che-3(p801)]	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
85 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR801 [che-3(p801)]	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	unknown strain [che-3(am165)]	20°C																																																	none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	unknown strain [che-3(am165)]	20°C																																																	none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
70 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	unknown strain [che-3(am165)]	20°C																																																	none		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
80 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	unknown strain [che-3(am165)]	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
85 mM	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	unknown strain [che-3(am165)]	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR802 [osm-3(p802)]	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR802 [osm-3(p802)]	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR801 [che-3(p801)]	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	PR801 [che-3(p801)]	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	unknown strain [che-3(am165)]	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
30 mM (UV-treated ethosuximide)	whole life; start: L4	OP50, UV-inactivated	NGM agar	FUDR; ampicillin	unknown strain [che-3(am165)]	20°C																																																	down		n.d.	5 days after egg stage					Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.