5 µg/ml | whole life; start: A1 | OP50 | NGM agar | | HE250 [unc-52(e669su250)] | 25°C | up | | yes | A2; endpoint: number of paralyzed animals | | | | | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
10 µg/ml | whole life; start: A1 | OP50 | NGM agar | | HE250 [unc-52(e669su250)] | 25°C | up | | yes | A2; endpoint: number of paralyzed animals | | | | | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
15 µg/ml | whole life; start: A1 | OP50 | NGM agar | | HE250 [unc-52(e669su250)] | 25°C | up | | yes | A2; endpoint: number of paralyzed animals | | | | | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | HE250 [unc-52(e669su250)] | 25°C | up | | yes | A2; endpoint: number of paralyzed animals | | | | | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
5 µg/ml | whole life; start: A1 | OP50 | NGM agar | | CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]} | 25°C | up | | yes | A5; endpoint: number of paralyzed animals | | | | | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
10 µg/ml | whole life; start: A1 | OP50 | NGM agar | | CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]} | 25°C | up | | yes | A5; endpoint: number of paralyzed animals | | | | | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
15 µg/ml | whole life; start: A1 | OP50 | NGM agar | | CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]} | 25°C | up | | yes | A5; endpoint: number of paralyzed animals | | | | | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]} | 25°C | up | | yes | A5; endpoint: number of paralyzed animals | | | | | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | start: L4; stop: A1 | OP50 | NGM agar | | AM141 {rmIs133 [unc-54p::Q40::YFP]} | 25°C | up | | yes | A5; endpoint: body bends | | | | | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | N2 (wild type) | 20°C | | | | | up | | yes | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | none | | no | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | N2 (wild type) | 25°C | | | | | up | | yes | A1; Stressor: 35°C; endpoint: mean lifespan | down | | yes | A9; blue fluorescence | | | | | up | | yes | | none | | n.d. | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | CL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]} | 20°C | | | | | | | | | | | | | up | | yes | A1; pre-exposed to 35°C for 1 h; measured via fluorescence | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | CB4037 [glp-1(e2141)] | 25°C | | | | | down | | no | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | AA86 [daf-12(rh61rh411)] | 20°C | | | | | up | | yes | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | CF1038 [daf-16(mu86)] | 20°C | | | | | up | | yes | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | up | | yes | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | BX165 [nhr-80(tm1011)] | 20°C | | | | | up | | yes | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | PS3551 [hsf-1(sy441)] | 20°C | | | | | up | | yes | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | BA17 [fem-1(hc17)] | 25°C | | | | | none | | no | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | CB3844 [fem-3(e2006)] | 25°C | | | | | none | | no | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | none | | no | | no | | n.d. | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | CB3844 [fem-3(e2006)]; mated | 25°C | | | | | up | | yes | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | BA24 [fer-1(hc24)] | 25°C | | | | | up | | yes | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | BA6 [fer-6(hc6)] | 25°C | | | | | up | | yes | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |
100 µg/ml | whole life; start: A1 | OP50 | NGM agar | | BA671 [spe-9(hc88)] | 25°C | | | | | up | | yes | A1; Stressor: 35°C; endpoint: mean lifespan | | | | | | | | | | | | | | | | | | | | | Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769. | no |