Compound ID 171   (prev - next)

Name: FUdR (5-fluoro 2-deoxyuridine) (3363) (edit)

26 entries:
TreatmentFUdR (5-fluoro 2-deoxyuridine)physical functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)3363ChEMBLlocomotion on solid mediaheat stress resistanceautofluorescence (age pigment / lipofuscin)activity / quantity / expression of HSPsmean lifespanmaximum lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
5 µg/mlwhole life; start: A1OP50NGM agarHE250 [unc-52(e669su250)]25°CupyesA2; endpoint: number of paralyzed animalsAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
10 µg/mlwhole life; start: A1OP50NGM agarHE250 [unc-52(e669su250)]25°CupyesA2; endpoint: number of paralyzed animalsAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
15 µg/mlwhole life; start: A1OP50NGM agarHE250 [unc-52(e669su250)]25°CupyesA2; endpoint: number of paralyzed animalsAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarHE250 [unc-52(e669su250)]25°CupyesA2; endpoint: number of paralyzed animalsAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
5 µg/mlwhole life; start: A1OP50NGM agarCL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}25°CupyesA5; endpoint: number of paralyzed animalsAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
10 µg/mlwhole life; start: A1OP50NGM agarCL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}25°CupyesA5; endpoint: number of paralyzed animalsAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
15 µg/mlwhole life; start: A1OP50NGM agarCL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}25°CupyesA5; endpoint: number of paralyzed animalsAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarCL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}25°CupyesA5; endpoint: number of paralyzed animalsAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlstart: L4; stop: A1OP50NGM agarAM141 {rmIs133 [unc-54p::Q40::YFP]}25°CupyesA5; endpoint: body bendsAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarN2 (wild type)20°CupyesA1; Stressor: 35°C; endpoint: mean lifespannonenoAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarN2 (wild type)25°CupyesA1; Stressor: 35°C; endpoint: mean lifespandownyesA9; blue fluorescenceupyesnonen.d.Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarCL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}20°CupyesA1; pre-exposed to 35°C for 1 h; measured via fluorescenceAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarCB4037 [glp-1(e2141)]25°CdownnoA1; Stressor: 35°C; endpoint: mean lifespanAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarAA86 [daf-12(rh61rh411)]20°CupyesA1; Stressor: 35°C; endpoint: mean lifespanAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarCF1038 [daf-16(mu86)]20°CupyesA1; Stressor: 35°C; endpoint: mean lifespanupyesAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarBX165 [nhr-80(tm1011)]20°CupyesA1; Stressor: 35°C; endpoint: mean lifespanAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarPS3551 [hsf-1(sy441)]20°CupyesA1; Stressor: 35°C; endpoint: mean lifespanAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarBA17 [fem-1(hc17)]25°CnonenoA1; Stressor: 35°C; endpoint: mean lifespanAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarCB3844 [fem-3(e2006)]25°CnonenoA1; Stressor: 35°C; endpoint: mean lifespannonenonon.d.Angeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarCB3844 [fem-3(e2006)]; mated25°CupyesA1; Stressor: 35°C; endpoint: mean lifespanAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarBA24 [fer-1(hc24)]25°CupyesA1; Stressor: 35°C; endpoint: mean lifespanAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarBA6 [fer-6(hc6)]25°CupyesA1; Stressor: 35°C; endpoint: mean lifespanAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no
100 µg/mlwhole life; start: A1OP50NGM agarBA671 [spe-9(hc88)]25°CupyesA1; Stressor: 35°C; endpoint: mean lifespanAngeli S, Klang I, Sivapatham R, Mark K, Zucker D, Bhaumik D, Lithgow GJ, Andersen JK (2013) A DNA synthesis inhibitor is protective against proteotoxic stressors via modulation of fertility pathways in Caenorhabditis elegans. Aging (Albany NY) 5, 759-769.no