Compound ID 176 (prev - next)

Name: Gallic acid (370) (edit)

11 entries:

Treatment	Gallic acid						physical function								reproductive function												physiological function								healthspan biomarkers								lifespan								Reference	blinded
CID (PubChem)	370	ChEMBL	CHEMBL288114				pharyngeal pumping				body length / growth rate				number of offspring				quantity of early reproduction				onset of egg laying				heat stress resistance				oxidative stress resistance				triglyceride / fat / lipid content				antioxidative capacity				median lifespan				mean lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
100 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																					up		no	A6; Stressor: 35°C for 8 h; endpoint: survival	none		no	A6; Stressor: 0.8 mM H2O2 for 8 h; endpoint: survival													up		yes		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
200 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																					up		no	A6; Stressor: 35°C for 8 h; endpoint: survival	none		no	A6; Stressor: 0.8 mM H2O2 for 8 h; endpoint: survival													up		yes		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
300 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C	up		yes	A9; non-significant increase at A3 and A6	up		yes	A6	none		no		down		yes		delayed		yes		up		no	A6; Stressor: 35°C for 8 h; endpoint: survival	none		no	A6; Stressor: 0.8 mM H2O2 for 8 h; endpoint: survival	down		no	A1	none		no	A1					up		yes		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
400 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																					up		yes	A6; Stressor: 35°C for 8 h; endpoint: survival	none		no	A6; Stressor: 0.8 mM H2O2 for 8 h; endpoint: survival													up		yes		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
800 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																					up		yes	A6; Stressor: 35°C for 8 h; endpoint: survival	none		no	A6; Stressor: 0.8 mM H2O2 for 8 h; endpoint: survival													up		no		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
300 µM	whole life; start: parental generation	OP50	NGM agar		TK22 [mev-1(kn1)]	20°C																																									up		yes		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
300 µM	whole life; start: parental generation	OP50	NGM agar		DA465 [eat-2(ad465)]	20°C																																					up	11.00	n.d.		up	7.00	no		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
300 µM	whole life; start: parental generation	OP50 until A6; from A6: OP50, heat-inactivated	NGM agar		N2 (wild type)	20°C																																									none		no		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no