| Treatment | Ginkgolide B | lifespan | Transcriptome | Proteome | Metabolome | Target | Reference | blinded | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CID (PubChem) | 65243 | ChEMBL | median lifespan | maximum lifespan | ||||||||||||||||
| Concentration | Exposure time | Food | Growth medium | Special additives | C. elegans strain | Temperature | Change compared to control | Percentual change compared to control | p < 0.05 | notes | Change compared to control | Percentual change compared to control | p < 0.05 | notes | ||||||
| 50 µg/ml | whole life; start: A1 | OP50 | NGM agar | N2 (wild type) | 22 °C | up | 8.33 | yes | significance was determined for mean lifespan (log rank test) | up | 5.56 | Wu Z, Smith JV, Paramasivam V, Butko P, Khan I, Cypser JR, Luo Y (2002) Ginkgo biloba extract EGb 761 increases stress resistance and extends life span of Caenorhabditis elegans. Cell Mol Biol (Noisy-le-grand) 48, 725-731. | ||||||||