Compound ID 183   (prev - next)

Name: Glochidion zeylanicum, methanol extract (edit)

24 entries:
TreatmentGlochidion zeylanicum, methanol extractphysical functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)ChEMBLpharyngeal pumpingoxidative stress resistanceROS levelactivity / quantity / expression of HSPstranslocation of DAF-16 to nucleusactivity / quantity / expression of SODstranslocation of SKN-1 to nucleusautofluorescence (age pigment / lipofuscin)activity / quantity / expression of GSTsmean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperaturechange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)notes
1 µg/mlwhole life; start: n.d.OP50NGM agarN2 (wild type)20°CupyesA5, A8, A10, A12upyesstressor: 80 μM juglone; endpoint: survival; 48h of compound treatmentdown-63.54yesmeasured via H2DCF-DA; 48h of compound treatmentup7.98yesDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
2.5 µg/mlwhole life; start: n.d.OP50NGM agarN2 (wild type)20°CupyesA5, A8, A10, A12; not significant at A12upyesstressor: 80 μM juglone; endpoint: survival; 48h of compound treatmentdown-42.47yesmeasured via H2DCF-DA; 48h of compound treatmentnonenoDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
5 µg/mlwhole life; start: n.d.OP50NGM agarN2 (wild type)20°CupyesA5, A8, A10, A12; not significant at A12upnostressor: 80 μM juglone; endpoint: survival; 48h of compound treatmentupnomeasured via H2DCF-DA; 48h of compound treatmentup8.75yesDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
1 µg/mlwhole life; start: n.d.OP50NGM agarTJ375 {gpIs1 [hsp-16.2p::GFP]}20°Cdown-67.09yespre-exposed to juglone; 48h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
2.5 µg/mlwhole life; start: n.d.OP50NGM agarTJ375 {gpIs1 [hsp-16.2p::GFP]}20°Cdown-32.13yespre-exposed to juglone; 48h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
5 µg/mlwhole life; start: n.d.OP50NGM agarTJ375 {gpIs1 [hsp-16.2p::GFP]}20°Cdown-36.7yespre-exposed to juglone; 48h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
1 µg/mlwhole life; start: n.d.OP50NGM agarCF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}20°Cup18.02yespre-exposed to juglone; 48h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
2.5 µg/mlwhole life; start: n.d.OP50NGM agarCF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}20°Cup16.2yespre-exposed to juglone; 48h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
5 µg/mlwhole life; start: n.d.OP50NGM agarCF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}20°Cnonenopre-exposed to juglone; 48h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
1 µg/mlwhole life; start: n.d.OP50NGM agarCL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}20°Cup29.8yespre-exposed to juglone; 48h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
2.5 µg/mlwhole life; start: n.d.OP50NGM agarCL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}20°Cup57.4yespre-exposed to juglone; 48h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
5 µg/mlwhole life; start: n.d.OP50NGM agarCL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}20°Cup54.2yespre-exposed to juglone; 48h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
1 µg/mlwhole life; start: n.d.OP50NGM agarTJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}20°Cupyes72h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
2.5 µg/mlwhole life; start: n.d.OP50NGM agarTJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}20°Cupyes72h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
5 µg/mlwhole life; start: n.d.OP50NGM agarTJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}20°Cupyes72h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
1 µg/mlwhole life; start: n.d.OP50NGM agarEU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]]20°Cupyes72h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
2.5 µg/mlwhole life; start: n.d.OP50NGM agarEU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]]20°Cupyes72h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
5 µg/mlwhole life; start: n.d.OP50NGM agarEU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]]20°Cnoneno72h of compound treatmentDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
1 µg/mlwhole life; start: n.d.OP50NGM agarBA17 [fem-1(hc17)]25°Cdown-7.54yesA16; blue fluorescenceDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
2.5 µg/mlwhole life; start: n.d.OP50NGM agarBA17 [fem-1(hc17)]25°Cdown-12.12yesA16; blue fluorescenceDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no
5 µg/mlwhole life; start: n.d.OP50NGM agarBA17 [fem-1(hc17)]25°Cdown-8.17yesA16; blue fluorescenceDuangjan C, Rangsinth P, Gu X, Zhang S, Wink M, Tencomnao T (2019) Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways. Phytomedicine 64, 153061. no