Compound ID 196 (prev - next)

Name: Holothuria leucospilota, aqueous extract (edit)

11 entries:

Treatment	Holothuria leucospilota, aqueous extract						lifespan								Reference	blinded
CID (PubChem)		ChEMBL					mean lifespan				maximum lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	change compared to control	percentage change compared to control	significant (p < 0.05)	notes	change compared to control	percentage change compared to control	significant (p < 0.05)	notes
10 µg/ml	whole life; start: L4	OP50	NGM agar	FUdR	N2 (wild type)	25°C	down	-2.86	yes		none		n.d.		Kitisin T, Suphamungmee W, Meemon K (2019) Saponin-rich extracts from Holothuria leucospilota mediate lifespan extension and stress resistance in Caenorhabditis elegans via daf-16. J Food Biochem 43, e13075.	no
100 µg/ml	whole life; start: L4	OP50	NGM agar	FUdR	N2 (wild type)	25°C	down	-0.72	no		none		n.d.		Kitisin T, Suphamungmee W, Meemon K (2019) Saponin-rich extracts from Holothuria leucospilota mediate lifespan extension and stress resistance in Caenorhabditis elegans via daf-16. J Food Biochem 43, e13075.	no
500 µg/ml	whole life; start: L4	OP50	NGM agar	FUdR	N2 (wild type)	25°C	down	-2.23	no		none		n.d.		Kitisin T, Suphamungmee W, Meemon K (2019) Saponin-rich extracts from Holothuria leucospilota mediate lifespan extension and stress resistance in Caenorhabditis elegans via daf-16. J Food Biochem 43, e13075.	no
1000 µg/ml	whole life; start: L4	OP50	NGM agar	FUdR	N2 (wild type)	25°C	up	2.23	yes		up	6.7	n.d.		Kitisin T, Suphamungmee W, Meemon K (2019) Saponin-rich extracts from Holothuria leucospilota mediate lifespan extension and stress resistance in Caenorhabditis elegans via daf-16. J Food Biochem 43, e13075.	no
10 µg/ml	whole life; start: L1	OP50	NGM agar	FUdR	N2 (wild type)	25°C	up	1.78	no		up	5.9	n.d.		Kitisin T, Suphamungmee W, Meemon K (2019) Saponin-rich extracts from Holothuria leucospilota mediate lifespan extension and stress resistance in Caenorhabditis elegans via daf-16. J Food Biochem 43, e13075.	no
100 µg/ml	whole life; start: L1	OP50	NGM agar	FUdR	N2 (wild type)	25°C	up	2.15	no		up	5.9	n.d.		Kitisin T, Suphamungmee W, Meemon K (2019) Saponin-rich extracts from Holothuria leucospilota mediate lifespan extension and stress resistance in Caenorhabditis elegans via daf-16. J Food Biochem 43, e13075.	no
500 µg/ml	whole life; start: L1	OP50	NGM agar	FUdR	N2 (wild type)	25°C	none		no		none		n.d.		Kitisin T, Suphamungmee W, Meemon K (2019) Saponin-rich extracts from Holothuria leucospilota mediate lifespan extension and stress resistance in Caenorhabditis elegans via daf-16. J Food Biochem 43, e13075.	no
1000 µg/ml	whole life; start: L1	OP50	NGM agar	FUdR	N2 (wild type)	25°C	none		no		none		n.d.		Kitisin T, Suphamungmee W, Meemon K (2019) Saponin-rich extracts from Holothuria leucospilota mediate lifespan extension and stress resistance in Caenorhabditis elegans via daf-16. J Food Biochem 43, e13075.	no