Compound ID 222   (prev - next)

Name: Liangyi Gao (TCM) (edit)

6 entries:
TreatmentLiangyi Gao (TCM)physical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)ChEMBLpharyngeal pumpinglocomotion on solid mediabody length / growth ratenumber of offspringquantity of late reproductionoxidative stress resistanceheat stress resistancetranslocation of DAF-16 to nucleusactivity / quantity / expression of SODsautofluorescence (age pigment / lipofuscin)mean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperaturechange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)notes
1 mg/mlwhole life; start: n.d.OP50NGM agarN2 (wild type)20°Cupn.d.A4upyesA7upyesA4upyesupn.d.upyesA4; stressor: H2O2; endpoint: mean survivalupyesA4; stressor: 37°C; endpoint: mean survivalupyesdown-34.2yesA10; green fluorescenceup23.8yesupregulation of daf-16, sod-3, sir-2.1Zeng L, Sun C, Pei Z, Yun T, Fan S, Long S, Wu T, Chen Z, Yang Z, Xu F (2019) Liangyi Gao extends lifespan and exerts an antiaging effect in Caenorhabditis elegans by modulating DAF-16/FOXO. Biogerontology 20, 665-676. no
1 mg/mlwhole life; start: n.d.OP50NGM agarCF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}20°CupyesA3, pre-exposed to heat stressZeng L, Sun C, Pei Z, Yun T, Fan S, Long S, Wu T, Chen Z, Yang Z, Xu F (2019) Liangyi Gao extends lifespan and exerts an antiaging effect in Caenorhabditis elegans by modulating DAF-16/FOXO. Biogerontology 20, 665-676. no
1 mg/mlwhole life; start: n.d.OP50NGM agarTJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}20°Cupn.d.A3Zeng L, Sun C, Pei Z, Yun T, Fan S, Long S, Wu T, Chen Z, Yang Z, Xu F (2019) Liangyi Gao extends lifespan and exerts an antiaging effect in Caenorhabditis elegans by modulating DAF-16/FOXO. Biogerontology 20, 665-676. no