Compound ID 226 (prev - next)

Name: Liuwei dihuang wan (TCM formula; water extract) (edit)

8 entries:

Treatment	Liuwei dihuang wan (TCM formula; water extract)						physical function				healthspan biomarkers				Reference
CID (PubChem)							locomotion on solid media				activity / quantity / expression of HSPs
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
0.1 mg/ml	whole life; start: egg stage	OP50	NGM agar	Gentamycin	CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}	16°C	none		no	L3; temperature shift to 23°C prior analysing beta-amyloid induced paralysis					Sangha, J. S., Sun, X., Wally, O. S., Zhang, K., Ji, X., Wang, Z., ... & Zhang, J. (2012). Liuwei Dihuang (LWDH), a traditional Chinese medicinal formula, protects against β-amyloid toxicity in transgenic Caenorhabditis elegans. PLoS One, 7(8).
0.5 mg/ml	whole life; start: egg stage	OP50	NGM agar	Gentamycin	CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}	16°C	none		no	L3; temperature shift to 23°C prior analysing beta-amyloid induced paralysis					Sangha, J. S., Sun, X., Wally, O. S., Zhang, K., Ji, X., Wang, Z., ... & Zhang, J. (2012). Liuwei Dihuang (LWDH), a traditional Chinese medicinal formula, protects against β-amyloid toxicity in transgenic Caenorhabditis elegans. PLoS One, 7(8).
1 mg/ml	whole life; start: egg stage	OP50	NGM agar	Gentamycin	CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}	16°C	up	8	yes	L3; temperature shift to 23°C prior analysing beta-amyloid induced paralysis					Sangha, J. S., Sun, X., Wally, O. S., Zhang, K., Ji, X., Wang, Z., ... & Zhang, J. (2012). Liuwei Dihuang (LWDH), a traditional Chinese medicinal formula, protects against β-amyloid toxicity in transgenic Caenorhabditis elegans. PLoS One, 7(8).
2 mg/ml	whole life; start: egg stage	OP50	NGM agar	Gentamycin	CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}	16°C	up	16	yes	L3; temperature shift to 23°C prior analysing beta-amyloid induced paralysis					Sangha, J. S., Sun, X., Wally, O. S., Zhang, K., Ji, X., Wang, Z., ... & Zhang, J. (2012). Liuwei Dihuang (LWDH), a traditional Chinese medicinal formula, protects against β-amyloid toxicity in transgenic Caenorhabditis elegans. PLoS One, 7(8).
0.5 mg/ml	whole life; start: egg stage	OP50	NGM agar	Gentamycin	TJ375 {gpIs1 [hsp-16.2p::GFP]}	20°C					up		yes	A1; no significant changes at A2 & A3; exposure to 35°C for 2h at L4	Sangha, J. S., Sun, X., Wally, O. S., Zhang, K., Ji, X., Wang, Z., ... & Zhang, J. (2012). Liuwei Dihuang (LWDH), a traditional Chinese medicinal formula, protects against β-amyloid toxicity in transgenic Caenorhabditis elegans. PLoS One, 7(8).