Compound ID 233   (prev - next)

Name: 3ß-Methoxy-pregnenolone (MAP4343) (134159554) (edit)

46 entries:
Treatment3ß-Methoxy-pregnenolone (MAP4343)cognitive functionhealthspan biomarkersTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)134159554ChEMBLmechanical sensory / touch responseaxonal HTT (exon-1 huntingtin)-aggregatesaxonal dystrophy
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
100 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID1 {igIs1 [mec-3p::htt57-128Q::CFP; lin-15(+); mec-7p::YFP]}20 °CnonenodownyesFarina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}20 °Cup21,3yesA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}20 °CupyesA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}20 °CupnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}20 °CdownnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinunnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinunnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinunnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinunnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinunnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinunnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinunnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinDR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupyesA1nonenoFarina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinDR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinDR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinDR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinDR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinDR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinDR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinEW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupyesA1nonenoFarina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinEW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinEW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinEW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinEW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinEW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinEW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}20 °CupnoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinRB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinRB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinRB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinRB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinRB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinRB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µMwhole life; start: L1OP50-1liquid S-mediumstreptomycinRB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}20 °CnonenoA1Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.