Compound ID 248   (prev - next)

Name: N-Nitrosodimethylamine (6124) (edit)

9 entries:
TreatmentN-Nitrosodimethylaminephysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)6124ChEMBLpharyngeal pumpingbody length / growth ratenumber of offspringvertex (progeny per day)heat stress resistanceMDA levelmedian lifespanmean lifespanmaximum lifespanminimum lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
50 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CnonenoA6upyesA6nonenononenononenoA1; stressor: 35°C; endpoint: survivaldownnoA1up1.76n.d.up5.44yesup3.39n.d.up7.13n.d.down-regulation of cep-1, egl-1, rad-51, hsp-16.1, hsp-70, gst-4, gst-38, gstk-1, and sod-1Baberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no
100 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CupnoA6upnoA6down-1.02n.d.up1.55yesup0.62n.d.up7.49n.d.Baberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no
0.1 mMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CnonenoA6nonenononenononenoA1; stressor: 35°C; endpoint: survivaldown-regulation of egl-1, rad-51, hsp-16.1, and gst-38Baberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no
0.5 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CupnoA6nonenononenononenoA1; stressor: 35°C; endpoint: survivalBaberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no
2 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CupnoA6nonenononenononenoA1; stressor: 35°C; endpoint: survivalBaberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no
10 µMwhole life; start: parental generationOP50NGM agarN2 (wild type)20°CupyesA6nonenononenononenoA1; stressor: 35°C; endpoint: survivalBaberschke N, Steinberg CE, Saul N (2015) Low concentrations of dibromoacetic acid and N-nitrosodimethylamine induce several stimulatory effects in the invertebrate model Caenorhabditis elegans. Chemosphere 124, 122-128. no