| Treatment | Nymphaea hybrid (total flavones) | physiological function | lifespan | Transcriptome | Proteome | Metabolome | Target | Reference | blinded | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CID (PubChem) | ChEMBL | heat stress resistance | oxidative stress resistance | mean lifespan | ||||||||||||||||||||
| Concentration | Exposure time | Food | Growth medium | Special additives | C. elegans strain | Temperature | Change compared to control | Percentual change compared to control | p < 0.05 | notes | Change compared to control | Percentual change compared to control | p < 0.05 | notes | Change compared to control | Percentual change compared to control | p < 0.05 | notes | ||||||
| 100 µg/ml | whole life; start: L4 | OP50 | NGM agar | N2 (wild type) | 20°C | up | yes | A2; stressor: 35°C for 16h; endpoint: survival | up | yes | A2; stressor: 0.1 mg/ml of paraquat for 4d; endpoint: survival | up | yes | Zhuang, Z., Lv, T., Li, M., Zhang, Y., Xue, T., Yang, L., ... & Zhang, W. (2014). The lifespan-extending effects of Nymphaea hybrid root extract in the nematode Caenorhabditis elegans. Plant foods for human nutrition, 69(4), 304-309. | ||||||||||