Compound ID 264   (prev - next)

Name: Oleic acid (445639) (edit)

5 entries:
TreatmentOleic acidphysiological functionhealthspan biomarkersTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)445639ChEMBLoxidative stress resistanceROS leveltranslocation of DAF-16 to nucleus
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
0.066 mg/mlwhole life; start: L1OP50liquid S-mediumN2 (wild type)20°Cup36.00yesA1; stressor: 250 µM juglone for 2.5 h; endpoint: survivalnonenoA1; measured via H2DCF-DADAF-16Wei CC, Yen PL, Chang ST, Cheng PL, Lo YC, Liao VH (2016) Antioxidative Activities of Both Oleic Acid and Camellia tenuifolia Seed Oil Are Regulated by the Transcription Factor DAF-16/FOXO in Caenorhabditis elegans. PLoS One 11, e0157195.
0.066 mg/mlwhole life; start: L1OP50liquid S-mediumTJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}20°Cup108.33n.d.A1; pre-exposure to 50 μM juglonefor 5 minWei CC, Yen PL, Chang ST, Cheng PL, Lo YC, Liao VH (2016) Antioxidative Activities of Both Oleic Acid and Camellia tenuifolia Seed Oil Are Regulated by the Transcription Factor DAF-16/FOXO in Caenorhabditis elegans. PLoS One 11, e0157195.