Compound ID 274   (prev - next)

Name: paroxetine (43815) (edit)

8 entries:
Treatmentparoxetinecognitive functionhealthspan biomarkersTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)43815ChEMBLmechanical sensory / touch responsequantity of β-Amyloid
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
10 nMwhole life; start: egg stageOP50NGM agarCL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}20°Cnoneparalysis assay with daily measurements of Alzheimer disease modelKeowkase R, Aboukhatwa M, Luo Y (2010) Fluoxetine protects against amyloid-beta toxicity, in part via daf-16 mediated cell signaling pathway, in Caenorhabditis elegans. Neuropharmacology 59, 358-365.
100 nMwhole life; start: egg stageOP50NGM agarCL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}20°Cupyesparalysis assay with daily measurements of Alzheimer disease modeldownn.d.A1Keowkase R, Aboukhatwa M, Luo Y (2010) Fluoxetine protects against amyloid-beta toxicity, in part via daf-16 mediated cell signaling pathway, in Caenorhabditis elegans. Neuropharmacology 59, 358-365.
1 µMwhole life; start: egg stageOP50NGM agarCL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}20°Cnoneparalysis assay with daily measurements of Alzheimer disease modelKeowkase R, Aboukhatwa M, Luo Y (2010) Fluoxetine protects against amyloid-beta toxicity, in part via daf-16 mediated cell signaling pathway, in Caenorhabditis elegans. Neuropharmacology 59, 358-365.
10 µMwhole life; start: egg stageOP50NGM agarCL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}20°Cnoneparalysis assay with daily measurements of Alzheimer disease modelKeowkase R, Aboukhatwa M, Luo Y (2010) Fluoxetine protects against amyloid-beta toxicity, in part via daf-16 mediated cell signaling pathway, in Caenorhabditis elegans. Neuropharmacology 59, 358-365.
100 µMwhole life; start: egg stageOP50NGM agarCL2006 {dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + pRF4]}20°Cnoneparalysis assay with daily measurements of Alzheimer disease modelKeowkase R, Aboukhatwa M, Luo Y (2010) Fluoxetine protects against amyloid-beta toxicity, in part via daf-16 mediated cell signaling pathway, in Caenorhabditis elegans. Neuropharmacology 59, 358-365.