Compound ID 279   (prev - next)

Name: Platycladus orientalis extract (n-butanol extract from seed) (edit)

8 entries:
TreatmentPlatycladus orientalis extract (n-butanol extract from seed)physiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)ChEMBLheat stress resistanceoxidative stress resistanceautofluorescence (age pigment / lipofuscin)ROS levelactivity / quantity / expression of HSPsactivity / quantity / expression of GSTsmean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
20 µg/mlwhole life; start: L4OP50NGM agarN2 (wild type)20°Cup1.67noLiu H, Liang F, Su W, Wang N, Lv M, Li P, Pei Z, Zhang Y, Xie XQ, Wang L, Wang Y (2013) Lifespan extension by n-butanol extract from seed of Platycladus orientalis in Caenorhabditis elegans. J Ethnopharmacol 147, 366-372. yes
100 µg/mlwhole life; start: L4OP50NGM agarN2 (wild type)20°Cup9.91yesLiu H, Liang F, Su W, Wang N, Lv M, Li P, Pei Z, Zhang Y, Xie XQ, Wang L, Wang Y (2013) Lifespan extension by n-butanol extract from seed of Platycladus orientalis in Caenorhabditis elegans. J Ethnopharmacol 147, 366-372. yes
500 µg/mlwhole life; start: L4OP50NGM agarN2 (wild type)20°Cup17.70yesA3; Stressor: 35°C for 1 h; endpoint: mean lifespanup62.00yesA2; Stressor: 500 µM juglone for 5 hdown-41.7yesA10down-34.3yesA2; measured with DCF-DAup24.54yesLiu H, Liang F, Su W, Wang N, Lv M, Li P, Pei Z, Zhang Y, Xie XQ, Wang L, Wang Y (2013) Lifespan extension by n-butanol extract from seed of Platycladus orientalis in Caenorhabditis elegans. J Ethnopharmacol 147, 366-372. yes
500 µg/mlwhole life; start: L1OP50NGM agarCL2070 {dvIs70 [hsp-16.2p::GFP + rol-6(su1006)]}20°Cup122yesA4; 1 day before measurement: heat shock at 25°C for 30 min and 35°C for 1 h)Liu H, Liang F, Su W, Wang N, Lv M, Li P, Pei Z, Zhang Y, Xie XQ, Wang L, Wang Y (2013) Lifespan extension by n-butanol extract from seed of Platycladus orientalis in Caenorhabditis elegans. J Ethnopharmacol 147, 366-372. yes
500 µg/mlwhole life; start: L1OP50NGM agarCL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}20°Cup129.00yesA1; measured via fluorescenceLiu H, Liang F, Su W, Wang N, Lv M, Li P, Pei Z, Zhang Y, Xie XQ, Wang L, Wang Y (2013) Lifespan extension by n-butanol extract from seed of Platycladus orientalis in Caenorhabditis elegans. J Ethnopharmacol 147, 366-372. yes