Compound ID 293   (prev - next)

Name: Rechtsregulat® (edit)

7 entries:
TreatmentRechtsregulat®physiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)ChEMBLheat stress resistanceATP levellactate levelpyruvate levelmitochondrial content/qualitymitochondrial membrane potentialmedian lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperaturechange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)notes
5%whole life; start: A1OP50NGM agarN2 (wild type)20°CDilberger B, Passon M, Asseburg H, Silaidos CV, Schmitt F, Schmiedl T, Schieber A, Eckert GP (2019) Polyphenols and Metabolites Enhance Survival in Rodents and Nematodes-Impact of Mitochondria. Nutrients 11, 1886. no
10%whole life; start: A1OP50NGM agarN2 (wild type)20°Cup10yesA3; upregulation of daf-16, skn-1Dilberger B, Passon M, Asseburg H, Silaidos CV, Schmitt F, Schmiedl T, Schieber A, Eckert GP (2019) Polyphenols and Metabolites Enhance Survival in Rodents and Nematodes-Impact of Mitochondria. Nutrients 11, 1886. no
5%whole life; start: A1OP50liquid NGMN2 (wild type)20°CnonenoA3, stressor: 37°C; endpoint: median lifespanDilberger B, Passon M, Asseburg H, Silaidos CV, Schmitt F, Schmiedl T, Schieber A, Eckert GP (2019) Polyphenols and Metabolites Enhance Survival in Rodents and Nematodes-Impact of Mitochondria. Nutrients 11, 1886. no
10%whole life; start: A1OP50liquid NGMN2 (wild type)20°Cup9.5A3, stressor: 37°C; endpoint: median lifespandownnoA3up143yesA3upnoA3upyesA3; determined by the activities of mitochondrial respiratory systemdownnoA3; determined with the fluorescent dye Rhodamine 123Dilberger B, Passon M, Asseburg H, Silaidos CV, Schmitt F, Schmiedl T, Schieber A, Eckert GP (2019) Polyphenols and Metabolites Enhance Survival in Rodents and Nematodes-Impact of Mitochondria. Nutrients 11, 1886. no