Compound ID 3   (prev - next)

Name: 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG) from Curcuma longa L (65238) (edit)

5 entries:
Treatment1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG) from Curcuma longa Lphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)65238ChEMBLheat stress resistanceoxidative stress resistanceROS levelactivity / quantity / expression of SODsmean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
50 µMwhole life; start: egg stageOP50NGM agarN2 (wild type)20°CupyesA4; Stressor: 36°C for 16 h; endpoint: mean lifespanupyesA7; Stressor: 60 mM paraquat; endpoint: mean lifespandownnoA4; pre-exposed to 60 mM paraquat for 3 h; measured via H2-DCF-DAupnoA5; SOD-activity determined with the aid of formazanupyesAhn D, Cha DS, Lee EB, Kim BJ, Lee SY, Jeon H, Ahn MS, Lim HW, Lee HY, Kim DK (2013) The Longevity Properties of 1,2,3,4,6-Penta-O-Galloyl-β-D-Glucose from Curcuma longa in Caenorhabditis elegans. Biomol Ther (Seoul) 21, 442-446.
100 µMwhole life; start: egg stageOP50NGM agarN2 (wild type)20°Cup23.00yesA4; Stressor: 36°C for 16 h; endpoint: mean lifespanupyesA7; Stressor: 60 mM paraquat; endpoint: mean lifespandownyesA4; pre-exposed to 60 mM paraquat for 3 h; measured via H2-DCF-DAupyesA5; SOD-activity determined with the aid of formazanup15.70yesAhn D, Cha DS, Lee EB, Kim BJ, Lee SY, Jeon H, Ahn MS, Lim HW, Lee HY, Kim DK (2013) The Longevity Properties of 1,2,3,4,6-Penta-O-Galloyl-β-D-Glucose from Curcuma longa in Caenorhabditis elegans. Biomol Ther (Seoul) 21, 442-446.