Treatment | S-n-propylcysteine | healthspan biomarkers | Transcriptome | Proteome | Metabolome | Target | Reference | blinded | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CID (PubChem) | 101975 | ChEMBL | activity / quantity / expression of GSTs | |||||||||||||
Concentration | Exposure time | Food | Growth medium | Special additives | C. elegans strain | Temperature | Change compared to control | Percentual change compared to control | p < 0.05 | notes | ||||||
10 µM | whole life; start: A1 | OP50, UV-inactivated | liquid S-medium | amphotericin B | CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]} | 20°C | up | 30.00 | no | A2; expression of gst-4; measured via fluorescence | Ogawa T, Kodera Y, Hirata D, Blackwell TK, Mizunuma M (2016) Natural thioallyl compounds increase oxidative stress resistance and lifespan in Caenorhabditis elegans by modulating SKN-1/Nrf. Sci Rep 6, 21611. |