Compound ID 328   (prev - next)

Name: Succinimide (11439) (edit)

10 entries:
TreatmentSuccinimidelifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)11439ChEMBLmean lifespansurvival at a given time pointmaximum lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
2 mg/mlwhole life; start: parental generationOP50NGM agarN2 (wild type)20°Cdown-4.00noup1.00noEvason K, Huang C, Yamben I, Covey DF, Kornfeld K (2005) Anticonvulsant medications extend worm life-span. Science. 307, 258-262.
5 mM (UV-treated succinimide)whole life; start: L4OP50, UV-inactivatedNGM agarFUDR; ampicillinN2 (wild type)20°CnoneA7Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mM (UV-treated succinimide)whole life; start: L4OP50, UV-inactivatedNGM agarFUDR; ampicillinN2 (wild type)20°CnoneA7Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
50 mM (UV-treated succinimide)whole life; start: L4OP50, UV-inactivatedNGM agarFUDR; ampicillinN2 (wild type)20°CnoneA7Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
5 mMwhole life; start: L4OP50, UV-inactivatedNGM agarFUDR; ampicillinN2 (wild type)20°CnoneA7Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
10 mMwhole life; start: L4OP50, UV-inactivatedNGM agarFUDR; ampicillinN2 (wild type)20°CnoneA7Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.
50 mMwhole life; start: L4OP50, UV-inactivatedNGM agarFUDR; ampicillinN2 (wild type)20°CnoneA7Choi H, Schneider H, Klum S, Chandler-Brown D, Kaeberlein M, Shamieh L (2013) UV-photoconversion of ethosuximide from a longevity-promoting compound to a potent toxin. PLoS One 8, e82543.