Compound ID 332 (prev - next)

Name: Tannic acid (16129878) (edit)

38 entries:

Treatment	Tannic acid						physical function								reproductive function																physiological function								healthspan biomarkers								lifespan								Reference	blinded
CID (PubChem)	16129878	ChEMBL	506247				pharyngeal pumping				body length / growth rate				number of offspring				vertex (progeny per day)				onset of egg laying				quantity of early reproduction				heat stress resistance				oxidative stress resistance				triglyceride / fat / lipid content				antioxidative capacity				median lifespan				mean lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
25 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																																									up	7.95	n.d.		up	10.26	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
50 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																																									up	17.47	n.d.		up	16.17	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C	none		no	A3, A6, and A9	down		yes	A1, A2, A3, A4, and A6	none		no		none		no										up		yes	A6; stressor: 35°C for 8 h; endpoint: survival	up		yes	A6; stressor: 0.8 mM H2O2 for 8 h; endpoint: survival									up	17.64	n.d.		up	17.61	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
200 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																									up		yes	A6; stressor: 35°C for 8 h; endpoint: survival	up		no	A6; stressor: 0.8 mM H2O2 for 8 h; endpoint: survival									up	10.66	n.d.		up	8.35	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
300 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																									up		yes	A6; stressor: 35°C for 8 h; endpoint: survival	none		no	A6; stressor: 0.8 mM H2O2 for 8 h; endpoint: survival									up	2.16	n.d.		down	-0.92	no		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
400 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																																									down	-9.41	n.d.		down	-10.51	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	15°C																																									up	17.58	n.d.		up	20.38	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	23°C																																									up	68.62	n.d.		up	47.20	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	start: parental generation; stop: A6	OP50	NGM agar		N2 (wild type)	20°C																																									up	10.27	n.d.		up	7.93	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50 until A6; from A6: OP50, heat-inactivated	NGM agar		N2 (wild type)	20°C																																									up	17.45	n.d.		up	19.06	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	start: parental generation; stop: A6	OP50 until A6; from A6: OP50, heat-inactivated	NGM agar		N2 (wild type)	20°C																																									up	3.61	n.d.		up	6.57	no		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		TJ1052 [age-1(hx546)]	20°C																																									up	47.88	n.d.		up	35.01	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		VC204 [akt-2(ok393)]	20°C																																									up	18.44	n.d.		up	13.33	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		DR20 [daf-12(m20)]	20°C																																									up	30.99	n.d.		up	18.25	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		GR1307 [daf-16(mgDf50)]	20°C																																									up	29.84	n.d.		up	22.70	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		VC8 [jnk-1(gk7)]	20°C																																									up	14.17	n.d.		up	21.02	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		TK22 [mev-1(kn1)]	20°C																																									up	0.81	n.d.		up	3.42	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		AE501 [nhr-8(ok186)]	20°C																																									up	56.00	n.d.		up	49.32	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		AM1 [osr-1(rm1)]	20°C																																									up	26.80	n.d.		up	18.32	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		VC199 [sir-2.1(ok434)]	20°C																																									up	22.84	n.d.		up	17.45	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		EU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]]	20°C																																									up	50.66	n.d.		up	43.50	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		MT2605 [unc-43(n498n1186)]	20°C																																									up	53.53	n.d.		up	32.44	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		DR1567 [daf-2(m577)]	23°C																																									up	56.65	n.d.		up	26.16	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
25 µM	whole life; start: parental generation	OP50	NGM agar		AU1 [sek-1(ag1)]	15°C																																									up	0.86	n.d.		up	0.26	no		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
50 µM	whole life; start: parental generation	OP50	NGM agar		AU1 [sek-1(ag1)]	15°C																																									down	-0.28	n.d.		down	-2.14	no		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		AU1 [sek-1(ag1)]	15°C																																									down	-16.75	n.d.		down	-11.66	yes		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		DA465 [eat-2(ad465)]	20°C																																									variable	4.75	n.d.		variable	4.75	no		Saul N, Pietsch K, Menzel R, Stürzenbaum SR, Steinberg CE (2010) The longevity effect of tannic acid in Caenorhabditis elegans: Disposable Soma meets hormesis. J Gerontol A Biol Sci Med Sci 65, 626-635.	no
25 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																									none		no	A6; stressor: 35°C for 8 h; endpoint: survival	none		no	A6; stressor: 0.8 mM H2O2 for 8 h; endpoint: survival													up		yes		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
50 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																									up		no	A6; stressor: 35°C for 8 h; endpoint: survival	none		no	A6; stressor: 0.8 mM H2O2 for 8 h; endpoint: survival													up		yes		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C	down		no	A6; unchanged at A3 and A9	down		yes	A6	none		no						delayed		no		down		yes		up		yes	A6; stressor: 35°C for 8 h; endpoint: survival	up		yes	A6; stressor: 0.8 mM H2O2 for 8 h; endpoint: survival	down		yes	A1	up		yes	A1					up	17.60	yes		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
200 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																									up		yes	A6; stressor: 35°C for 8 h; endpoint: survival	up		no	A6; stressor: 0.8 mM H2O2 for 8 h; endpoint: survival													up		yes		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
300 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																									up		yes	A6; stressor: 35°C for 8 h; endpoint: survival	none		no	A6; stressor: 0.8 mM H2O2 for 8 h; endpoint: survival													none		no		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
400 µM	whole life; start: parental generation	OP50	NGM agar		N2 (wild type)	20°C																									none		no	A6; stressor: 35°C for 8 h; endpoint: survival	down		yes	A6; stressor: 0.8 mM H2O2 for 8 h; endpoint: survival													down		yes		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		TK22 [mev-1(kn1)]	20°C																																													up	3.20	yes		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no
100 µM	whole life; start: parental generation	OP50	NGM agar		DA465 [eat-2(ad465)]	20°C																																													none		no		Saul N, Pietsch K, Stürzenbaum SR, Menzel R, Steinberg CE (2011) Diversity of polyphenol action in Caenorhabditis elegans: between toxicity and longevity. J Nat Prod 74, 1713-1720.	no