Compound ID 333 (prev - next)

Name: Taxifolin (439533) (edit)

12 entries:

Treatment	Taxifolin						reproductive function				physiological function				healthspan biomarkers												lifespan								Reference
CID (PubChem)	439533	ChEMBL					number of offspring				heat stress resistance				activity / quantity / expression of SODs				activity / quantity / expression of GSTs				activity / quantity / expression of CYPs				median lifespan				maximum lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
33 µM	whole life; start: A1	OP50	NGM agar		N2 (wild type)	20°C					variable		variable	A2; Stressor: 35°C; stress exposure in S-medium; endpoint: median lifespan																					Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ (2008) Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol 43, 882-891.
164 µM	whole life; start: A1	OP50	NGM agar		N2 (wild type)	20°C					variable		variable	A2; Stressor: 35°C; stress exposure in S-medium; endpoint: median lifespan																					Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ (2008) Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol 43, 882-891.
657 µM	whole life; start: A1	OP50	NGM agar		N2 (wild type)	20°C					up	11.95	variable	A2; Stressor: 35°C; stress exposure in S-medium; endpoint: median lifespan																					Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ (2008) Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol 43, 882-891.
205 µM	whole life; start: A1	OP50	NGM agar		N2 (wild type)	20°C																					up	30.00	yes		up	11.26	n.d.	90th percentile survival	Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ (2008) Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol 43, 882-891.
150 µM	whole life; start: A1	OP50	NGM agar		N2 (wild type)	20°C	down	-7.72	no																		up	7.14	yes		up	12.02	n.d.	90th percentile survival	Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ (2008) Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol 43, 882-891.
820 µM	whole life; start: A1	OP50	NGM agar		N2 (wild type)	20°C	down	-6.75	no																		up	63.89	yes		up	9.02	n.d.	90th percentile survival	Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ (2008) Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol 43, 882-891.
820 µM	whole life; start: A1	OP50	NGM agar		CL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}	20°C													none		no	A2; measured via fluorescence													Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ (2008) Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol 43, 882-891.
820 µM	whole life; start: A1	OP50	NGM agar		CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}	20°C									up		no	A2; measured via fluorescence																	Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ (2008) Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol 43, 882-891.
820 µM	whole life; start: A1	OP50	NGM agar		unknown strain [cyp-35::GFP]	20°C																	none		no	A2; measured via fluorescence									Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ (2008) Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol 43, 882-891.