Compound ID 348   (prev - next)

Name: Urolithin C (5482042) (edit)

4 entries:
TreatmentUrolithin Cphysical functionlifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)5482042ChEMBLpharyngeal pumpinglocomotion on solid mediamean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
50 µMwhole life; start: egg stageOP50NGM agarN2 (wild type)20°CupyesA7; no significant differences at A14upnoA1, A5, A8up36yesRyu, D., Mouchiroud, L., Andreux, P. A., Katsyuba, E., Moullan, N., Nicolet-dit-Félix, A. A., ... & Aebischer, P. (2016). Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Nature medicine, 22(8), 879.