Compound ID 353 (prev - next)

Name: Vaccinum uliginosum, Alaskan bog blueberry crude extract (edit)

13 entries:

Treatment	Vaccinum uliginosum, Alaskan bog blueberry crude extract						physical function				reproductive function				healthspan biomarkers												lifespan				Transcriptome	Reference
CID (PubChem)		ChEMBL					locomotion on solid media				number of offspring				quantity of α-synuclein				ROS level				triglyceride / fat / lipid content				mean lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
100 µg/ml	whole life; start: L4	OP50-1	NGM agar	FUdR	OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}	22°C	up		yes	A12; unchanged at A5					down	-25	yes	A7									none		no			Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A., & Taylor, B. E. (2018). Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Scientific reports, 8(1), 1-13.
200 µg/ml	whole life; start: L4	OP50-1	NGM agar	FUdR	OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}	22°C	none		no	A5, A12					down		no	A7									none		no			Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A., & Taylor, B. E. (2018). Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Scientific reports, 8(1), 1-13.
400 µg/ml	whole life; start: L4	OP50-1	NGM agar	FUdR	OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}	22°C	up		yes	A12; unchanged at A5					down	-38	yes	A7; verified vie Western Blot	up		yes	A7					none		no		A7; downregulation of sir-2.1,	Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A., & Taylor, B. E. (2018). Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Scientific reports, 8(1), 1-13.
400 µg/ml	whole life; start: L3	OP50-1	NGM agar	FUdR	OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}	22°C																	down		yes	A7						Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A., & Taylor, B. E. (2018). Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Scientific reports, 8(1), 1-13.
100 µg/ml	whole life; start: L4	OP50-1	NGM agar		OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}	22°C					up		no																			Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A., & Taylor, B. E. (2018). Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Scientific reports, 8(1), 1-13.
200 µg/ml	whole life; start: L4	OP50-1	NGM agar		OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}	22°C					none		no																			Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A., & Taylor, B. E. (2018). Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Scientific reports, 8(1), 1-13.
400 µg/ml	whole life; start: L4	OP50-1	NGM agar		OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}	22°C					none		no																			Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A., & Taylor, B. E. (2018). Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Scientific reports, 8(1), 1-13.
400 µg/ml	whole life; start: L4	HT115 (DE3)	NGM agar	IPTG	OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}	22°C	up		yes	A12; unchanged at A5	none		no		down	-34	yes	A7									none		no			Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A., & Taylor, B. E. (2018). Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Scientific reports, 8(1), 1-13.
400 µg/ml	whole life; start: L4	HT115 (DE3) with RNAi-vector against sir-2.1	NGM agar	IPTG	OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}	22°C	down		yes	A12; unchanged at A5	none		no		up	29	yes	A7									none		no			Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A., & Taylor, B. E. (2018). Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Scientific reports, 8(1), 1-13.
400 µg/ml	whole life; start: L4	HT115 (DE3) with RNAi-vector against daf-16	NGM agar	IPTG	OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]}	22°C									none		no	A7														Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A., & Taylor, B. E. (2018). Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Scientific reports, 8(1), 1-13.