Compound ID 358   (prev - next)

Name: Wheat gluten hydrolysate (135305709) (edit)

6 entries:
TreatmentWheat gluten hydrolysatephysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)135305709ChEMBLlocomotion on solid mediabody length / growth ratenumber of offspringheat stress resistanceoxidative stress resistanceautofluorescence (age pigment / lipofuscin)ROS levelmean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
0.1 mg/mlwhole life; start: L4OP50NGM agarGentamycinN2 (wild type)20°CnonenoA1; endpoints: body bends and head thrashesnonenoA1nonenodownyesA12; unchanged in A1nonenoA1; measured via H2DCF-DAupyesZhang W, Lv T, Li M, Wu Q, Yang L, Liu H, Sun D, Sun L, Zhuang Z, Wang D (2013) Beneficial effects of wheat gluten hydrolysate to extend lifespan and induce stress resistance in nematode Caenorhabditis elegans. PLoS One 8, e74553.
0.5 mg/mlwhole life; start: L4OP50NGM agarGentamycinN2 (wild type)20°CnonenoA1; endpoints: body bends and head thrashesnonenoA1nonenodownyesA12; unchanged in A1nonenoA1; measured via H2DCF-DAupyesZhang W, Lv T, Li M, Wu Q, Yang L, Liu H, Sun D, Sun L, Zhuang Z, Wang D (2013) Beneficial effects of wheat gluten hydrolysate to extend lifespan and induce stress resistance in nematode Caenorhabditis elegans. PLoS One 8, e74553.
1 mg/mlwhole life; start: L4OP50NGM agarGentamycinN2 (wild type)20°CupyesA4, A8, A12, A16, and A20; unchanged in A1; endpoints: body bends and head thrashesnonenoA1nonenoupyesA2; Stressor: 35°C for 16 h; endpoint: mean lifespanupyesA2; Stressor: 2 mM paraquat for 6 h; endpoint: mean lifespandownyesA12; unchanged in A1downyesA2; pre-exposure to 2 mM paraquat for 6 h; unchanged ROS-Level without paraquat exposure in A1; measured via H2DCF-DAupyesZhang W, Lv T, Li M, Wu Q, Yang L, Liu H, Sun D, Sun L, Zhuang Z, Wang D (2013) Beneficial effects of wheat gluten hydrolysate to extend lifespan and induce stress resistance in nematode Caenorhabditis elegans. PLoS One 8, e74553.