| Treatment | α,β-Trehalose | lifespan | Transcriptome | Proteome | Metabolome | Target | Reference | blinded | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CID (PubChem) | 10871590 | ChEMBL | mean lifespan | maximum lifespan | ||||||||||||||||
| Concentration | Exposure time | Food | Growth medium | Special additives | C. elegans strain | Temperature | Change compared to control | Percentual change compared to control | p < 0.05 | notes | Change compared to control | Percentual change compared to control | p < 0.05 | notes | ||||||
| 5 mM | whole life; start: L4 | OP50, UV-inactivated | NGM agar | FUdR | N2 (wild type) | 20 °C | none | no | down | -5 | n.d. | Honda, Y., Tanaka, M., & Honda, S. (2010). Trehalose extends longevity in the nematode Caenorhabditis elegans. Aging cell, 9(4), 558-569. | ||||||||