160 µM | whole life; start: A1 | OP50 | NGM agar | | N2 (wild type) | 20°C | down | -8.93 | variable | A2; Stressor: 35°C; stress exposure in S-medium; endpoint: median lifespan; significantly decreased survival in two trials, unchanged survival (not significant) in one trial; percentual change = average of 3 trials | | | | | | | | | | | | | Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ (2008) Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol 43, 882-891. | |
4 mM | whole life; start: A1 | OP50 | NGM agar | | N2 (wild type) | 20°C | variable | | variable | A2; Stressor: 35°C; stress exposure in S-medium; endpoint: median lifespan; significantly decreased survival in one trial, increased survival (not significant) in two trials | | | | | | | | | | | | | Benedetti MG, Foster AL, Vantipalli MC, White MP, Sampayo JN, Gill MS, Olsen A, Lithgow GJ (2008) Compounds that confer thermal stress resistance and extended lifespan. Exp Gerontol 43, 882-891. | |
10 µg/ml | whole life; start: L4 | OP50 | NGM agar | | N2 (wild type) | 20°C | | | | | up | | n.d. | stressor: UV-A; medium: M9 buffer; endpoint: survival rate | down | | yes | measurement via DCF-DA and after UV-A stress | | | | | Alexpandi R, Prasanth MI, Ravi AV, Balamurugan K, Durgadevi R, Srinivasan R, De Mesquita JF, Pandian SK (2019) Protective effect of neglected plant Diplocyclos palmatus on quorum sensing mediated infection of Serratia marcescens and UV-A induced photoaging in model Caenorhabditis elegans. J Photochem Photobiol B 201, 111637. | no |