Compound ID 368   (prev - next)

Name: ß-Caryophyllene (5281515) (edit)

18 entries:
Treatmentß-Caryophyllenephysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)5281515ChEMBLpharyngeal pumpingbody length / growth ratenumber of offspringheat stress resistanceoxidative stress resistanceautofluorescence (age pigment / lipofuscin)ROS levelactivity / quantity / expression of SODsactivity / quantity / expression of SKN-1activity / quantity / expression of GSTstranslocation of DAF-16 to nucleusmean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
25 µMwhole life; start: L1OP50NGM agarFUdRN2 (wild type)20°Cup11,2yesmean from 3 individual trialsPant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarFUdRN2 (wild type)20°Cup22,2yesmean from 3 individual trialsPant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
100 µMwhole life; start: L1OP50NGM agarFUdRN2 (wild type)20°Cup14,9yesmean from 3 individual trialsPant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50, heat-inactivatedNGM agarFUdRN2 (wild type)20°Cup7,2yesmean from 2 individual trialsPant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarFUdRN2 (wild type)20°Cup12,2yesmean from 2 individual trialsPant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarFUdRTK22 [mev-1(kn1)]20°Cup13,1yesmean from 3 individual trialsPant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarFUdRDA1116 [eat-2(ad1116)]20°Cup2,5variablemean from 2 individual trials; 1 of 2 trials is significantPant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarFUdRGR1307 [daf-16(mgDf50)]20°Cup6,5yesmean from 3 individual trials; 1 of 3 trials was not significantPant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarFUdRVC199 [sir-2.1(ok434)]20°Cvariablevariableno2 individual trialsPant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarFUdREU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]]20°Cdown-1,3nomean from 3 individual trialsPant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarN2 (wild type)20°CdownyesA5 & A10downvariableA1, A2, A5, A10nonenoup16yesA2; stressor: 35°C for 7h; endpoint: survival; also significant changes by using 35°C for 4hup34yesA2; stressor: 250 µM juglone for 5 h; endpoint: survivaldown-20yesA4; blue fluorescencedownyesA4; measurement via DCF-DA in live and dead wormsA2; up-regulation of daf-16, skn-1, gst-4, gst-7, sir-2.1, sod-3, sod-2, hsp-70, daf-9, pha-4, hsf-1Pant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarTJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}20°CupnoA1Pant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarCF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}20°CupyesA1Pant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarCL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}20°CupyesA1Pant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no
50 µMwhole life; start: L1OP50NGM agarLD1 {ldIs7 [skn-1b/c::GFP + rol-6(su1006)]}20°CupyesA1Pant A, Mishra V, Saikia SK, Shukla V, Asthana J, Akhoon BA, Pandey R. (2014). Beta-caryophyllene modulates expression of stress response genes and mediates longevity in Caenorhabditis elegans. Experimental Gerontology, 57, 81-95.no