Compound ID 377   (prev - next)

Name: Chicoric acid (edit)

21 entries:
TreatmentChicoric acidphysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)ChEMBLpharyngeal pumpinglocomotion on solid mediabody length / growth ratenumber of offspringspeed of larval developmentvertex (progeny per day)oxidative stress resistanceROS leveltranslocation of SKN-1 to nucleusmedian lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperaturechange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)notes
12.5 μMwhole life; start: L4OP50NGM agarFUdRN2 (wild type)20°CnonenoPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
25 μMwhole life; start: L4OP50NGM agarFUdRN2 (wild type)20°Cup29.1yesA11; similar at A5-A9; no significant changes at A1 & A3up59yesA11; similar at A3-A9; no significant changes at A1nonenoL4/A1; worm width and worm lengthup20.8yesA1; stressor: 5 mM paraquat; endpoint: survival at A7 (similar at A3 and A5)down-14.6yesA1; measurement via DCF-DAup21.05yesPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
50 μMwhole life; start: L4OP50NGM agarFUdRN2 (wild type)20°Cup32.9yesA11; similar at A5-A9; no significant changes at A1 & A3up86yesA11; similar at A3-A9; no significant changes at A1nonenoL4/A1; worm width and worm lengthdown-19.2yesA1; measurement via DCF-DAup15.79yesPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
25 μMwhole life; start: L4OP50NGM agarN2 (wild type)20°CnonenononenononenoA1; upregulation of aak-2, nhr-49, skn-1, gsr-1, sbp-5Peng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
50 μMwhole life; start: L4OP50NGM agarN2 (wild type)20°CnonenononenononenoPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
25 μMwhole life; start: L4OP50NGM agarFUdRRB754 [aak-2(ok524)]20°CnonenoA1; stressor: 5 mM paraquat; endpoint: survival at A3, A5, A7nonenoPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
50 μMwhole life; start: L4OP50NGM agarFUdRRB754 [aak-2(ok524)]20°Cup16.67noPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
25 μMwhole life; start: L4OP50NGM agarFUdRCB1370 [daf-2(e1370)]15°Cup12.5yesPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
50 μMwhole life; start: L4OP50NGM agarFUdRCB1370 [daf-2(e1370)]15°Cup18.75yesPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
25 μMwhole life; start: L4OP50NGM agarFUdRDA1116 [eat-2(ad1116)]20°Cdown-25yesPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
50 μMwhole life; start: L4OP50NGM agarFUdRDA1116 [eat-2(ad1116)]20°Cdown-18.75yesPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
25 μMwhole life; start: L4OP50NGM agarFUdRGR1307 [daf-16(mgDf50)]20°Cup28.57yesPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
50 μMwhole life; start: L4OP50NGM agarFUdRGR1307 [daf-16(mgDf50)]20°Cup42.86yesPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
25 μMwhole life; start: L4OP50NGM agarFUdREU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]]20°Cup12.5noPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
50 μMwhole life; start: L4OP50NGM agarFUdREU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]]20°Cup12.5noPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
25 μMwhole life; start: L4OP50NGM agarFUdRTJ1052 [age-1(hx546)]20°Cup14.29yesPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
50 μMwhole life; start: L4OP50NGM agarFUdRTJ1052 [age-1(hx546)]20°Cup14.29yesPeng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no
25 μMwhole life; start: L4OP50NGM agarLD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}20°CupyesL4/A1Peng Y, Sun Q, Gao R, Park Y (2019) AAK-2 and SKN-1 Are Involved in Chicoric-Acid-Induced Lifespan Extension in Caenorhabditis elegans. J Agric Food Chem 67, 9178-9186. no