Compound ID 380 (prev - next)

Name: d-Allulose (441036) (edit)

18 entries:

Treatment	d-Allulose						physical function				healthspan biomarkers								lifespan				Transcriptome	Reference
CID (PubChem)	441036	chEMBL					pharyngeal pumping				activity / quantity / expression of SODs				activity / quantity / expression of CTLs				mean lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
5 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	N2 (wild type)	20°C					up		yes	A3	up		yes	A3	up	4	yes		A3; upregulation of sod-3, ctl-1, ctl-2	Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
10 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	N2 (wild type)	20°C	none		no	measured via food intake									up	12	yes			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
25 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	N2 (wild type)	20°C	none		no	measured via food intake									up	7	yes			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
10 mM	whole life; start: A6	none	CeMM	ampicillin, FUdR	N2 (wild type)	20°C													up	17,3	yes			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
25 mM	whole life; start: A6	none	CeMM	ampicillin, FUdR	N2 (wild type)	20°C													up	37	yes			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
10 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	DA1116 [eat-2(ad1116)]	20°C													up	2,3	no			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
25 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	DA1116 [eat-2(ad1116)]	20°C													up	1,8	no			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
10 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	GR1307 [daf-16(mgDf50)]	20°C													up	6	yes			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
25 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	GR1307 [daf-16(mgDf50)]	20°C													up	4	yes			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
10 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	VC199 [sir-2.1(ok434)]	20°C													up	7,6	yes			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
25 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	VC199 [sir-2.1(ok434)]	20°C													up	12,4	yes			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
10 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	RB754 [aak-2(ok524)]	20°C													up	0,6	no			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
25 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	RB754 [aak-2(ok524)]	20°C													down	-9,6	yes			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
10 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	unknown strain; genotype: [skn-1(tm4241)]	20°C													up	14,4	yes			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.
25 mM	whole life; start: L4	OP50-1	liquid S-medium	streptomycin, FUdR	unknown strain; genotype: [skn-1(tm4241)]	20°C													up	12,1	yes			Shintani, T., Sakoguchi, H., Yoshihara, A., Izumori, K., & Sato, M. (2017). d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic. Biochemical and biophysical research communications, 493(4), 1528-1533.