Compound ID 385   (prev - next)

Name: Enoxacin (3229) (edit)

24 entries:
TreatmentEnoxacinphysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)3229ChEMBLCHEMBL826pharyngeal pumpinglocomotion in liquid medianumber of offspringoxidative stress resistanceactivity / quantity / expression of SODsactivity / quantity / expression of GSTsactivity / quantity / expression of HSPstranslocation of DAF-16 to nucleusmedian lifespanmean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRN2 (wild type)20°CdownyesA3, A9, A12; unchanged at A6upyesA9, A12; no significant changes at A6, A15, A18upyesA1; stressor: 5 nM or 7.5 mM sodium arsenite; endpoint: survivalup19,2yesno significance in 2 out of 8 single trialsup18yesPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycinN2 (wild type)20°Cdownyesup20yesPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/ml12 h; start: A1OP50-1, heat-inactivatedNGM agarstreptomycinN2 (wild type)20°CA1; upregulation of dlg-1, magu-3Pinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdR, N-acetyl-cysteineN2 (wild type)20°CnonenoA3Pinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRDR26 [daf-16(m26)]20°CnonenoA3upyesno significance in 1 out of 5 single trialsup7yesPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdREU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]]20°CdownyesA3nonenononenoPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRCB4876 [clk-1(e2519)]20°CupyesA3upyesup28,5yesPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRRB754 [aak-2(ok524)]20°CdownyesA3upyesup26,5yesPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRTJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}20°CnonenoA3Pinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRSJ4005 {zcIs4 [hsp-4::GFP]}20°CdownnoA3Pinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRSJ4100 {zcls13 [hsp-6::GFP]}20°CdownnoA3Pinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRCL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}20°CnonenoA3Pinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRPD8753 {dcr-1(ok247); hT2 [bli-4(e937) let-?(q782) qIs48]}20°CnonenononenoPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRVC446 [alg-1(gk214)]20°CnonenononenoPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRWM49 [rde-4(ne301)]20°Cupyesup12yesPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRVC347 [mir-57(gk175)]20°CupyesPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRMT16848 [mir-249(n4983)]20°CupyesPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRVC328 [mir-47(gk167)]20°Cupyesno significance in 1 out of 5 single trialsPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRVC1051 [mir-34(gk437)]20°CupyesA9; unchanged at A3, A6, A12, and when adding N-acetyl-cysteinedownyesPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRCF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}20°CnonenoA3Pinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.
100 µg/mlwhole life; start: L4OP50-1, heat-inactivatedNGM agarstreptomycin, FUdRBB4 [adr-1(gv6); adr-2(gv42)]20°CnonenononenoPinto, S., Sato, V. N., De-Souza, E. A., Ferraz, R. C., Camara, H., Pinca, A. P. F., ... & Parmigiani, R. B. (2018). Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis. Redox biology, 18, 84-92.