Compound ID 405 (prev - next)

Name: 17ß-Oestradiol (5991) (edit)

46 entries:

Treatment	17ß-Oestradiol						cognitive function				healthspan biomarkers								Reference
CID (PubChem)	5991	ChEMBL	CHEMBL691				mechanical sensory / touch response				axonal HTT (exon-1 huntingtin)-aggregates				axonal dystrophy
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID1 {igIs1 [mec-3p::htt57-128Q::CFP; lin-15(+); mec-7p::YFP]}	20 °C					none		no		down		yes		Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}	20 °C	up		yes	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}	20 °C	up	17,4	yes	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID447 {exon1-HTT128Q::gfp; rrf-3(pk1426)}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}	20 °C	down		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}	20 °C	down		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}	20 °C	down		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	ID448 {exon1-HTT19Q::gfp; rrf-3(pk1426)}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	unnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	unnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	unnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	unnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	unnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	unnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	unnamed strain {[daf-16(mgDf50)] + [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	DR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	DR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	up		no	A1					none		no		Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	DR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	DR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	DR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	DR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	DR205 {[lon-2(e678), daf-12(m20)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	EW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	EW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	up		no	A1					none		no		Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	EW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	EW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	EW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	EW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	EW15 {[bar-1(ga80)] + ID447 [exon1-HTT128Q::gfp;rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
100 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	RB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	RB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
10 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	RB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
3.3 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	RB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	RB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.33 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	RB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}	20 °C	up		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.
0.1 µM	whole life; start: L1	OP50-1	liquid S-medium	streptomycin	RB809 {ptl-1(ok621) + ID447 [exon1-HTT128Q::gfp; rrf-3(pk1426)]}	20 °C	none		no	A1									Farina, F., Lambert, E., Commeau, L., Lejeune, F. X., Roudier, N., Fonte, C., ... & Neri, C. (2017). The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington’s disease. Scientific reports, 7(1), 1-15.