Treatment | Orlistat | healthspan biomarkers | Transcriptome | Proteome | Metabolome | Target | Reference | blinded | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CID (PubChem) | ChEMBL | triglyceride / fat / lipid content | ||||||||||||||
Concentration | Exposure time | Food | Growth medium | Special additives | C. elegans strain | Temperature | change compared to control | percentage change compared to control | significant (p < 0.05) | notes | ||||||
6 µg/ml | whole life; start: L1 | OP50 | NGM agar | N2 (wild type) | 20°C | down | yes | A1; Nile Red assay; change of -44.96% for triglycerides content | Llopis S, Rodrigo MJ, González N, Genovés S, Zacarías L, Ramón D, Martorell P (2019) β-Cryptoxanthin Reduces Body Fat and Increases Oxidative Stress Response in Caenorhabditis elegans Model. Nutrients 11, 232. | no |