Compound ID 409   (prev - next)

Name: p-Coumaric acid (637542) (edit)

17 entries:
Treatmentp-Coumaric acidphysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)637542ChEMBLCHEMBL66879pharyngeal pumpinglocomotion in liquid medianumber of offspringspeed of larval developmentheat stress resistanceoxidative stress resistanceosmotic stress resistanceROS leveltranslocation of SKN-1 to nucleustranslocation of DAF-16 to nucleusmean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
50 µMwhole life; start: L1OP50liquid S-mediumN2 (wild type)25°CdownnononenononenoA1; stressor: 37°C for 3.5 h; endpoint: survivalup17yesA1; stressor: 5 mM paraquat; endpoint: survivalup28yesA1; stressor: 500 mM NaCl; endpoint: survivaldown-34yesA1; measured vis DCF-DAA1; downregulation of osr-1Yue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
100 µMwhole life; start: L1OP50liquid S-mediumN2 (wild type)25°CdownnononenononenoA1; stressor: 37°C for 3.5 h; endpoint: survivalup17yesA1; stressor: 5 mM paraquat; endpoint: survivalup21yesA1; stressor: 500 mM NaCl; endpoint: survivaldown-25yesA1; measured vis DCF-DAA1; downregulation of osr-1Yue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
50 µMwhole life; start: L1OP50NGM agarN2 (wild type)25°CupnononenoYue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
100 µMwhole life; start: L1OP50NGM agarN2 (wild type)25°Cup5,5yesupnoYue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
50 µMwhole life; start: L1OP50liquid S-mediumFUdRN2 (wild type)25°CnonenoYue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
100 µMwhole life; start: L1OP50liquid S-mediumFUdRN2 (wild type)25°CnonenoYue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
50 µMwhole life; start: L1OP50liquid S-mediumGR1307 [daf-16(mgDf50)]25°CupyesA1; stressor: 5 mM paraquat; endpoint: survivalYue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
100 µMwhole life; start: L1OP50liquid S-mediumGR1307 [daf-16(mgDf50)]25°CupyesA1; stressor: 5 mM paraquat; endpoint: survivalYue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
50 µMwhole life; start: L1OP50liquid S-mediumEU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]]25°CnonenoA1; stressor: 5 mM paraquat; endpoint: survivalYue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
100 µMwhole life; start: L1OP50liquid S-mediumEU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]]25°CnonenoA1; stressor: 5 mM paraquat; endpoint: survivalYue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
50 µMwhole life; start: L1OP50liquid S-mediumLD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}25°Cup20yesA1Yue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
100 µMwhole life; start: L1OP50liquid S-mediumLD001 {ldIs007 [skn-1p::SKN-1::gfp]; pRF4 [rol-6(su1006gf)]}25°Cup15yesA1Yue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
50 µMwhole life; start: L1OP50liquid S-mediumTJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}25°CnonenoA1Yue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.
100 µMwhole life; start: L1OP50liquid S-mediumTJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}25°CnonenoA1Yue, Y., Shen, P., Xu, Y., & Park, Y. (2019). p‐Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Journal of the Science of Food and Agriculture, 99(3), 1190-1197.