Compound ID 62 (prev - next)

Name: Agrimonia procera, ethanol extract (edit)

33 entries:

Treatment	Agrimonia procera, ethanol extract						physical function				physiological function								healthspan biomarkers								lifespan				Target	Reference
CID (PubChem)		ChEMBL					locomotion on solid media				heat stress resistance				oxidative stress resistance				ROS level				translocation of DAF-16 to nucleus				mean lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
50 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin	N2 (wild type)	20°C													none		no	A1; measurement via DCF-DA									DAF-16	Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
100 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin	N2 (wild type)	20°C													down	-28,8	yes	A1; measurement via DCF-DA									DAF-16	Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
200 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin	N2 (wild type)	20°C													down	-55,9	yes	A1; measurement via DCF-DA									DAF-16	Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
50 μg/ml	start: L4; stop: A3	OP50	liquid NGM	BSA, tetracycline, ampicillin, FUdR	N2 (wild type)	20°C									up		yes	A3; stressor: 50 mM paraquat; endpoint: survival													DAF-16	Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
100 μg/ml	start: L4; stop: A3	OP50	liquid NGM	BSA, tetracycline, ampicillin, FUdR	N2 (wild type)	20°C									up		yes	A3; stressor: 50 mM paraquat; endpoint: survival													DAF-16	Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
200 μg/ml	start: L4; stop: A3	OP50	liquid NGM	BSA, tetracycline, ampicillin, FUdR	N2 (wild type)	20°C									up		yes	A3; stressor: 50 mM paraquat; endpoint: survival													DAF-16	Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
50 μg/ml	whole life; start: L4	OP50	liquid NGM	BSA, tetracycline, ampicillin, FUdR	N2 (wild type)	20°C					none		no	A1; stressor: 37°C; endpoint: survival																	DAF-16	Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
100 μg/ml	whole life; start: L4	OP50	liquid NGM	BSA, tetracycline, ampicillin, FUdR	N2 (wild type)	20°C					up		yes	A1; stressor: 37°C; endpoint: survival																	DAF-16	Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
200 μg/ml	whole life; start: L4	OP50	liquid NGM	BSA, tetracycline, ampicillin, FUdR	N2 (wild type)	20°C					up		yes	A1; stressor: 37°C; endpoint: survival																	DAF-16	Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
50 μg/ml	start: L4; stop: A3	OP50-1	liquid NGM	BSA, tetracycline, ampicillin, FUdR	CF1038 [daf-16(mu86)]	20°C									none		no	A3; stressor: 50 mM paraquat; endpoint: survival														Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
100 μg/ml	start: L4; stop: A3	OP50-1	liquid NGM	BSA, tetracycline, ampicillin, FUdR	CF1038 [daf-16(mu86)]	20°C									none		no	A3; stressor: 50 mM paraquat; endpoint: survival														Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
200 μg/ml	start: L4; stop: A3	OP50-1	liquid NGM	BSA, tetracycline, ampicillin, FUdR	CF1038 [daf-16(mu86)]	20°C									none		no	A3; stressor: 50 mM paraquat; endpoint: survival														Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
50 μg/ml	whole life; start: L4	OP50	liquid NGM	BSA, tetracycline, ampicillin, FUdR	CF1038 [daf-16(mu86)]	20°C					none		no	A1; stressor: 37°C; endpoint: survival																		Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
100 μg/ml	whole life; start: L4	OP50	liquid NGM	BSA, tetracycline, ampicillin, FUdR	CF1038 [daf-16(mu86)]	20°C					none		no	A1; stressor: 37°C; endpoint: survival																		Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
200 μg/ml	whole life; start: L4	OP50	liquid NGM	BSA, tetracycline, ampicillin, FUdR	CF1038 [daf-16(mu86)]	20°C					none		no	A1; stressor: 37°C; endpoint: survival																		Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
50 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin	CF1038 [daf-16(mu86)]	20°C													down		yes	A1; measurement via DCF-DA										Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
100 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin	CF1038 [daf-16(mu86)]	20°C													down		yes	A1; measurement via DCF-DA										Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
200 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin	CF1038 [daf-16(mu86)]	20°C													down		yes	A1; measurement via DCF-DA										Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
50 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin, FUdR	N2 (wild type)	25°C																					up	8,1	yes			Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
100 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin, FUdR	N2 (wild type)	25°C																					up	12,7	yes			Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
200 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin, FUdR	N2 (wild type)	25°C																					up	7,5	yes			Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
50 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin	CF1038 [daf-16(mu86)]	25°C																					none		no			Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
100 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin	CF1038 [daf-16(mu86)]	25°C																					down		yes			Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
200 μg/ml	whole life; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin	CF1038 [daf-16(mu86)]	25°C																					down		yes			Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
50 μg/ml	whole life; start: egg stage	OP50	NGM agar		CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}	16°C	none		no	A1; paralysis assay; upshift to 25°C at L3																						Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
100 μg/ml	whole life; start: egg stage	OP50	NGM agar		CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}	16°C	none		no	A1; paralysis assay; upshift to 25°C at L3																						Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
200 μg/ml	whole life; start: egg stage	OP50	NGM agar		CL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}	16°C	none		no	A1; paralysis assay; upshift to 25°C at L3																						Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
50 μg/ml	1 h; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin, FUdR	TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}	20°C																	up		no	L4						Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
100 μg/ml	1 h; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin, FUdR	TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}	20°C																	up		no	L4						Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.
200 μg/ml	1 h; start: L4	OP50-1	liquid NGM	BSA, tetracycline, ampicillin, FUdR	TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}	20°C																	up		no	L4						Saier, C., Gommlich, I., Hiemann, V., Baier, S., Koch, K., Horn, G., ... & Wätjen, W. (2018). Agrimonia procera Wallr. Extract Increases Stress Resistance and Prolongs Life Span in Caenorhabditis elegans via Transcription Factor DAF-16 (FoxO Orthologue). Antioxidants, 7(12), 192.