Compound ID 71 (prev - next)

Name: Allyl isothiocyanate (5971) (edit)

36 entries:

Treatment	Allyl isothiocyanate						reproductive function				physiological function								healthspan biomarkers								lifespan												Target	Reference
CID (PubChem)	5971	ChEMBL					number of offspring				oxidative stress resistance				oxidative stress resistance				activity / quantity / expression of UGTs				activity / quantity / expression of GSTs				median lifespan				mean lifespan				maximum lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
10 µM	whole life; start: L1	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					none	0	n.d.		down	-3.42	no		down	-5.26	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
50 µM	whole life; start: L1	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					up	9.09	n.d.		up	1.89	no		down	-10.53	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
100 µM	whole life; start: L1	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					none	0	n.d.		down	-0.34	no		none	0	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
500 µM	whole life; start: L1	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					none	0	n.d.		down	-5.36	no		up	5.26	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
1 mM	whole life; start: L1	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					down	-9.09	n.d.		down	-4.92	no		none	0	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
2 mM	whole life; start: L1	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					down	-9.09	n.d.		down	-5.21	yes		none	0	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
10 µM	whole life; start: L4	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					none	0	n.d.		down	-2.13	no		down	-10.53	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
50 µM	whole life; start: L4	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					none	0	n.d.		down	-0.50	no		none	0	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
100 µM	whole life; start: L4	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					none	0	n.d.		up	0.05	no		up	10.53	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
500 µM	whole life; start: L4	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					none	0	n.d.		down	-3.09	no		up	5.26	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
1 mM	whole life; start: L4	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					none	0	n.d.		down	-2.72	no		down	-5.26	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
2 mM	whole life; start: L4	OP50	NGM agar	FUDR	N2 (wild type)	25°C																					down	-9.09	n.d.		down	-9.51	yes		down	-10.53	n.d.			Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
10 µM	whole life; start: L4	OP50	NGM agar		MJCU049 {kIs48 [gst-4p::gfp]}	25°C																	none		no	A1; expression measured via fluorescence														Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
50 µM	whole life; start: L4	OP50	NGM agar		MJCU049 {kIs48 [gst-4p::gfp]}	25°C																	none		no	A1; expression measured via fluorescence														Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
100 µM	whole life; start: L4	OP50	NGM agar		MJCU049 {kIs48 [gst-4p::gfp]}	25°C																	up		yes	A1; expression measured via fluorescence														Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
500 µM	whole life; start: L4	OP50	NGM agar		MJCU049 {kIs48 [gst-4p::gfp]}	25°C																	up		yes	A1; expression measured via fluorescence														Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
1 mM	whole life; start: L4	OP50	NGM agar		MJCU049 {kIs48 [gst-4p::gfp]}	25°C																	up		yes	A1; expression measured via fluorescence														Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
2 mM	whole life; start: L4	OP50	NGM agar		MJCU049 {kIs48 [gst-4p::gfp]}	25°C																	up		yes	A1; expression measured via fluorescence; less induction by using HT115 (DE3) bacteria with RNAi-vector against skn-1													SKN-1	Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
10 µM	whole life; start: L1	OP50	NGM agar		N2 (wild type)	20°C	none																																	Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
50 µM	whole life; start: L1	OP50	NGM agar		N2 (wild type)	20°C	none																																	Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
100 µM	whole life; start: L1	OP50	NGM agar		N2 (wild type)	20°C	none																																	Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
500 µM	whole life; start: L1	OP50	NGM agar		N2 (wild type)	20°C	none																																	Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
1 mM	whole life; start: L1	OP50	NGM agar		N2 (wild type)	20°C	none																																	Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
2 mM	whole life; start: L1	OP50	NGM agar		N2 (wild type)	20°C	down		yes																															Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
100 µM	start: L1; stop: A3	OP50	NGM agar	FUDR	N2 (wild type)	20°C					up	6.98	yes	A3; Stressor: 10 mM paraquat; endpoint: mean lifespan	up		yes	A3; Stressor: 200 µM juglone; endpoint: mean lifespan																						Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
500 µM	start: L1; stop: A3	OP50	NGM agar	FUDR	N2 (wild type)	20°C					up	6.38	yes	A3; Stressor: 10 mM paraquat; endpoint: mean lifespan	up		yes	A3; Stressor: 200 µM juglone; endpoint: mean lifespan																						Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
1 mM	start: L1; stop: A3	OP50	NGM agar	FUDR	N2 (wild type)	20°C					up	11.6	yes	A3; Stressor: 10 mM paraquat; endpoint: mean lifespan	up		yes	A3; Stressor: 200 µM juglone; endpoint: mean lifespan																						Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
10 µM	whole life; start: L4	OP50	NGM agar		MJCU050 {kIs22 [ugt-13p::gfp]}	25°C													none		no	A1; expression measured via fluorescence																		Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
50 µM	whole life; start: L4	OP50	NGM agar		MJCU050 {kIs22 [ugt-13p::gfp]}	25°C													none		no	A1; expression measured via fluorescence																		Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
100 µM	whole life; start: L4	OP50	NGM agar		MJCU050 {kIs22 [ugt-13p::gfp]}	25°C													none		no	A1; expression measured via fluorescence																		Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
500 µM	whole life; start: L4	OP50	NGM agar		MJCU050 {kIs22 [ugt-13p::gfp]}	25°C													up		yes	A1; expression measured via fluorescence																		Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
1 mM	whole life; start: L4	OP50	NGM agar		MJCU050 {kIs22 [ugt-13p::gfp]}	25°C													up		yes	A1; expression measured via fluorescence																		Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.
2 mM	whole life; start: L4	OP50	NGM agar		MJCU050 {kIs22 [ugt-13p::gfp]}	25°C													up		yes	A1; expression measured via fluorescence; less induction by using HT115 (DE3) bacteria with RNAi-vector against skn-1																	SKN-1	Hasegawa K, Miwa S, Tsutsumiuchi K, Miwa J (2010) Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor. PLoS One 5, e9267.