Treatment | Caesalpinia sappan L. (n-butanol fraction) | lifespan | Transcriptome | Proteome | Metabolome | Target | Reference | blinded | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CID (PubChem) | ChEMBL | mean lifespan | ||||||||||||||
Concentration | Exposure time | Food | Growth medium | Special additives | C. elegans strain | Temperature | Change compared to control | Percentual change compared to control | p < 0.05 | notes | ||||||
500 µg/ml | whole life; start: egg stage | OP50 | NGM agar | N2 (wild type) | 20°C | none | no | Lee EB, Xing MM, Kim DK (2017) Lifespan-extending and stress resistance properties of brazilin from Caesalpinia sappan in Caenorhabditis elegans. Arch Pharm Res 40, 825-835. |