Compound ID 277 (prev - next)

Name: Piceatannol (667639) (edit)

23 entries:

Treatment	Piceatannol						physical function																reproductive function				physiological function								healthspan biomarkers								lifespan				Transcriptome	Target	Reference
CID (PubChem)	667639	ChEMBL					pharyngeal pumping				locomotion on solid media				body length / growth rate				body length / growth rate				number of offspring				heat stress resistance				oxidative stress resistance				ROS level				translocation of DAF-16 to nucleus				median lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
50 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	N2 (wild type)	25°C																																					up	18,33	yes				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
100 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	N2 (wild type)	25°C																																					up	18,33	yes				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
50 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	GR1307 [daf-16(mgDf50)]	25°C																																					up	3,82	no				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
100 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	GR1307 [daf-16(mgDf50)]	25°C																																					up	8,28	no				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
50 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	CB1370 [daf-2(e1370)]	15°C																																					up	4,19	no				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
100 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	CB1370 [daf-2(e1370)]	15°C																																					up	0,97	no				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
50 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	TJ1052 [age-1(hx546)]	25°C																																					down	-2,53	no				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
100 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	TJ1052 [age-1(hx546)]	25°C																																					none		no				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
50 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	VC199 [sir-2.1(ok434)]	25°C																																					up	11,3	no				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
100 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	VC199 [sir-2.1(ok434)]	25°C																																					up	14,69	no				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
50 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	MQ130 [clk-1(qm30)]	25°C																																					up	17,62	yes				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
100 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	MQ130 [clk-1(qm30)]	25°C																																					up	21,9	yes				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
50 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	DA1116 [eat-2(ad1116)]	25°C																																					up	23,04	yes				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
100 µM	whole life; start: L4	OP50	liquid S-medium	FUDR	DA1116 [eat-2(ad1116)]	25°C																																					up	20,43	yes				Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
50 µM	whole life; start: L1	OP50	NGM agar		TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}	25°C																																	up		yes	L4/A1							Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
100 µM	whole life; start: L1	OP50	NGM agar		TJ356 {zIs356 [daf-16p::daf-16a/b::GFP + rol-6(su1006)]}	25°C																																	up		yes	L4/A1							Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
50 µM	whole life; start: L1	OP50	NGM agar		N2 (wild type)	25°C	up	39.40	yes	A10; also significantly increased at A8 and A6, but not at earlier stages	up	60.00	yes	A8; also significantly increased at A10, but not at earlier stages	none		no	from L4 to young adult	none		no	L4/A1; length and width	up		no		up	300.00	yes	stressor: 35°C for 12 h; endpoint: survival	up	300.00	yes	A8; also significantly increased at A6, A4, and A2; stressor: 5 mM paraquat; endpoint: survival	down	-35.00	yes	A2; measured via H2DCF-DA									up-regulation of sod-3 and hsp-16.2	insulin/IGF-1 signaling, daf-16, and sir-2.1	Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
100 µM	whole life; start: L1	OP50	NGM agar		N2 (wild type)	25°C	up	41.90	yes	A10; also significantly increased at A8 and A6, but not at earlier stages	up	52.10	yes	A8; also significantly increased at A10, but not at earlier stages	none		no	from L4 to young adult	none		no	L4/A1; length and width	none		no		up	360.00	yes	stressor: 35°C for 12 h; endpoint: survival	up	320.00	yes	A8; also significantly increased at A6, A4, and A2; stressor: 5 mM paraquat; endpoint: survival	down	-38.00	yes	A2; measured via H2DCF-DA									up-regulation of sod-3 and hsp-16.2		Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
50 µM	whole life; start: L1	OP50	NGM agar		GR1307 [daf-16(mgDf50)]	25°C																					none		no	stressor: 35°C for 12 h; endpoint: survival	none		no	A8; also significantly increased at A6, A4, and A2; stressor: 5 mM paraquat; endpoint: survival															Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.
100 µM	whole life; start: L1	OP50	NGM agar		GR1307 [daf-16(mgDf50)]	25°C																					none		no	stressor: 35°C for 12 h; endpoint: survival	none		no	A8; also significantly increased at A6, A4, and A2; stressor: 5 mM paraquat; endpoint: survival															Shen P, Yue Y, Sun Q, Kasireddy N, Kim KH, Park Y (2017) Piceatannol extends the lifespan of Caenorhabditis elegans via DAF-16. Biofactors 43, 379-387.