| Treatment | Vaccinum uliginosum, Alaskan bog blueberry anthocyanin fraction | healthspan biomarkers | Transcriptome | Proteome | Metabolome | Target | Reference | blinded | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CID (PubChem) | ChEMBL | quantity of α-synuclein | ||||||||||||||
| Concentration | Exposure time | Food | Growth medium | Special additives | C. elegans strain | Temperature | Change compared to control | Percentual change compared to control | p < 0.05 | notes | ||||||
| 400 µg/ml | whole life; start: L4 | OP50-1 | NGM agar | FUdR | OW13 {grk-1(ok1239); pkIs2386 [unc-54p:: α-synuclein::YFP + unc-119(+)]} | 22°C | down | yes | A7 | Maulik, M., Mitra, S., Hunter, S., Hunstiger, M., Oliver, S. R., Bult-Ito, A., & Taylor, B. E. (2018). Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. Scientific reports, 8(1), 1-13. | ||||||