Compound ID 372 (prev - next)

Name: Blueberry extract (347910769) (edit)

12 entries:

Treatment	Blueberry extract						physical function								reproductive function				physiological function												healthspan biomarkers																lifespan								Transcriptome	Reference	blinded
CID (PubChem)	347910769	ChEMBL					locomotion on solid media				body length / growth rate				number of offspring				heat stress resistance				oxidative stress resistance				UV stress resistance				autofluorescence (age pigment / lipofuscin)				ROS level				activity / quantity / expression of SODs				MDA level				mean lifespan				maximum lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
50 mg/ml	whole life; start: A1	OP50	NGM agar	FUdR	N2 (wild type)	20°C	up	18	yes	A14; similar results at A18; unchanged at A9	down		no	A5					up	28	yes	A5; stressor: 35°C; endpoint: survival	up		yes	A5; stressor: 5 mM paraquat for 4h; endpoint: survival	up	74,1	yes	A5; stressor: UV-B irradiation; endpoint: survival	down	-30,4	no	A5; green fluorescence	down		yes	A5	up		yes	A5	down		yes	A5	up	22,2	yes		up	16	n.d.		upregulation of sek-1, cat-1, nhr-8; downregulation of skn-1, dod-17isp-1	Wang, H., Liu, J., Li, T., & Liu, R. H. (2018). Blueberry extract promotes longevity and stress tolerance via DAF-16 in Caenorhabditis elegans. Food & function, 9(10), 5273-5282.	no
100 mg/ml	whole life; start: A1	OP50	NGM agar	FUdR	N2 (wild type)	20°C	up	43	yes	A14; similar results at A18; unchanged at A9	down		no	A5					up	40	yes	A5; stressor: 35°C; endpoint: survival	up		yes	A5; stressor: 5 mM paraquat for 4h; endpoint: survival	up	50	yes	A5; stressor: UV-B irradiation; endpoint: survival	down	-19,4	yes	A5; green fluorescence	down		yes	A5	up		yes	A5	down		yes	A5	up	36,5	yes		up	20	n.d.		upregulation of sek-1, cat-1, nhr-8, mev-1; downregulation of dod-17, isp-1, clk-1	Wang, H., Liu, J., Li, T., & Liu, R. H. (2018). Blueberry extract promotes longevity and stress tolerance via DAF-16 in Caenorhabditis elegans. Food & function, 9(10), 5273-5282.	no
200 mg/ml	whole life; start: A1	OP50	NGM agar	FUdR	N2 (wild type)	20°C	up	48	yes	A14; similar results at A18; unchanged at A9	down		no	A5					up	56	yes	A5; stressor: 35°C; endpoint: survival	up	21	yes	A5; stressor: 5 mM paraquat for 4h; endpoint: survival	up	21,4	yes	A5; stressor: UV-B irradiation; endpoint: survival	down	-15,2	yes	A5; green fluorescence	down		yes	A5	up		yes	A5	down		yes	A5	up	44,4	yes		up	24	n.d.		upregulation of sek-1, skn-1, sod-3, cat-1, nhr-8, mev-1, sod-3; downregulation of dod-17, isp-1, clk-1, ctl-2	Wang, H., Liu, J., Li, T., & Liu, R. H. (2018). Blueberry extract promotes longevity and stress tolerance via DAF-16 in Caenorhabditis elegans. Food & function, 9(10), 5273-5282.	no
50 mg/ml	whole life; start: L4	OP50	NGM agar		N2 (wild type)	20°C									down	-6,1	yes																																							Wang, H., Liu, J., Li, T., & Liu, R. H. (2018). Blueberry extract promotes longevity and stress tolerance via DAF-16 in Caenorhabditis elegans. Food & function, 9(10), 5273-5282.	no
100 mg/ml	whole life; start: L4	OP50	NGM agar		N2 (wild type)	20°C									down	-15,4	yes																																							Wang, H., Liu, J., Li, T., & Liu, R. H. (2018). Blueberry extract promotes longevity and stress tolerance via DAF-16 in Caenorhabditis elegans. Food & function, 9(10), 5273-5282.	no
200 mg/ml	whole life; start: L4	OP50	NGM agar		N2 (wild type)	20°C									down	-24,3	yes																																							Wang, H., Liu, J., Li, T., & Liu, R. H. (2018). Blueberry extract promotes longevity and stress tolerance via DAF-16 in Caenorhabditis elegans. Food & function, 9(10), 5273-5282.	no
50 mg/ml	whole life; start: L4	HT115 (DE3) with RNAi-vector against daf-16	NGM agar	ampicillin, IPTG	N2 (wild type)	20°C																																									none		no							Wang, H., Liu, J., Li, T., & Liu, R. H. (2018). Blueberry extract promotes longevity and stress tolerance via DAF-16 in Caenorhabditis elegans. Food & function, 9(10), 5273-5282.	no
100 mg/ml	whole life; start: L4	HT115 (DE3) with RNAi-vector against daf-16	NGM agar	ampicillin, IPTG	N2 (wild type)	20°C																																									none		no							Wang, H., Liu, J., Li, T., & Liu, R. H. (2018). Blueberry extract promotes longevity and stress tolerance via DAF-16 in Caenorhabditis elegans. Food & function, 9(10), 5273-5282.	no
200 mg/ml	whole life; start: L4	HT115 (DE3) with RNAi-vector against daf-16	NGM agar	ampicillin, IPTG	N2 (wild type)	20°C																																									none		no							Wang, H., Liu, J., Li, T., & Liu, R. H. (2018). Blueberry extract promotes longevity and stress tolerance via DAF-16 in Caenorhabditis elegans. Food & function, 9(10), 5273-5282.	no