100 µM | whole life; start: A1 | HT115 (DE3) with RNAi-vector against hsp-90 | NGM agar | IPTG | N2 (wild type) | 20°C | | | | | none | | no | | none | | no | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |
100 µM | whole life; start: A1 | OP50 | NGM agar | | N2 (wild type) | 20°C | | | | | up | | yes | | up | | yes | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |
1 µM | whole life; start: L1 | OP50 | NGM agar | | TJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]} | 20°C | none | | no | A6 | | | | | | | | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |
10 µM | whole life; start: L1 | OP50 | NGM agar | | TJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]} | 20°C | none | | no | A6 | | | | | | | | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |
25 µM | whole life; start: L1 | OP50 | NGM agar | | TJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]} | 20°C | up | | yes | A6 | | | | | | | | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |
50 µM | whole life; start: L1 | OP50 | NGM agar | | TJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]} | 20°C | up | | yes | A6 | | | | | | | | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |
100 µM | whole life; start: L1 | OP50 | NGM agar | | TJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]} | 20°C | up | | yes | A6 | | | | | | | | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |
1 µM | whole life; start: A1 | OP50 | NGM agar | | TJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]} | 20°C | none | | no | A6 | | | | | | | | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |
10 µM | whole life; start: A1 | OP50 | NGM agar | | TJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]} | 20°C | none | | no | A6 | | | | | | | | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |
25 µM | whole life; start: A1 | OP50 | NGM agar | | TJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]} | 20°C | none | | no | A6 | | | | | | | | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |
50 µM | whole life; start: A1 | OP50 | NGM agar | | TJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]} | 20°C | up | | yes | A6 | | | | | | | | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |
100 µM | whole life; start: A1 | OP50 | NGM agar | | TJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]} | 20°C | up | | yes | A6 | | | | | | | | | | | | | Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. | no |