Compound ID 426   (prev - next)

Name: Tanespimycin (edit)

15 entries:
TreatmentTanespimycinhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)ChEMBLactivity / quantity / expression of HSPsmaximum lifespanmedian lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperaturechange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)notes
100 µMwhole life; start: A1HT115 (DE3) with RNAi-vector against hsp-90NGM agarIPTGN2 (wild type)20°CnonenononenoFuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no
100 µMwhole life; start: A1OP50NGM agarN2 (wild type)20°CupyesupyesFuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no
1 µMwhole life; start: L1OP50NGM agarTJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]}20°CnonenoA6Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no
10 µMwhole life; start: L1OP50NGM agarTJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]}20°CnonenoA6Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no
25 µMwhole life; start: L1OP50NGM agarTJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]}20°CupyesA6Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no
50 µMwhole life; start: L1OP50NGM agarTJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]}20°CupyesA6Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no
100 µMwhole life; start: L1OP50NGM agarTJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]}20°CupyesA6Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no
1 µMwhole life; start: A1OP50NGM agarTJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]}20°CnonenoA6Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no
10 µMwhole life; start: A1OP50NGM agarTJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]}20°CnonenoA6Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no
25 µMwhole life; start: A1OP50NGM agarTJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]}20°CnonenoA6Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no
50 µMwhole life; start: A1OP50NGM agarTJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]}20°CupyesA6Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no
100 µMwhole life; start: A1OP50NGM agarTJ3002 {zSi3002[hsp-16.2p::mCherry::unc-54;Cbr-unc-119(+)]}20°CupyesA6Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L (2019) Using the drug-protein interactome to identify anti-ageing compounds for humans. PLoS Comput Biol 15, e1006639. no