Compound ID 88   (prev - next)

Name: Ayurvedic polyherbal extract (includes 6 herbs: B. aristata roots, C.rotundus rhizome, C. deodara stem bark, E. officinalisfruits, T. chebula fruits and T. bellirica fruits) (edit)

22 entries:
TreatmentAyurvedic polyherbal extract (includes 6 herbs: B. aristata roots, C.rotundus rhizome, C. deodara stem bark, E. officinalisfruits, T. chebula fruits and T. bellirica fruits)cognitive functionphysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)ChEMBLchemotaxisaldicarb resistancepharyngeal pumpinglocomotion on solid medianumber of offspringvertex (progeny per day)heat stress resistanceoxidative stress resistanceautofluorescence (age pigment / lipofuscin)ROS leveltriglyceride / fat / lipid contentactivity / quantity / expression of SODsactivity / quantity / expression of GSTsmean lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
0.001 µg/mlwhole life; start: L4OP50NGM agarFUDRN2 (wild type)15°Cup9.67yesRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.01 µg/mlwhole life; start: L4OP50NGM agarFUDRN2 (wild type)15°Cup23.13yesRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDRN2 (wild type)15°Cup4.21yesRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.001 µg/mlwhole life; start: L4OP50NGM agarFUDRN2 (wild type)20°Cup11.09yesRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.01 µg/mlwhole life; start: L4OP50NGM agarFUDRN2 (wild type)20°CdownyesA10; blue fluorescenceup16.09yesRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDRN2 (wild type)20°Cup5.87yesRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.001 µg/mlwhole life; start: L4OP50NGM agarFUDRN2 (wild type)25°Cup23.45yesRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.01 µg/mlwhole life; start: L4OP50NGM agarFUDRN2 (wild type)25°Cup28.19yesRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDRN2 (wild type)25°Cup10.39yesRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.01 µg/mlwhole life; start: L4OP50NGM agarN2 (wild type)20°CupyesA5; attractant: 1 M sodium acetateupyesL4; stressor: 1 mM aldicarb; endpoint: ratio of non-paralyzed and paralyzed wormsdownyesA5 and A10nonenononenoup15.09yesA2; stressor: 35°C for 4 h; endpoint: survivalup50.00yesA4; stressor: 250 µM juglone for 24 h; endpoint: survivaldownyesA4; exposure to 37°C during measurement; measured via H2-DCF-DAdownyesA10up-regulation of age-1, pdk-1, daf-2, daf-16, skn-1, sod-3, and gst-4Rathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDRTK22 [mev-1(kn1)]20°Cup13.13yesRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDRDA1116 [eat-2(ad1116)]20°Cup1.77noRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDRPS3551 [hsf-1(sy441)]20°Cup2.33noRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDRGR1307 [daf-16(mgDf50)]20°Cdown-1.14noRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDREU1 [skn-1(zu67)/nT1 [unc-?(n754) let-?]]20°Cup3.63noRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDRCB1370 [daf-2(e1370)]20°Cup1.71noRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDRCL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}20°Cup34.29yesGST-4 expression; measured by fluorescenceRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDRCF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}20°Cup23.62yessod-3 expression; measured via fluorescenceRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no
0.1 µg/mlwhole life; start: L4OP50NGM agarFUDRCL4176 {smg-1(cc546); dvIs27 [myo-3p::A-Beta (1-42)::let-851 3'UTR) + rol-6(su1006)]}15°CdownyesA2; pre-exposure to 25°C; endpoint: ratio of paralyzed and non-paralyzed wormsup17.62yesRathor L, Pant A, Awasthi H, Mani D, Pandey R (2017) An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans. Biogerontology 18, 131-147. no