Compound ID 115 (prev - next)

Name: Calycophyllum spruceanum, water extract (edit)

25 entries:

Treatment	Calycophyllum spruceanum, water extract						physical function								reproductive function				physiological function				healthspan biomarkers																lifespan				Target	Reference
CID (PubChem)		chEMBL					pharyngeal pumping				body length / growth rate				vertex (progeny per day)				oxidative stress resistance				ROS level				quantity of carbonylated proteins				activity / quantity / expression of SODs				activity / quantity / expression of HSPs				mean lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
50 µg/ml	whole life; start: L1	OP50	liquid S-medium		N2 (wild type)	20°C													none		no	L4; stressor: 20 µM juglone; endpoint: mean survival	down		yes	L4; measured via DCF-DA																	DAF-16	Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
100 µg/ml	whole life; start: L1	OP50	liquid S-medium		N2 (wild type)	20°C													up		yes	L4; stressor: 20 µM juglone; endpoint: mean survival	down		yes	L4; measured via DCF-DA																	DAF-16	Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
200 µg/ml	whole life; start: L1	OP50	liquid S-medium		N2 (wild type)	20°C													up	40	yes	L4; stressor: 20 µM juglone; endpoint: mean survival	down	-80	yes	L4; measured via DCF-DA																	DAF-16	Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
300 µg/ml	whole life; start: A1	OP50	liquid S-medium		N2 (wild type)	20°C	up	58	yes	A10; similar result at A5																	down	-40	yes	A5													DAF-16	Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
50 µg/ml	whole life; start: L3/L4	OP50	liquid S-medium		N2 (wild type)	20°C					none		no	A1																														Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
100 µg/ml	whole life; start: L3/L4	OP50	liquid S-medium		N2 (wild type)	20°C					none		no	A1																														Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
200 µg/ml	whole life; start: L3/L4	OP50	liquid S-medium		N2 (wild type)	20°C					none		no	A1	down		yes																											Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
50 µg/ml	whole life; start: L1	OP50	liquid S-medium		CF1038 [daf-16(mu86)]	20°C													down		no	L4; stressor: 20 µM juglone; endpoint: mean survival																						Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
100 µg/ml	whole life; start: L1	OP50	liquid S-medium		CF1038 [daf-16(mu86)]	20°C													none		no	L4; stressor: 20 µM juglone; endpoint: mean survival																						Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
200 µg/ml	whole life; start: L1	OP50	liquid S-medium		CF1038 [daf-16(mu86)]	20°C													none		no	L4; stressor: 20 µM juglone; endpoint: mean survival																						Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
300 µg/ml	whole life; start: L1	OP50	liquid S-medium		CF1038 [daf-16(mu86)]	20°C																																	none		no			Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
50 µg/ml	whole life; start: L1	OP50	liquid S-medium		GR1307 [daf-16(mgDf50)]	20°C													none		no	L4; stressor: 20 µM juglone; endpoint: mean survival																						Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
100 µg/ml	whole life; start: L1	OP50	liquid S-medium		GR1307 [daf-16(mgDf50)]	20°C													up		no	L4; stressor: 20 µM juglone; endpoint: mean survival																						Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
200 µg/ml	whole life; start: L1	OP50	liquid S-medium		GR1307 [daf-16(mgDf50)]	20°C													up		no	L4; stressor: 20 µM juglone; endpoint: mean survival																						Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
50 µg/ml	whole life; start: L1	OP50	liquid S-medium		CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}	20°C																									up		no	L4; activity of sod-3 promotor										Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
100 µg/ml	whole life; start: L1	OP50	liquid S-medium		CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}	20°C																									none		no	L4; activity of sod-3 promotor										Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
200 µg/ml	whole life; start: L1	OP50	liquid S-medium		CF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}	20°C																									none		no	L4; activity of sod-3 promotor										Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
50 µg/ml	whole life; start: L4	OP50	liquid S-medium		TJ375 {gpIs1 [hsp-16.2p::GFP]}	20°C																													down		yes	A3; at A2: 20 µM juglone exposure for 24h; activity of hsp-16.2-promotor						Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
100 µg/ml	whole life; start: L4	OP50	liquid S-medium		TJ375 {gpIs1 [hsp-16.2p::GFP]}	20°C																													down		yes	A3; at A2: 20 µM juglone exposure for 24h; activity of hsp-16.2-promotor						Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
200 µg/ml	whole life; start: L4	OP50	liquid S-medium		TJ375 {gpIs1 [hsp-16.2p::GFP]}	20°C																													down	-63	yes	A3; at A2: 20 µM juglone exposure for 24h; activity of hsp-16.2-promotor						Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
200 µg/ml	whole life; start: A1	OP50	liquid S-medium		BA17 [fem-1(hc17)]	25°C																																	none		no			Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.
300 µg/ml	whole life; start: A1	OP50	liquid S-medium		BA17 [fem-1(hc17)]	25°C																																	up	16	yes			Peixoto, H., Roxo, M., Koolen, H., Da Silva, F., Silva, E., Braun, M. S., ... & Wink, M. (2018). Calycophyllum spruceanum (Benth.), the amazonian “tree of youth” prolongs longevity and enhances stress resistance in Caenorhabditis elegans. Molecules, 23(3), 534.