Compound ID 123   (prev - next)

Name: Catechinic acid (edit)

24 entries:
TreatmentCatechinic acidphysical functionreproductive functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)ChEMBLlocomotion on solid medianumber of offspringspeed of larval developmentquantity of early reproductionquantity of late reproductionactivity / quantity / expression of HSPsATP levelmitochondrial content/qualitymaximum lifespanmedian lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperaturechange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)noteschange compared to controlpercentage change compared to controlsignificant (p < 0.05)notes
1 µMwhole life; start: L1OP50NGM agarFUdRN2 (wild type)20°Cnonen.d.up3.4noWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
50 µMwhole life; start: L1OP50NGM agarFUdRN2 (wild type)20°Cnonen.d.up3.3noWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1OP50NGM agarFUdRN2 (wild type)20°Cupn.d.up41.9yesWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1OP50NGM agarN2 (wild type)20°CupyesA10; endpoints: speed of movement and body bends; no change at L4 and A5upyesnonenononenoupyesvariableyesdecreased at A1, increased at A8downyesA1; no significant change at A8; endpoint: ratio of mitochondrial to nuclear DNAupregulation of pink-1, sqst-1, bec-1, vps-34, lgg-1 at A1, but unchanged expression at A8; downregulation of atp-1, mev-1 at A1, but upregulation of atp-1, mev-1, sdha-1 at A8; downregulation of fzo-1 at A1;Wu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against eat-2NGM agarAmpicillin, IPTG, FUDRN2 (wild type)20°Cup22.1yesWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against daf-16NGM agarAmpicillin, IPTG, FUDRN2 (wild type)20°Cup15.4yesWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against aak-2NGM agarAmpicillin, IPTG, FUDRN2 (wild type)20°Cup6.7noWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against mev-1NGM agarAmpicillin, IPTG, FUDRN2 (wild type)20°Cup3.3noWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against bec-1NGM agarAmpicillin, IPTG, FUDRN2 (wild type)20°Cup3.1noWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against vps-34NGM agarAmpicillin, IPTG, FUDRN2 (wild type)20°Cup6.25noWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against pink-1NGM agarAmpicillin, IPTG, FUDRN2 (wild type)20°Cup3.7noWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against dct-1NGM agarAmpicillin, IPTG, FUDRN2 (wild type)20°Cup6.5noWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against sqst-1NGM agarAmpicillin, IPTG, FUDRN2 (wild type)20°Cup3noWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against skn-1NGM agarAmpicillin, IPTG, FUDRN2 (wild type)20°Cup5.5noWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1OP50NGM agarSJ4103 {zcIs14 [myo-3::GFP(mit)]}20°CdownyesA1; no significant change at A8; endpoints: mitochondrial content in gut and musclesWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1OP50NGM agarSJ4143 {zcIs17 [ges-1::GFP(mit)]}20°CdownyesA1; no significant change at A8; endpoints: mitochondrial content in gut and musclesWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1OP50NGM agarSJ4100 {zcls13 [hsp-6::GFP]}20°CdownnoA1Wu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against bec-1NGM agarAmpicillin, IPTGSJ4103 {zcIs14 [myo-3::GFP(mit)]}20°CnonenoA1;endpoints: mitochondrial content in musclesWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against pink-1NGM agarAmpicillin, IPTGSJ4103 {zcIs14 [myo-3::GFP(mit)]}20°CdownnoA1;endpoints: mitochondrial content in musclesWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against bec-1NGM agarAmpicillin, IPTGSJ4143 {zcIs17 [ges-1::GFP(mit)]}20°CupnoA1;endpoints: mitochondrial content in gutWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no
200 µMwhole life; start: L1HT115 (DE3) with RNAi-vector against pink-1NGM agarAmpicillin, IPTGSJ4143 {zcIs17 [ges-1::GFP(mit)]}20°CupnoA1;endpoints: mitochondrial content in gutWu X, Al-Amin M, Zhao C, An F, Wang Y, Huang Q, Teng H, Song H (2020) Catechinic acid, a natural polyphenol compound, extends the lifespan of Caenorhabditis elegans via mitophagy pathways. Food Funct 11, 5621-5634. no