Compound ID 175   (prev - next)

Name: Folic acid (135398658) (edit)

19 entries:
TreatmentFolic acidcognitive functionphysical functionreproductive functionphysiological functionhealthspan biomarkerslifespanTranscriptomeProteomeMetabolomeTargetReferenceblinded
CID (PubChem)135398658ChEMBLCHEMBL1622chemotaxispharyngeal pumpingbody length / growth ratenumber of offspringreproductive total spanheat stress resistanceoxidative stress resistanceautofluorescence (age pigment / lipofuscin)ROS levelactivity / quantity / expression of SODsactivity / quantity / expression of GSTsmean lifespanmaximum lifespan
ConcentrationExposure timeFoodGrowth mediumSpecial additivesC. elegans strainTemperatureChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notesChange compared to controlPercentual change compared to controlp < 0.05notes
10 µMwhole life; start: egg stageOP50NGM agarFUDRN2 (wild type)20°CdownyesA2, A5, and A10downyesA10; blue fluorescenceup17.14yesup27.44n.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
25 µMwhole life; start: egg stageOP50NGM agarFUDRN2 (wild type)20°CdownyesA2, A5, and A10upyesA5 and A10; unchanged at a2; endpoint: length and widthup26.57yesup48.40n.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
50 µMwhole life; start: egg stageOP50NGM agarFUDRN2 (wild type)20°CdownyesA2, A5, and A10up0.24nodown-9.68n.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
100 µMwhole life; start: egg stageOP50NGM agarFUDRN2 (wild type)20°Cnonen.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
250 µMwhole life; start: egg stageOP50NGM agarFUDRN2 (wild type)20°Cdownn.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
500 µMwhole life; start: egg stageOP50NGM agarFUDRN2 (wild type)20°Cdownn.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
1 mMwhole life; start: egg stageOP50NGM agarFUDRN2 (wild type)20°Cdownn.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
25 µMwhole life; start: egg stageOP50, heat-inactivatedNGM agarFUDRN2 (wild type)20°Cup14.97yesup14.16n.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
25 µMwhole life; start: egg stageOP50NGM agarN2 (wild type)20°CupyesA2; attractant: 1 M sodium acetatedown-16.95n.d.upn.d.nonenoA2; stressor: 35°C for 3 h; endpoint: survivalupyesA2; stressor: 250 µM juglone for 6 h; endpoint: survivaldown-46.80yesA2; exposed to 37°C during measurement; measured via H2DCF-DAup-regulation of pha-4, sir-2.1, daf-16, skn-1, sod-3, and gst-4Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
25 µMwhole life; start: egg stageOP50NGM agarFUDRTK22 [mev-1(kn1)]20°Cup13.29yesup16.37n.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
25 µMwhole life; start: egg stageOP50NGM agarFUDRDA1116 [eat-2(ad1116)]20°Cup0.83nononen.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
25 µMwhole life; start: egg stageOP50NGM agarFUDRGR1307 [daf-16(mgDf50)]20°Cup1.03noup11.90n.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
25 µMwhole life; start: egg stageOP50NGM agarFUDRVC199 [sir-2.1(ok434)]20°Cdown-0.32nodown-4.23n.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
25 µMwhole life; start: egg stageOP50NGM agarFUDREU31 [skn-1(zu135)/nT1 [unc-?(n754) let-?]]20°Cup3.85noup3.49n.d.Rathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
25 µMwhole life; start: egg stageOP50NGM agarCL2166 {dvIs19 [(pAF15)gst-4p::GFP::NLS]}20°CupyesA2; gst-4 expressionRathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no
25 µMwhole life; start: egg stageOP50NGM agarCF1553 {muIs84 [(pAD76)sod-3p::GFP + rol-6(su1006)]}20°CupyesA2; sod-3 expressionRathor L, Akhoon BA, Pandey S, Srivastava S, Pandey R (2015) Folic acid supplementation at lower doses increases oxidative stress resistance and longevity in Caenorhabditis elegans. Age (Dordr) 37, 113. no