Compound ID 393 (prev - next)

Name: Kinetin (3830) (edit)

10 entries:

Treatment	Kinetin						physiological function								lifespan												Reference
CID (PubChem)	3830	ChEMBL					heat stress resistance				oxidative stress resistance				median lifespan				mean lifespan				maximum lifespan
Concentration	Exposure time	Food	Growth medium	Special additives	C. elegans strain	Temperature	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes	Change compared to control	Percentual change compared to control	p < 0.05	notes
200 µM	whole life; start: L4	OP50	liquid S-medium	FUdR	N2 (wild type)	20°C	up	14	yes	A3; stressor: 35°C for 90 min; endpoint: survival; reduced effect when adding trolox	up		yes	A3; stressor: 500 µM juglone; endpoint: survival; reduced effect when adding trolox					up		yes	reduced effect when adding trolox					Kadlecová, A., Jirsa, T., Novák, O., Kammenga, J., Strnad, M., & Voller, J. (2018). Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans. Biogerontology, 19(2), 109-120.
100 µM	whole life; start: L4	OP50	liquid S-medium	FUdR	N2 (wild type)	20°C	up	5	variable	A3; stressor: 35°C for 90 min; endpoint: survival; reduced effect when adding trolox	up		yes	A3; stressor: 500 µM juglone; endpoint: survival													Kadlecová, A., Jirsa, T., Novák, O., Kammenga, J., Strnad, M., & Voller, J. (2018). Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans. Biogerontology, 19(2), 109-120.
200 µM	whole life; start: A1	OP50	liquid S-medium		BA17 [fem-1(hc17)]	25°C									up	20	n.d.	similar result in second trial	up	21	yes	similar result in second trial	up	18	n.d.	similar result in second trial	Kadlecová, A., Jirsa, T., Novák, O., Kammenga, J., Strnad, M., & Voller, J. (2018). Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans. Biogerontology, 19(2), 109-120.
100 µM	whole life; start: A1	OP50	liquid S-medium		BA17 [fem-1(hc17)]	25°C									up	5	n.d.		up	6	no		up	4	n.d.		Kadlecová, A., Jirsa, T., Novák, O., Kammenga, J., Strnad, M., & Voller, J. (2018). Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans. Biogerontology, 19(2), 109-120.
50 µM	whole life; start: A1	OP50	liquid S-medium		BA17 [fem-1(hc17)]	25°C									up	5	n.d.		up	2	no		up	2	n.d.		Kadlecová, A., Jirsa, T., Novák, O., Kammenga, J., Strnad, M., & Voller, J. (2018). Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans. Biogerontology, 19(2), 109-120.
200 µM	whole life; start: L4	OP50	liquid S-medium	FUdR	CF1038 [daf-16(mu86)]	20°C	up	15	yes	A3; stressor: 35°C for 90 min; endpoint: survival; reduced effect when adding trolox									up		yes						Kadlecová, A., Jirsa, T., Novák, O., Kammenga, J., Strnad, M., & Voller, J. (2018). Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans. Biogerontology, 19(2), 109-120.
100 µM	whole life; start: L4	OP50	liquid S-medium	FUdR	CF1038 [daf-16(mu86)]	20°C	up	10	variable	A3; stressor: 35°C for 90 min; endpoint: survival; reduced effect when adding trolox									up		yes						Kadlecová, A., Jirsa, T., Novák, O., Kammenga, J., Strnad, M., & Voller, J. (2018). Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans. Biogerontology, 19(2), 109-120.